methylenewhite
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Polio in the wild comes in three varieties, type 1, 2 and 3. Type 2 was eradicated in the wild approximately five years ago, but the vaccine caused a lingering problem—a vaccine-derived mutant virus that spreads like a wild type polio virus and can also paralyze infected people. The vaccine, called OPV2, was withdrawn from use soon after it was found that its use caused a mutant virus, but the vaccine-derived poliovirus lives on. And the only way to prevent people from being infected with it is by vaccinating them with OPV2—but reintroducing it will lead to the development of more mutant viruses. For this reason, the researchers note, a new vaccine is needed. Their work showed just how urgent that need is.
Urgently needed: New way to combat vaccine-derived poliovirus
Urgently needed: New way to combat vaccine-derived poliovirus