SERT aka serotonin reuptake transporter reduces serotonin levels. This study show that testosterone increases SERT levels whiles estradiol & anti-androgen decreases it.
High-Dose Testosterone Treatment Increases Serotonin Transporter Binding in Transgender People. - PubMed - NCBI
...SERT binding increases correlated with treatment-induced increases in testosterone levels, suggesting that testosterone increases SERT expression on the cell surface. Conversely, 4 months of antiandrogen and estrogen treatment in male-to-female transsexuals led to decreases in SERT binding in insula, anterior, and mid-cingulate cortex...
High-Dose Testosterone Treatment Increases Serotonin Transporter Binding in Transgender People. - PubMed - NCBI
...SERT binding increases correlated with treatment-induced increases in testosterone levels, suggesting that testosterone increases SERT expression on the cell surface. Conversely, 4 months of antiandrogen and estrogen treatment in male-to-female transsexuals led to decreases in SERT binding in insula, anterior, and mid-cingulate cortex...