Aldosterone Infusion Protects From Endotoxin Shock

J

j.

Guest
Influence of Aldosterone and Angiotensin II on Endotoxin Shock in the Primate

Severe endotoxin shock in monkeys resulted in hypotension, oliguria or anuria, hyperkalemia and death. No characteristic electrocardiographic findings were elicited. Aldosterone and angiotensin II were employed alone and in combination in attempts to reverse the shock. The most favorable results were obtained with a combination of the steroid and pressor drug. As in canine endotoxin shock, aldosterone markedly potentiated the pressor action of angiotensin II. Optimum results were correlated with the amount of aldosterone administered.

Link
 
OP
J

j.

Guest
Since aldosterone is often secreted when the body needs more salt, I wonder if a sodium infusion of some sort would have the same effect. I wasn't able to find such study.
 

tomisonbottom

Member
Joined
Apr 17, 2013
Messages
920
I think any of the stress hormones can be beneficial in the immediate short term for emergency situations.
 

Similar threads

Back
Top Bottom