Alcohol And Cancer: This Is How Booze Damages DNA Inside Cells

Hysteric

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Oct 18, 2017
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Came across this on the radio and had a WT* moment.

http://scienceblog.cancerresearchuk...r-this-is-how-booze-damages-dna-inside-cells/

They then gave these mice diluted ethanol, the purest form of alcohol, and used techniques to see the DNA inside the cells and read its code.

According to Patel, the results were striking and remarkable.

They found that in bone marrow samples carrying blood cells lacking the ALDH2 enzyme, just one dose of ethanol caused a build-up of acetaldehyde that seriously damaged the DNA.

“We saw huge amounts of DNA damage in these cells. Bits of DNA were deleted, bits were broken and we even saw parts of chromosomes being moved about and rearranged,” he says.

The Researcher stated that alcohol changed the DNA of the cell. I thought Ray believes otherwise. Am I wrong on my interpretation?
 
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geo78

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Joined
Sep 27, 2017
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1
Came across this on the radio and had a WT* moment.

http://scienceblog.cancerresearchuk...r-this-is-how-booze-damages-dna-inside-cells/



The Researcher stated that alcohol changed the DNA of the cell. I thought Ray believes otherwise. Am I wrong on my interpretation?
Here's your answer: "To do this, they used lab-based genetic engineering to create mice whose blood stem cells didn’t produce the enzyme ALDH2, meaning they couldn’t break down acetaldehyde."
 

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