Air pollution impairs cognition, aspirin is protective


Forum Supporter
Mar 18, 2013
USA / Europe
A new study demonstrating that even short-term (less than a month) exposure to polluted air impaired cognition in humans, and that the mechanism of action was by triggering an inflammatory response. Ergo, anti-inflammatory drugs (NSAID) and especially aspirin, were found to be protective. Since the anti-inflammatory effects of aspirin focus mostly on the COX family of enzymes, it would not be a big stretch to say that air pollution depends on PUFA to wreak havoc on the human brain. As such, dietary PUFA restriction/avoidance, is likely an even more appropriate approach to limiting the damage of pollution, especially if combined with aspirin.
Short-term exposure to air pollution may impede cognition; Aspirin could help

"...The researchers examined the relationship between exposures to fine particulate matter (PM2.5) and black carbon, a component of PM, and cognitive performance in 954 older white males from the Greater Boston Area enrolled in the Normative Aging Study. They also explored whether taking NSAIDs could modify their relationships. Cognitive performance was assessed using the Global Cognitive Function (GCF) and Mini-Mental State Examination (MMSE) scales. Air pollution levels were obtained from a site in Boston. Elevated average PM2.5 exposure over 28 days was associated with declines in GCF and MMSE scores. Men who took NSAIDs experienced fewer adverse short-term impacts of air pollution exposures on cognitive health than non-users, though there were no direct associations between recent NSAID use and cognitive performance. The researchers postulate that NSAIDs, especially aspirin, may moderate neuroinflammation or changes in blood flow to the brain triggered by inhaling pollution."


Jul 10, 2016
I have the unfortunate luck of facing a main street and despite about 10 metres of garden and trees/shrubs between it and my windows it's inevitable for the pollution to get it especially in early spring and fall.

It's estrogenicity is blatant and I try to counter it by keeping all windows closed during "rush hours" to at least reduce it a bit though inevitable. I do take 1 gram of Aspirin per week.

Funny thing to the back of my building I have a HUGE park adjacent to a river trail, quite hilly and covered in large swaps of woods where the air is beautiful close to Lake Ontario.... Wished I lived facing that side.

Actually wished I lived in the country so I could see stars at night! Hahah.


EMF Mitigation - Flush Niacin - Big 5 Minerals

Similar threads

Top Bottom