Aging Fast & Alien Confusion

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“A chronic increase of lactic acid and cortisol indicates that something is wrong. The “slender muscles” of endurance runners are signs of a catabolic state, that has been demonstrated even in the heart muscle. A slow heart beat very strongly suggests hypothyroidism. Hypothyroid people, who are likely to produce lactic acid even at rest, are especially susceptible to the harmful effects of “aerobic” exercise. The good effect some people feel from exercise is probably the result of raising the body temperature; a warm bath will do the same for people with low body temperature.” -Ray Peat
 
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“Exercise increases blood clotting, and so can increase the risk of strokes and heart attacks. Some doctors have been reporting increase incidence of flat feet, varicose veins, and prolapsed uterus among runners. Walking is a better form of exercise.” -Ray Peat
 
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“As the study below shows, fasting or exercising and then stopping (in the face of unchanged caloric intake), leads to rapid regaining of weight, insulin resistance and obesity. The effects are due to cortisol, which stays elevated after stopping the fasting/exercise due to elevation in 11b-HSD1 expression. I think this is what quite a few people experienced on Peat's diet. Due to their lowered metabolic rate and reliance on cortisol and adrenaline from diets like Paleo and/or chronic exhaustive exercise, these people rapidly regain weight initially post exercise/fasting and struggle with losing it unless they lower their stress hormones and support thyroid. Unless thyroid is addressed and/or excessive cortisol signalling opposed the fasting/exercise needs to be done indefinitely in order to keep the weight off. This would explain why some people here need to endure long fasts to feel good - once you are in the vicious circle of IR and obesity you either have to keep feeding that cycle or block/lower cortisol to exit it.”
 
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“Elite athletes are generally considered to have “good genes,” and exercise is commonly said to promote good health, so a new orientation is needed to accommodate the fact that “elite” athletes, winter or summer athletes, including participants in the Olympics, have a high incidence of asthma — roughly three times higher than the general population.

It turns out that exercise induces the signs and symptoms of asthma, not only in “asthmatics,” but in normal people too.

Anaerobic exercise (getting out of breath) increases the release of, or activity of, a large variety of inflammatory mediators, beginning with lactic acid and interleukin-6 releases from the exercised muscle itself, and including factors released from various cells in the blood, and hormones including estrogen, prolactin, and sometimes TSH.
-Ray Peat

 
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“Many dietitians claim that exercise doesn’t increase the need for protein, but the Russians have found that a combination of exercise and increased protein intake can increase the muscle mass. In a woman, this process can not only improve grace and body proportions, but it also increases the body’s ability to burn up fat. Other nutrients are needed for using protein properly, and for maintaining optimum nerve functioning. However, if the exercise produces too much stress and not enough muscle action, muscle will atrophy as a result of cortisone’s shifting amino acid metabolism into glucose production. Lactic acid production (getting out of breath) is the main signal of the need to produce new glucose. Therefore, “aerobic” exercise is the most stressful. Cortisone not only causes atrophy of the skin, muscles, and immune system, but it even has been found the accelerate aging changes in the brain.” -Ray Peat
 
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“Exercise increases blood clotting, and so can increase the risk of strokes and heart attacks. Some doctors have been reporting increase incidence of flat feet, varicose veins, and prolapsed uterus among runners. Walking is a better form of exercise.” -Ray Peat
 
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“Can Vaping Affect Muscle Gain?​

weight lifting

Believe it or not, vaping actually does slow muscle growth. Well, at least using nicotine does. Apoptosis is the process that our bodies use to make new cells and grow muscle. Nicotine impacts this, causing it to slow[2].

If you’re trying to gain muscles, consider switching to a lower strength or using nicotine free liquids.”

 

proteome

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Your ancestors spent the day doing physical labor. You sit on a chair working on excel sheets. Gym is just means of compensating for this newfound sedentariness, lest you need to become physically crippled and ridden with painful postural imbalances by the time you turn 50. Lack of strength and fitness is not something to rave about.
Yes, some of our unnatural "health" culture is a cope for deeper health issues.

Vitamin D3 and "exercise" or "fitness centers" all seem to compensate, rightly enough, for not spending enough time outside doing sweaty things.
 
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This was posted by @haidut elsewhere…

“By exercising, you are forcefully burning calories through stress (cortisol/adrenaline) and that has been shown to be highly detrimental. The only exercise that is beneficial is glycogen-bound - e.g. weight lifting done in a way that builds muscle and keeps lactate at bay, walking at a pace that allows you to hold a conversation without breathing through your mouth, maybe even running (subject to the same restrictions). Exercise may work when you are in your 20s and can produce enough DHEA to counter the cortisol/adrenaline from the exertion. Once your gonadal steroids and pregnenolone/DHEA start to decline (30+ yo) then exercise (at least the officially recommended forms of it) becomes nothing but serious stress that is entirely detrimental and it pushes you further into the hole of insulin resistance and obesity.”

 
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Haidut said…

“But assuming every marathon run can cause even temporary kidney failure for 80%+ of runners then it is something a person should probably not be doing, either short- or long-term.
I would definitely like to see this replicated with a much bigger group, which should be easy to do given how many large scale, general population marathons occur in the US every year.”

 
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“Hopefully, this post won't be interpreted as trying to bash exercise. Its goal is to simply draw attention to the fact that intense exercise can be detrimental even for elite athletes. While the damage the study observed was temporary, it is now known that (just like ionizing radiation) the damage of chronic stress / overtraining may be cumulative, which means it should be avoided as much as possible. Speaking of elite athletes - they are known to have much higher rates of CVD, cancer, and neurodegenerative disease after the completion of their careers, and some of them experience those issues while still actively competing and in top shape. So, the moral of the story to me is this - do not overtrain and/or avoid chronic stress (even if it appears mild)! Looking slim and fit is not always a sign of good health.”

 

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