"Age-pigment is an oxidized mass of unsaturated fat & iron."


Jul 22, 2012
"...Excess iron's role in infectious diseases is now well established, and many recent studies show that it is involved in degenerative brain diseases, such as Parkinson's, ALS (Lou Gehrig's disease), Huntington's chorea, and Alzheimer's disease. Iron is now believed to have a role in skin aging, atherosclerosis, and cataracts of the lenses of the eyes, largely through its formation of the 'age pigment.'

"During aging, our tissues tend to store an excess of iron. There is a remarkably close association between the amount of iron stored in our tissues and the risk of death from cancer, heart disease, or from all causes. This relationship between iron and death rate exists even during childhood, but the curve is downward until the age of 12, and then it rises steadily until death. The shape of this curve, representing the iron burden, is amazingly similar to the curves representing the rate of death in general, and the rate of death from cancer. There is no other relationship in biology that I know of that has this peculiar shape, with its minimum at the age of 12, and its maximum in old age at the time of death.

"One of the major lines of aging research, going back to the early part of this century, was based on the accumulation of a brown material in the tissues known as 'age-pigment.' The technical name for this material, 'lipofuscin,' means "fatty brown stuff." In the 1960s, the 'free radical theory' of aging was introduced by Denham Harman, and this theory has converged with the age-pigment theory, since we now know that the age-pigment is an oxidized mass of unsaturated fat and iron, formed by uncontrolled free radicals."

Dr. Ray Peat
from "Iron's Dangers."


Thread starter
Jul 22, 2012
Re: "Age-pigment is an oxidized mass of unsaturated fat & ir

"...The accumulation of iron and other heavy metals, and of unsaturated fats, and the progressive loss of copper under the influence of the stress of darkness, are probably the central events in the process of aging.”
--Dr. Ray Peat
quoted on Danny Roddy's Website

I haven't found the primary source.
Similar threads
Thread starter Title Forum Replies Date
Richiebogie The Age Pigment Lipofuscin And The Fountain Of Youth Ray Peat Quotes 25
J Age Pigment: Cause And Effect Of Aging And Stress Articles & Newsletters 15
GorillaHead Total exchangeable potassium decreases as we age! Diet 3
Sefton10 Stone Age humans were Hypercarnivores Diet, Recipes 8
M Macular Degeneration in young age - pls help Ask For Help or Advice 47
Mauritio Drug Reverses Age-Related Mental Decline Within Days Articles & Scientific Studies 11
F Small Molecule Cognitive Enhancer Reverses Age-Related Memory Decline In Mice Scientific Studies 1
Quelsatron Sweden May Make Preschool Obligatory From The Age Of Two Breaking News 0
TheSir At What Age Do Men Get 'baby Fever'? Ask For Help or Advice 11
L Younging1 - Age Reversal Is Real Miscellaneous Health Discussions 15
B Marxism And The New Age Progressive Movements Political Talk, Alternative World Theories 179
meatbag Declining Age Of Puberty Onset Across The Globe Children 2
GorillaHead What Is The Cause Of Dual Bulging Temple Veins At An Early Age ? Skin 3
J Is It Possible To Grow Bone Structure At The Age Of 21? Ask For Help or Advice 14
Mito Severe Infections Of COVID-19 In Millennial Age Group Articles & Scientific Studies 5
Jamesu Self Help In The Age Of Neo-liberalism Health 68
yerrag Why Do We Accept Age As The Defining Factor For Metabolic Rate? Metabolism 3
G Human Age Reversed By 2.5 Years By Combo Of Metformin, DHEA And GH Scientific Studies 54
P Does Marijuana Smoking Age Skin? Skin 14
haidut Niacinamide May Restore Female Fertility In Old Age Scientific Studies 17
haidut While Estradiol Falls, Estrone Rises With Age And Is Much More Relevant For Estrogen-driven Diseases Scientific Studies 6
ecstatichamster The Cure To Old Age - Dr. Peat September 1995 Science 122
M How Toilet No2's Change As We Age Health 6
haidut The Coming Ice Age Scientific Studies 11
haidut Deficiency Of Vitamin K Involved In Age-related Disability / Frailty Scientific Studies 1
M Supplements By Age? Supplements, Pharmaceutical Drugs 3
haidut Fertility Depends On Metabollism (ATP), Not Age Scientific Studies 17
jzeno Luke Perry, Of '90210' Fame, Dead At Age 52--Died Of Result Of Massive Stroke Breaking News 2
GAF New-drug-hopes-reversing-memory-loss-old-age-depression-schizophrenia-alzheimers Alzheimer's 3
Captain_Coconut True Or False? Pregnenolone Does Not Decrease With Age Hormones 3
X Taking DHEA At The Age Of 17. Is It Normal? DHEA 3
L Can Young Men (age Between 18-30) Benefit From Taking Pregnenolone, If Their Metabolism Is Good? Pregnenolone 44
L Preg, Prog, DHEA Skincare/anti-age Body Care 8
Hugh Johnson Turpentine To De-age The Body Health 1
ecstatichamster Dr. Peat Is Right About Blood Pressure Higher = Better As People Age Heart, Heart Rate, Blood Pressure 10
9 Ray Peat Has Grey Hair, No Facial Hair, Black Teeth And Age Pigments Rant or Rave 102
x-ray peat Age Related Macular Degeneration Scientific Studies 5
A Age And Testosterone Levels Hormones 0
haidut Naked Mole Rats Do Not Age Scientific Studies 56
Mito High-intensity Interval Training Improved Age-related Decline In Muscle Mitochondria Exercise 4
7 Controversial Question: How To Age Myself Faster? Ask For Help or Advice 53
K Testosterone Declines With Age, Your Opinion Hormones 8
B New Jersey Raises Minimum Smoking Age To 21 Political Talk, Alternative World Theories 2
haidut Grey Hair May Be A Biomarker For CVD (and Biological Age) In Men Scientific Studies 25
L Daily-dose-of-cannabis-extract-could-reverse-brains-decline-in-old-age Scientific Studies 4
D Thoughts On Being Unhealthy At A Young Age Rant or Rave 12
Dan Wich T4 Treatment In "subclinical" Hypothyroid In People Age 65+ Scientific Studies 2
D If Liver De-Toxifies, What Did It Do Before The Industrial Age Toxins, Detoxification 15
Mito "Biggest Loser" Fitness Guru (age 51) Suffers Serious Heart Attack The Ray Peat Forum Lounge 144
Mito Caffeine May Counter Age-related Inflammation Scientific Studies 2

Similar threads