johnwester130
Member
- Joined
- Aug 6, 2015
- Messages
- 3,563
if DHT damages the prostate
How do the medical industry and scientists explain this ?
How do the medical industry and scientists explain this ?
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Genetic sensitivity for balding - so they say. A dude who once appeared for a while on this forum said even young people who died due to other causes after biopsies were found to have prostate cancer(search the forum , you might find his post, he had some valid points though)if DHT damages the prostate
How do the medical industry and scientists explain this ?
Genetic sensitivity for balding - so they say. A dude who once appeared for a while on this forum said even young people who died due to other causes after biopsies were found to have prostate cancer(search the forum , you might find his post, he had some valid points though)
You want another realization? Approach any psychiatrist and say that lithium can treat ALL psychiatric disorders and its only accepted mechanism of action is metabolic (restores brain mitochondrial function). So, are all mood disorders metabolic disorders?
Do you think it's possible lithium would correct a slow brain and/or stutters? Or am I reaching too much with the statement above?Every male over the age of 30 likely has some form of prostate cancer. It is estrogen-driven not androgen-. Just because something makes your prostate grow does not make it cancerous. Cancer is always preceded by atrophy in the tissue, which in the prostate is done by estrogen, not androgens. Androgens make the prostate, gonads, and seminal vesicles grow - i.e. it is a healthy, well-differentiated hypertrophy. I have never seen such a twisted version of reality being sold - i.e. we have to castrate men to save them from disease.
As far as the realization you reached - I have brought this up to every urologist I know. The reaction I get, if they are friendly enough to not dismiss me outright, is either angry huff or exasperation/confusion like in the picture below.
View attachment 4735
You want another realization? Approach any psychiatrist and say that lithium can treat ALL psychiatric disorders and its only accepted mechanism of action is metabolic (restores brain mitochondrial function). So, are all mood disorders metabolic disorders? I had one doctor acquaintance reach for his Prozac while choking on his salad and another one who said I should not be volunteering this information publicly is I want to ever be employable by any company. Two others had not even heard of lithium used for anything beyond bipolar disorder and the fifth one said "what is lithium?".
Really? ALL disorders? That's impressive.
I have found that a glass of orange juice or soda will quickly elevate my mood after a long or tough day. Seriously, within 15 minutes. Would Lithium also be useful when under stress, or during a demanding mental project?
"The mechanism for this is not fully understood but current theories include alterations of the AR gene, coregulator proteins and/or signal transduction pathways."
Great example of the vanity of scientists...we aren't just flat wrong, we are right even in our wrongness.
Too be honest I'm not even sure this has much to do with androgens.
It depends on what causes "anti-androgen withdrawal syndrome".
If anti-androgen withdrawal syndrome (AAWS) is caused only by AR antagonists, then I don't think it has much to do with androgens.
If AAWS is caused not only by AR antagonists, but also by chemicals that inhibit androgen synthesis, then I think androgens play an important part.
But the wiki page that talks about AAWS only mentions AR antagonists, not androgen synthesis inhibitors.
Let's take a look at some of the anti-androgens that wiki mentions.
To me, the "paradoxical" reaction to AR antagonists has more to do with the fact that the main AR antagonists used are halogenated flourine clusterfucks.
That can't be good for the parts of the body which exhibit AR and are thus exposed to high levels of these chemicals.
Funnily enough, AR antagonists also raise testosterone and estrogen, because of the feedback loop (the body senses low androgenic tone and thus increases productions of androgens)
Maybe that has something to do with it as well.
Androgen synthesis inhibitors not only lower testosterone, but estrogen as well.
AR antagonists raise both.
I'll say it like this: I think a large part of the withdrawal has to do with the chemicals that block AR. The lack of androgen signaling probably has a part to play as well.
I am always on the look-out for red-herrings and misdirection.
I hope this makes sense.
@haidut "restores brain mitochondrial function"
Does it have any permanent effects? What type or which product is good?
Actually, it is precisely the negative effects of AR antagonists that implicate androgens as being protective. The androgen synthesis inhibitors in use clinically are mostly 5-AR inhibitors like finasteride and dutasteride so they mostly reduce availability of DHT. But something like flutamide (AR antagonist) will block the effects of all androgens, including weak ones like DHEA, androstenedione, and androstenediol as well as less commonly considred ones like androstanediol and androstanedione.
I'm saying that the substances used to antagonise AR could also have a part to play in AAWS.
By androgen synthesis inhibitors I meant things like synthetic progestins or anti-gonadotropins, that block sex hormone production at the source.
Well this explains. Certainly not a carrot salad.I had one doctor acquaintance reach for his Prozac while choking on his salad
It takes many years to develop a noticeable form of cancer, and prostate cancer has a relatively high survival rate. It's just not a very good argument.
Well this explains. Certainly not a carrot salad.
As user @Such_Saturation posted long time ago, and maybe can find the study again, lithium kills the brain cells with mitochondria damages beyond repair. It also chelates ammonia and improves function of ETC complxes I, II, and IV. Nothing is permanent, but it definitely reverses the pathology as old lithium protocols did not last a lifetime. The longest one was 3 months I think and most were a few weeks long and then the treatment stopped.