1998 NYT Article CALCIUM/CANCER

beta pandemic

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this was the most interesting part for me:

Effect on Cancers

"Tissues throughout the body are lined with epithelial cells like the ones that form the outer layer of skin. They grow, mature, slough off and are replaced by new ones. In the lining of the colon, where cancers arise, the turnover of epithelial cells normally takes a week. But in people prone to colon cancer, these cells fail to grow and mature normally and instead immature cells proliferate rapidly."

Let this sink in:

In the lining of the colon, where cancers arise
In the lining of the colon, where cancers arise
In the lining of the colon, where cancers arise
In the lining of the colon, where cancers arise
In the lining of the colon, where cancers arise
In the lining of the colon, where cancers arise
In the lining of the colon, where cancers arise


I'v had this hunch for a while that cancer is an abnormal overgrowth of an pathological organism which begins in the colon. An infection if you like. This organism grows and grows to a point where its toxic ( and acidic) metabolites (endotoxin??) overwhealm the body (alkaline mineral reserves mainly calcium potassium magnesium and various stress hormones) and it disrupts normal energy metabolism. Dr Otto Warburg has touched on this subtly cant remember the exact quote but he talks about cancer as a machine growing uncontrollably inside the body, like an organism within an organism (parasite) transforming the hosts metabolism permanently (fermentation).

the rest of the article:

"Dr. Martin Lipkin of the Strang Cancer Research Laboratory at Rockefeller University in New York described studies showing that calcium could bind tightly to these irritants and inhibit their ability to stimulate cell proliferation. With calcium present, as it would be on a calcium-rich diet, the cells differentiate and mature like normal epithelial cells."

"Dr. Lipkin and his colleagues showed that calcium supplements could inhibit colonic cell proliferation in people susceptible to colon cancer."

"When participants' consumption of low-fat, calcium-rich dairy products was doubled, reaching 1,200 milligrams of calcium a day, cell growth in the colon became normal."

"As the most abundant mineral in the body, calcium has long been recognized as vital to the formation and maintenance of strong bones and teeth. But bones, rather than serving as the final destination of calcium, are in a sense, just a starting point. They continuously release the mineral into the system where new research suggests it may play a central role in controlling blood pressure and easing premenstrual syndrome, or PMS. In addition, new studies indicate that unused dietary calcium may help to prevent colon cancer."

"if the body does not receive enough dietary calcium to maintain the needed blood level, parathyroid hormone leaps to the rescue. Its job is to signal the release of calcium from the bones to restore a normal blood level of this life-sustaining mineral. If the diet is chronically deficient in calcium (or vitamin D), as it is for as many as three-fourths of Americans, the bones gradually get weaker and weaker."

"The new research has come in a flurry. Just in the last two months, a New York research group reported that eating more calcium-rich foods reduced the risk of colon cancer in men prone to the disease, and another New York-based team described a 50 percent reduction in life-disrupting premenstrual symptoms among hundreds of women who took daily calcium supplements."

"calcium is required for myriad body functions:

*Transmission of nerve impulses that control muscle contractions.

*Release of chemicals that carry messages between nerves.

*Binding together of cells to form organs.

*Production and activity of enzymes and hormones that regulate digestion, fat metabolism, energy release and saliva production.

*Clotting of the blood to initiate wound healing.

*Secretion of hormones and other substances from glands throughout the body.

*Chemical signaling within cells.

*Growth and maturation of lining cells throughout the body.

''It's not surprising that calcium plays so many roles,'' said Dr. Hector F. DeLuca, a biochemist at the University of Wisconsin who is an expert on vitamin D and calcium metabolism. ''Since all life originated in the sea in a bath containing calcium, we all developed systems that depend on it.''

"women with PMS might have a form of ''functional hypocalcemia'' -- calcium levels in their blood and urine are normal, but only because parathyroid hormone levels are abnormally high and the hormone is continually extracting calcium from their bones to replenish the blood's supply."

"Calcium is a lot more than simply bone health,'' Dr. McCarron concluded. ''It may even influence behavior,'' he said, citing a space shuttle study in which rats bred to become hypertensive were ''frantic'' on a low-calcium diet, but when fed more calcium, ''they relaxed and enjoyed the space flight."

http://www.nytimes.com/1998/10/13/h...s-place-as-a-superstar-of-nutrients.html?_r=0
 

charlie

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burtlancast

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terminator.jpg

But but...



According to Dr Levy, that is...
 

PeatThemAll

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The big question: other than the RDA, and where you stand in its bell curve distribution, how do you know (by feel) if you're taking in too much or not enough???
 

Luann

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The big question: other than the RDA, and where you stand in its bell curve distribution, how do you know (by feel) if you're taking in too much or not enough???

Anyone else remember Wild Fermentation and their WAPF days, and being told that if one of your bacteria foods is going bad, "you'll know"? "The nose knows"? That's kinda how calcium seems to be. Calcium deficiency just feels, strained. Unhappy.
 

Giraffe

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According to Dr Levy, that is...
This Dr Levy talks about the magnesium, vitamin D and vitamin K in the prevention of osteoporosis and other degenerative diseases, but no mention of the parathyroid hormone, and that's where he gets plain wrong.

[paraphrased] Calcium supplementation alone does not decrease fracture incidence. It's vitamin D supplementation that does the trick.

When I looked for a human study that did only supplement calcium, the first one that popped up was a randomized placebo-controlled study that showed a marked reduction in risk. Unadjusted hazard ratio: 0.28, after adjustment 0.21.

Effect of calcium supplementation on fracture risk: a double-blind randomized controlled trial, ,

I think it is worth mentioning that they supplemented with calcium carbonate (3 g = 1,200 mg elemental calcium) and not with the widely used calcium citrate. Peat is not a fan of calcium citrate. See post.
........

Dr Levy quoted a Swedish study saying that high dietary calcium intake combined with supplemental calcium increased all-cause mortality by factor 2.5. (What he said contradicted his own slides, and it contradicts the study somewhat.) (full text link)

According to table 2 the age adjusted hazard ratio was highest in the group with the lowest total calcium intake (< 600 mg/day including supplements) and lowest in the group with the highest total calcium intake (>1.400 mg/day): 1.59 vs. 0.72. After adjustment for all sorts of factors the hazard ratio in both groups was 1.4.

It gets confusing when they try to sort by people who supplemented calcium and those who didn't (table 3). The results are all over the place.

There are a few points where I disagree with the study (part of the conclusion, the design ...). However they concluded that "Mortality was not increased between 600 and 1400 mg/day of total calcium intake, the most customary levels of intake in this setting."

Now think that the RDA for most adults in the US is 1,000 mg per day, and the majority of the population doesn't meet it. So this Dr Levy is claiming that dairy is toxic because it contains calcium? And this study is all he as to offer to support his claims?

Magnesium and calcium dietary intakes of the U.S. population. - PubMed - NCBI
 
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