100% Oxygen Therapy To Reverse Aging?

[RWilly]

Just came across this, which surprised me.

"Shai Efrati claims he has found that when healthy adults aged 65-plus were given a special oxygen therapy, their cognitive function improved and so did the brain’s tissue function."

[...]

"Efrati recruited 63 people aged 65-plus, took MRI scans and tested their cognitive abilities. He then gave some of them a 60-day course of treatment during which they spent 2-hour stints in a pressurized chamber five times a week, breathing pure oxygen for some of the time.

At the end of the experiment, those who didn’t go in the hyperbaric chamber had similar MRI results as they did at the start, and similar cognitive ability. But Efrati reported a significant difference on those who received the oxygen therapy — and found the improvements held in tests six months later.

“In these people, MRI scans showed that tissue function in the brain, in areas associated with cognitive decline, had improved, and we also found a significant improvement in cognitive function,” he said, stressing that staff carrying out the assessments didn’t know which patients had received the therapy."

Israeli doctor claims to ‘reverse’ aging with pure oxygen treatment study

 

[boris]

Seems to be an effect of the pressure and the intermittent exposure creating an effect similar to a higher CO2 to O2 ratio?

https://paperchase-aging.s3-us-west-1.amazonaws.com/pdf/28Xj8TqwuxopAdkAj.pdf
"Hyperbaric oxygen therapy (HBOT) utilizes 100% oxygen in an environmental pressure higher than one absolute atmospheres (ATA) to enhance the amount of oxygen dissolved in body’s tissues. Repeated intermittent hyperoxic exposures, has been shown to induce physiological effects which normally occur during hypoxia in a hyperoxic environment, including stem cells proliferation and generation of new blood vessels (angiogenesis)"

"Our protocol included 60 sessions of 100% oxygen at 2 ATA including 3 air breaks during each session in order to utilize the hyperoxic hypoxic paradox and minimize the risk for oxygen toxicity."

 

[RWilly]

Seems to be an effect of the pressure and the intermittent exposure creating an effect similar to a higher CO2 to O2 ratio?

https://paperchase-aging.s3-us-west-1.amazonaws.com/pdf/28Xj8TqwuxopAdkAj.pdf
"Hyperbaric oxygen therapy (HBOT) utilizes 100% oxygen in an environmental pressure higher than one absolute atmospheres (ATA) to enhance the amount of oxygen dissolved in body’s tissues. Repeated intermittent hyperoxic exposures, has been shown to induce physiological effects which normally occur during hypoxia in a hyperoxic environment, including stem cells proliferation and generation of new blood vessels (angiogenesis)"

"Our protocol included 60 sessions of 100% oxygen at 2 ATA including 3 air breaks during each session in order to utilize the hyperoxic hypoxic paradox and minimize the risk for oxygen toxicity."

Interesting thought. Hadn't considered a pressure component. But how would that theory work in high altitude?