vitamin b6

  1. Bluebell

    Dosages Of Thiamine, Riboflavin, Niacinamide, Pyridoxine, And Biotin

    I was wondering what might be good dosages of thiamine, riboflavin, niacinamide, pyridoxine, and biotin. I currently take the following and was wondering if the doses are OK: (I recently stopped for a few days then restarted as I find I feel better when I take them) thiamine 100mg riboflavin...
  2. haidut

    Vitamin B6 (P5P) Functions As A PPI

    If I am reading this right, P5P acts like a PPI. This would explain some of the protective effects of P5P on stress-induced gastric ulcers in animals and men. http://www.jbc.org/content/263/8/3652.long "...Pig gastric membrane vesicles enriched in (H++K+)-ATPase were covalently modified with...
  3. haidut

    Vitamin B6 (P5P) Is An ACC Inhibitor And May Treat Obesity

    It seems vitamin B6 is especially important for the metabolism of long-chain fatty acids, which include the dreaded EPA, DHA, and arachidonic acids. The dosages of P5P that inhibited ACC-1 and ACC-2 in vitro are close to physiological and what is achievable by supplementation. Typical...
  4. haidut

    Vitamin B6 (P5P) Is A Glucocorticoid (cortisol) Antagonist

    The studies go back to 1960s and 1970s but when I read them I was surprised to find that the activated form of vitamin B6 called pyridoxal-5-phosphate (what we also use for our Energin supplement) is a glucocorticoid "receptor" antagonist. Some of the in vivo studies referenced in the studies...
    • haidut
    • Thread
    • antagonist cortisol glucocorticoid p5p study vitamin b6
    • Replies: 10
    • Forum: Scientific Studies
  5. haidut

    Vitamin B6 deficiency promotes PUFA accumulation in tissues

    So, make sure you ingest enough vitamin B6 while working to deplete PUFA stores. http://www.ncbi.nlm.nih.gov/pubmed/6481472 "...In -PN rats, phospholipid levels of linoleic and gamma-linolenic acids were increased, but arachidonic acid was decreased compared to controls in plasma, liver...
  6. haidut

    Using Vitamins (pyridoxine) For Improving Glucose Control

    This post is on vitamin B6 (pyridoxine, or pyridoxal-5-phosphate). This vitamin has a long history of administration in diabetes and hyperglycemic conditions. It is especially effective in combination with vitamin B1 (thiamine), vitamin B2 (riboflavin) and vitamin B7 (biotin). Vitamin B6 doses...
  7. charlie

    P5P Recommendations

    I had someone recommend a good P5P supplement at one time but now I cannot find it. Would appreciate any recommendations of a good source, preferably affordable. :lol: :hattip
    • charlie
    • Thread
    • supplemental vitamin b6
    • Replies: 18
    • Forum: B6
  8. haidut

    Vitamin B6 For All Inflammatory Conditions And Cancer

    It looks like there is a strong push to patent derivatives of P5P for treatment of virtually all types of inflammatory conditions, and prevention of cancer. P5P even has anti-depressant and anti-seizure activities. The mechanism of action is antagonism of the P2X "receptors" and according to the...
  9. haidut

    ADHD may be simply a vitamin B6 deficiency symptom

    The study claims that multi-year adminstration of vitamin B6 completely "normalized" ADHD symptoms. It was a human study, so it should have even more weight / relevance. http://www.ncbi.nlm.nih.gov/pubmed/24321736 "...The disturbed activity of PLP dependent enzymes apparently forms those...
  10. haidut

    Vitamin B6 May Help Conditions Such As IBS / IBD And Chron's

    Unlike other posts I made recently, the study used the common/inactive form of B6 (the Hcl salt) and the human equivalent dosage was 25mg-30mg for human. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199223/
  11. haidut

    Vitamin B6 Is An Anticonvulsant

    The study used the activated form of B6 (pyridoxal-5-phosphate, P5P) and the human equivalent dosage was 500mg-600mg. The mechanism of action was the reduction of brain levels of glutamate via activation of glutamate dehydrogenase (GDH). http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317040/
  12. honeybee

    Vit B6 Progesterone and Prolactin

    I've been researching the B vits recently and came upon a few forums that support using b6 100-300 mgs daily for increasing progesterone (mainly fertility forums) and also for decreasing prolactin (mostly the weight ligfting forums). I have been supplementing b6 in hopes to lower prolactin, and...
    • honeybee
    • Thread
    • supplemental vitamin b6
    • Replies: 17
    • Forum: B6
  13. J

    P5P (a form of B6) Toxicity

    I found some people on the internet claiming they had neuropathy symptoms from the P5P form of vitamin B6, the one that's supposed to be safer. One used a coated tablet, other sublingual. Maybe some additives caused the problem, not the P5P. One claimed later B12 supplementation cured the...
    • j.
    • Thread
    • p5p supplemental toxicity vitamin b6
    • Replies: 24
    • Forum: B6
  14. J

    B6 And Dandruff

    This caught my attention: Source: ABSORPTION OF TOPICALLY APPLIED VITAMINS
  15. Bluebell

    Wow Had Great Effect From P5P Active Form Of B6

    I took some P5P, 50mg today and 50mg yesterday, with great effects. I have been struggling with neuropathy and body malaise. After taking the P5P the issues seemed to lift a bit and I felt more myself, more calm but energetic. I'm cautiously optimistic as often supplements are great to start...
    • Bluebell
    • Thread
    • p5p supplemental vitamin b6
    • Replies: 15
    • Forum: B6
  16. C

    Nature's Own Vitamin B1 and B6 Ingredients

    Nature's Own is a pretty big brand here in Australia. And from what's written on the bottle seemed like the best option for supplementing the B vitamins. I contacted them via a live chat on their site to ask about all ingredients--the chat was unresponsive but they emailed me a complete list...
  17. haidut

    The Dopamine Effects Of Vitamin B6 May Alleviate Diabetes

    Ray has written on the benefit of niacinamide in treating some cases of Type I diabetes, and I think I posted some studies in France where high dose niacinamide reversed early onset Type I diabetes in children. It looks like combining it with B6 may have additive effects...
  18. haidut

    Vitamin B6 May Be Anti-Adrenaline, And Thus Anti-Stress

    Stress-induced hypertension is also a common condition in an environment of constant strife. It seems that chronically elevated adrenaline is the main culprit in causing it, and drugs that lower adrenaline may be able to help. In case you can't get your hands on clonidine, you can try vitamin B6...
  19. haidut

    Vitamin B6 protects the gut from stress-induced damage

    Stress-induced ulcers are a common issue anywhere in the world where the environment is primed for instilling learned helplessness in people. It looks like vitamin B6 (again, the cheap pyridoxine hydrochloride salt) can help. Furthermore, it looks like B6 may have more general anti-stress action...
  20. haidut

    Vitamin B6 Is A Dopamine Agonist And Prolactin Inhibitor

    I mentioned in some of my other posts that vitamin B6, and especially the cheap pyridoxine hydrocholride type, was used several decades ago to treat hyperprolactinemia and dopamine deficiencies. The dosages used vary widely, but the lowest I have seen used is 10mg daily, while the highest was...
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