vitamin b6

Both human and animal studies. The human study was with pyridoxamine - a vitamin B6 isomer declared by FDA to be a "prescription drug" and as such banned for OTC sale in USA while still being widely available in most other countries. That FDA ruling is pointless due to the fact that pyridoxamine...

Pyridoxine, regardless of serotonin levels, increases production of 5-hydroxytryptophan in rat brain Background: The aim of this study was to evaluate effects of pyridoxine and butylated hydroxytoluene (BHT) on lipid peroxidation and on levels of 5-hydroxytryptophan and serotonin. Methods...

Does anyone know what kind of vitamins or minerals need to be supplemented (or need to be looking out for) when starting a high dose thiamin regiment? Today i started thiamin supplementation with thamine hcl (1.200 mg per day throughout the day) and sulbutiamine (200 mg) for trying to fix a...

To* Alright Did gear a few years back. Prolactin went really high during PCT, which caused issues for months after. 4 years on my libido is still low. I know dopamine is the issue because the peptide PT-141 temporarily fixed my problems for a few days. My prolactin is on the high range and...

Hi folks, I’d like to supplement P-5-P (the active form of vitamin B6), since I’ve read it could help with brain fog, focus, overall energy and motivation, by boosting dopamine production. I've seen also an interesting theory (TBH can't remember where) according to which P5P could also help...

The vitamin B6 paradox: Supplementation with high concentrations of pyridoxine leads to decreased vitamin B6 function. - PubMed - NCBI ↓ Full text The vitamin B6 paradox: Supplementation with high concentrations of pyridoxine leads to decreased vitamin B6 function. Vrolijk MF, et al. Toxicol In...

Our new product is finally here and it is "all about the ATP". I mentioned quite a few times on the forum and over email that we plan on releasing an ATP product and people have been asking me about it for the last few months. It seems a very simple task at first but we thought that we can do a...

Effect of pyridoxine on mice gastric ulcers and brain catecholamines after an immobilization stress. - PubMed - NCBI Ann Nutr Metab. 1992;36(5-6):313-7. Effect of pyridoxine on mice gastric ulcers and brain catecholamines after an immobilization stress. Henrotte JG1, Franck G, Santarromana M...

Hey guys, I'm interested in taking B6 for reducing prolactin, and also because I used to believe it'd reduce serotonin by shunting tryptophan into niacin (this is a claim made by Peat that has floated around the forums a few times). I have since found studies that found B6 to increase, rather...

..and can exacerbate a deficiency, especially in large amounts. Toxicity of Glycine for Vitamin B12-Deficient Chicks.† <- Crosses like this are scary. "Twenty-eight day-old White Leghorn chicks which had been fed the vito B12-deficient diet shown in Table I from the day of hatching were used...

Hello, I am from Holland. I have tested my blood and my vitamin B6 blood level is 345 mol/L. (Normal reference are 26-105) So this too much high. I took for two months Multivitamin with also Pyridoxine CHL 2.3 mg inside. I have weird/bizarre/lucid dreams at the moment and sleep...

Mitochondrial nutrients stimulate performance and mitochondrial biogenesis in exhaustively exercised rats. - PubMed - NCBI Abstract The aim of this study was to investigate the effects of a combination of nutrients on physical performance, oxidative stress and mitochondrial biogenesis in...

Is there any legitimate science out there that proves Pyroluria is a real condition? I've heard tons of people say they have it, but couldn't they just be having run-of-the-mill zinc deficiency symptoms because of high aldosterone/diet whatever? I'm especially interested if Dr. Peat has...

I guess this will be news to the people on the forum given the well-known anti-prolactin effects of vitamin B6. Anti-prolatin drugs are common therapy for Parkinson disease. What is surprising that the authors of the study did not consider that mechanism as explanation of the protective effects...

http://www.ncbi.nlm.nih.gov/pubmed/18791974 This study investigated the effect of vitamin B6 deficiency on the utilization and recuperation of stored fuel in physically trained rats. 48 rats were given either vitamin B6-deficient (B6-) diet or control (B6) diet for 4 weeks and were trained on...

B6 seems to have delayed my period. Can anyone explain the mechanism? I've been putting p5p powder in my foot baths pretty much every day for about 6 weeks or so. I'm not measuring, but it's probably 20-50mg. It's causing breakouts in odd places (behind ears and on neck). I thought it was...

I have posted a number of studies over the last year showing that vitamin B6 acts acts as an anti-adrenalin and anti-glucocorticoid. As these two substances are obviously elevated in conditions of stress, one might conjecture that controlling them with vitamin B6 would be desirable. I did not go...

I was wondering what might be good dosages of thiamine, riboflavin, niacinamide, pyridoxine, and biotin. I currently take the following and was wondering if the doses are OK: (I recently stopped for a few days then restarted as I find I feel better when I take them) thiamine 100mg riboflavin...

If I am reading this right, P5P acts like a PPI. This would explain some of the protective effects of P5P on stress-induced gastric ulcers in animals and men. http://www.jbc.org/content/263/8/3652.long "...Pig gastric membrane vesicles enriched in (H++K+)-ATPase were covalently modified with...

It seems vitamin B6 is especially important for the metabolism of long-chain fatty acids, which include the dreaded EPA, DHA, and arachidonic acids. The dosages of P5P that inhibited ACC-1 and ACC-2 in vitro are close to physiological and what is achievable by supplementation. Typical...