vitamin b1

  1. haidut

    Thiamine Is A Carbonic Anhydrase Inhibitor As Effective As Acetazolamide

    After findings the studies on synergism between thiamine and acetazolamide, and their combined use in a number of diseases I became intrigued. Then the wild thought just came out of nowhere - what if thiamine was also a carbonic anhydrase inhibitor but at different isoenzymes and with different...
    • haidut
    • Thread
    • acetazolamide carbonic anhydrase inhibitor study vitamin b1
    • Replies: 68
    • Forum: Scientific Studies
  2. haidut

    Acetazolamide Plus Thiamine Lower Serotonin And Tryptamine

    Another study showing beneficial effects of the combination acetazolamide + thiamine. The dose used was the same as the one for the schizophrenia study I posted earlier - 2g acetazolamide plus 1.5g thiamine spread into 3 daily doses. The decrease of tryptamine correlated well with improvement in...
    • haidut
    • Thread
    • serotonergic study tardive dyskinesia tryptamine vitamin b1
    • Replies: 7
    • Forum: Scientific Studies
  3. haidut

    Acetazolamide Plus Thiamine As Treatment Of Mental Conditions

    These studies confirm Ray's view that reduction in oxidative metabolism plays a role in the pathogenesis of these conditions. The combination should be a potent way to lower lactic acid beyond what either agent could do alone. I wonder if it could be a viable alternative to substances like DCA...
    • haidut
    • Thread
    • acetazolamide mental health study treatment vitamin b1
    • Replies: 36
    • Forum: Scientific Studies
  4. haidut

    Acetazolamide and thiamine combination lowers cortisol

    Human study in mental health patients. It looks like the drugs in combination have properties that neither one has alone. http://www.invenzone.com/research_paper ... -423699970 "...Several recent reports indicate that A + T administration may be beneficial for schizophrenia and tardive...
  5. M

    Dosing Strategies: Allithiamine, Benfotiamine, And B1

    I've been reading testimonials and studies about thiamine and its relationship to diabetes. Some studies really like benfotiamine for neuropathy and I can attest that after supplementing with about 600mgs a day of benfo I felt some of my symptoms abate nearly instantly, like the next day. I...
    • messtafarian
    • Thread
    • supplemental vitamin b1
    • Replies: 34
    • Forum: B1
  6. Bluebell

    Dosages Of Thiamine, Riboflavin, Niacinamide, Pyridoxine, And Biotin

    I was wondering what might be good dosages of thiamine, riboflavin, niacinamide, pyridoxine, and biotin. I currently take the following and was wondering if the doses are OK: (I recently stopped for a few days then restarted as I find I feel better when I take them) thiamine 100mg riboflavin...
  7. haidut

    Using Vitamins (thiamine) For Improving Glucose Control

    This is the second post of the series on vitamins for insulin resistance and glucose control. As you can see thiamine has highly beneficial effects on improving glucose oxidation and reducing the glycemic burden. The dosages from the animal and human trials are in the range 300mg-3,000mg daily...
    • haidut
    • Thread
    • supplemental vitamin b1
    • Replies: 17
    • Forum: B1
  8. haidut

    Thiamine Normalizes Pyruvate / Lactate Levels In Rats With Cancer

    Russian study, so I can't get the actual paper and see route of administration, but it was likely oral or intraperitoneal. Human equivalent dosage is 100mg - 150mg daily. http://www.ncbi.nlm.nih.gov/pubmed/664448
  9. haidut

    Thiamine Reduces Both Lactate And Ammonia

    The study was with humans and also included exercise, which makes thiamine even more interesting to athletes. The type of thiamine used was TTFD, which is the scientific name for allithiamine, and the dose was 10mg/kg. That would mean a total daily dose in the range of 600mg-900mg for most...
  10. K

    Body Odor From B1

    I think I discovered the source of my body odor... I think it's from B1. I started B1 (initially as benfotiamine, and then switched to regular B1) in late May and some time in spring or maybe early summer I started to smell funky. I switched from NDT to synthetics around June or so, and I...
    • Katty
    • Thread
    • supplemental vitamin b1
    • Replies: 22
    • Forum: B1
  11. haidut

    Thiamine Reverses Diabetic Kidney Damage In Humans

    The study used what they consider a "high" dose of 300mg thiamine and duration was 3 months. In 35% of the patients the damage disappeared completely. http://www.sciencedaily.com/releases/20 ... 092149.htm http://www.drwhitaker.com/benefits-of-v ... ur-kidneys "...In a double-blind...
  12. haidut

    Thiamine (B1) may reduce PUFA content in cells

    The study was not on human cells, but it quotes several other studies showing similar effects so it would be interesting to dig more into this. Thiamine also reduced total lipid content, not just PUFA levels, which could be an added benefit. http://www.ncbi.nlm.nih.gov/pubmed/856287 "...The...
  13. managing

    Thiamine Pyrophosphate (Benfotiamine)

    Experiences, thoughts, studies? I can't find RP addressing specifically. Pyrophosphate is key in osteblast activity, but not sure if it makes it to the bones intact?
    • managing
    • Thread
    • supplemental vitamin b1
    • Replies: 5
    • Forum: B1
  14. haidut

    Thiamine Acts Similarly To DCA And May Be Helpful In Cancer

    Ray wrote in one of his last newsletters that some pharma companies are working hard on drugs that can do one of two things - stimulate pyruvate dehydrogenase or inhibit pyruvate dehydrogenase kinase. DCA is known to do the latter and that is the commonly described mechanism behind its...
  15. K

    B1 Calf Cramping

    I started B1 (benfotiamine) about 3-4 weeks ago. I'm taking 80mg one time a day. Had some decent responses (sleeping a little better, a little warmer, skin a little better). However, I've noticed some calf cramping the past 2 weeks or so. It's not painful, but feels like mild pinches or...
    • Katty
    • Thread
    • cramps supplemental vitamin b1
    • Replies: 5
    • Forum: B1
  16. K

    Sulbutiamine

    I know peat mentioned B1 for boosting brain energy. I found this information from wikipedia about Sulbutiamine quite interesting. This is a derivative of thiamin that passes the blood brain barrier more rapidly. Sulbutiamine is a lipophilic molecule that crosses the blood–brain barrier more...
    • Kasper
    • Thread
    • supplemental vitamin b1
    • Replies: 23
    • Forum: B1
  17. Vinero

    Thiamine, histamine, and hypothermia

    It seems that a thiamine deficiency, also known as vitamin B1, can have some undesirable consequences such as: -Increased histamine levels: http://link.springer.com/article/10.1007%2FBF01997372 -Low body temperature: http://www.ncbi.nlm.nih.gov/pubmed/2090843 Haidut already posted studies about...
    • Vinero
    • Thread
    • supplemental vitamin b1
    • Replies: 3
    • Forum: B1
  18. haidut

    Surrogates For Thyroid Hormone

    This post is directed at those who have issues with large doses of caffeine. For a long time caffeine caused me to have "jitters", even when taken with enough sugar. Recently I was reading on the design of the RedBull energy drink and how taurine was added to mitigate the caffeine "jitters"...
  19. C

    Nature's Own Vitamin B1 and B6 Ingredients

    Nature's Own is a pretty big brand here in Australia. And from what's written on the bottle seemed like the best option for supplementing the B vitamins. I contacted them via a live chat on their site to ask about all ingredients--the chat was unresponsive but they emailed me a complete list...
  20. haidut

    Thiamine For Hashimoto Disease

    This is a continuation of the studies on thiamine I posted several weeks ago. It's from the same researchers, and in fact this one was sent to me by the lead scientist without me asking for it. I think they are excited to see some interest in their studies on thiamine. Hashimoto Disease seems to...
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