uncoupler

  1. haidut

    Lanosterol - Liquid Lanosterol For Lab/R&D

    I guess most people on the forum who have heard of lanosterol know it in the context of treating cataracts. Lanosterol - Wikipedia There is a company out there who used to sell lanosterol as eye drops and it is insanely expensive - $100 for a meager 10mg lanosterol. Anyways, lanosterol is...
  2. haidut

    Methylene Blue (MB) Uncouples Respiration

    This was an in-vitro study, but knowing the effects of MB in vivo makes it very plausible that MB is indeed a respiration uncoupler similar to DNP. http://www.sciencedirect.com/science/ar ... 9397007679 "...In tightly coupled, succinate-respiring mitochondria, addition of MB resulted in an...
  3. haidut

    Aspirin Comparable To DNP As Mitochondrial Uncoupler

    This image is from the study I posted on the effects of aspirin on GI tract. As you can see from the attached image, aspirin increased mitochondrial respiration by 300% while DNP increased it by 400%. However, the authors stated that this concentration of DNP is not safe and in reality most...
  4. haidut

    Caffeine stimulates electron flow, may uncouple respiration

    The drug used was a caffeine salt but in the body it is metabolized to caffeine and sodium benzoate, so the effects are pretty much like those of caffeine. The concentration used (6microM - 60microM) corresponds to in vivo human dose of 30mg-300mg. http://www.ncbi.nlm.nih.gov/pubmed/7456349...
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