• tca300: I understand this is off topic from what you typically teach, but I was wondering if you have run across any information or learned on your own, things that help people grieve over lost loved ones, and or fear of losing others to death? Thank you!

    Ray Peat: It activates the “helplessness” reactions in the body, stress weakening your own life, and I think it can help to get out of that if you think of your life as a continuation of theirs—the same life, though with fewer bodies.

    Rest in Paradise, Raymond Peat  October 12, 1936 - November 24 2022

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uncoupler

  1. haidut

    Lanosterol - Liquid Lanosterol For Lab/R&D

    I guess most people on the forum who have heard of lanosterol know it in the context of treating cataracts. Lanosterol - Wikipedia There is a company out there who used to sell lanosterol as eye drops and it is insanely expensive - $100 for a meager 10mg lanosterol. Anyways, lanosterol is...
  2. haidut

    Methylene Blue (MB) Uncouples Respiration

    This was an in-vitro study, but knowing the effects of MB in vivo makes it very plausible that MB is indeed a respiration uncoupler similar to DNP. http://www.sciencedirect.com/science/ar ... 9397007679 "...In tightly coupled, succinate-respiring mitochondria, addition of MB resulted in an...
  3. haidut

    Aspirin Comparable To DNP As Mitochondrial Uncoupler

    This image is from the study I posted on the effects of aspirin on GI tract. As you can see from the attached image, aspirin increased mitochondrial respiration by 300% while DNP increased it by 400%. However, the authors stated that this concentration of DNP is not safe and in reality most...
  4. haidut

    Caffeine stimulates electron flow, may uncouple respiration

    The drug used was a caffeine salt but in the body it is metabolized to caffeine and sodium benzoate, so the effects are pretty much like those of caffeine. The concentration used (6microM - 60microM) corresponds to in vivo human dose of 30mg-300mg. http://www.ncbi.nlm.nih.gov/pubmed/7456349...
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