• Due to excessive bot signups along with nefarious actors we are limiting forum registration. Keep checking back for the register link to appear. Please do not send emails or have someone post to the forum asking for a signup link. Until the current climate changes we do not see a change of this policy. To join the forum you must have a compelling reason. Letting us know what skills/knowledge you will bring to the community along with the intent of your stay here will help in getting you approved.

uncoupler

  1. haidut

    Lanosterol - Liquid Lanosterol For Lab/R&D

    I guess most people on the forum who have heard of lanosterol know it in the context of treating cataracts. Lanosterol - Wikipedia There is a company out there who used to sell lanosterol as eye drops and it is insanely expensive - $100 for a meager 10mg lanosterol. Anyways, lanosterol is...
  2. haidut

    Methylene Blue (MB) Uncouples Respiration

    This was an in-vitro study, but knowing the effects of MB in vivo makes it very plausible that MB is indeed a respiration uncoupler similar to DNP. http://www.sciencedirect.com/science/ar ... 9397007679 "...In tightly coupled, succinate-respiring mitochondria, addition of MB resulted in an...
  3. haidut

    Aspirin Comparable To DNP As Mitochondrial Uncoupler

    This image is from the study I posted on the effects of aspirin on GI tract. As you can see from the attached image, aspirin increased mitochondrial respiration by 300% while DNP increased it by 400%. However, the authors stated that this concentration of DNP is not safe and in reality most...
  4. haidut

    Caffeine stimulates electron flow, may uncouple respiration

    The drug used was a caffeine salt but in the body it is metabolized to caffeine and sodium benzoate, so the effects are pretty much like those of caffeine. The concentration used (6microM - 60microM) corresponds to in vivo human dose of 30mg-300mg. http://www.ncbi.nlm.nih.gov/pubmed/7456349...
Top