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Brown adipose tissue (BAT) is the primary site of adaptive thermogenesis, which is involved in energy expenditure and has received much attention in the field of obesity treatment. By screening a small-molecule compound library of drugs approved...
It has long been shown that T3 increases uncoupling ,but this study shows that it also works vice versa :
Uncoupling (through BAT activation) increases deiodinase type 2 ,which catalyzes T4 toT3 conversion .
This should create a positive feedback loop. If you uncouple your metabolism with...