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  1. J

    TUDCA effect!!! Maybe TMI...

    Holy Jebus, what is happening? I took 1/4 of a 250mg Nutricost TUDCA pill and it flipped my insides out. Due to my ill health and poor gut microbes/SIBO, I could go 4 days without a bowel movement and even after that I would need the assistance of Magnesium oxide or bisglycinate. I took the...
  2. J


    Can anyone be so kind to tell me if TUDCA is alkaline in nature once in the stomach. I had a terrible reaction to Bile salts because my stomach is so alkaline and caused my SIBO/Candida to blow up. The reason for the SIBO is because my digestive system is a mess after going through long term...
  3. A

    FDA advisers narrowly side against an experimental ALS drug

    https://www.nytimes.com/2022/03/30/health/als-treatment-amx0035.html By a narrow margin, a federal panel of independent medical experts concluded Wednesday that there is not yet enough evidence that an experimental therapy for amyotrophic lateral sclerosis, commonly known as A.L.S., is effective...
  4. Drareg

    TUDCA and phenylbutyric acid accelerate thyroid hormone activation and energy expenditure

    Interesting study, combining both substances should have a positive effect. 21237159 Exposure of cell lines endogenously expressing the thyroid hormone activating enzyme type 2 deiodinase (D2) to the chemical chaperones tauroursodeoxycholic acid (TUDCA) or 4-phenylbutiric acid (4-PBA) increases...
  5. A

    Reversal of alopecia areata and osteoporosis by activation of bile acid receptor

    Alopecia areta (AA) is one of the most common immune diseases characterized by a chronic inflammatory reaction to hair follicles [1,2]. The lifetime incidence of AA is approximately 2% worldwide, and there was no significant difference between the sexes. Alopecia areata is an autoimmune disorder...
  6. A


    https://hackyourgut.com/2016/11/03/10-reasons-why-people-with-sibo-should-care-about-bile Small intestinal bacterial overgrowth (SIBO) is commonly found in people with IBS. The small intestine houses a miniscule number of bacteria when compared to the colon. When bacteria overgrow in the small...
  7. fever257

    Huge step in gallbladder function w/ TUDCA - now what?

    Hey everyone, So I think I'll consider this an update to my last major post: Please Help: Endotoxin Overload & Post-parasite Gut Disaster . In this post, I described my persistent and near-debilitating gut issues. I long suspected the issue was rooted in some kind of dysbiosis / SIBO issue. I...
  8. Lokzo

    ?TUDCA: The Holy Grail For Liver Health?

  9. Sefton10

    Successful protocol for viral/fungal issues and vertigo/tinnitus

    I wanted to post this in case there is value in it for others experiencing similar issues. In recent months I have been really struggling with what I suspected to be Ménière’s disease or Labyrinthitis. Symptoms were a constant feeling of vertigo/dizziness that would flare up in acute attacks...
  10. ImprovingDaily

    Anyone Have Personal Experience With TUDCA?

    I'm thinking about trialing a round of TUDCA. I have noticed benefits from Taurine and I know this has Taurine in the molecule. I also still have issues with coffee, so I'm assuming I still have issues with my liver along with still feeling like I have issues with estrogen. What kind of dosages...
  11. michael94


    decreases rates of lipid peroxidation http://www.ncbi.nlm.nih.gov/pubmed/9655521 interesting mice study demonstrating some coool effects http://www.ncbi.nlm.nih.gov/pubmed/26681941 neuroprotective too http://www.ncbi.nlm.nih.gov/pubmed/26379056 May be something worth trying if you...
  12. michael94

    Tudca May Be Of Interest To Us? Interesting Research

    http://www.ncbi.nlm.nih.gov/pubmed/24891994 (From the abstract ) Feel free to offer your thoughts I'm currently working through the full free text available here: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030606/