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Dear Carnivore Dieters, A Muscle Meat Only Diet is Extremely Healing Because it is a Low "vitamin A" Diet. This is Why it Works so Well...
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Pregnenolone Is A Potent (functional) Endotoxin (TLR4) Antagonist
It seems that pregnenolone is finally starting to look exciting to the medical industry. In addition for its intensive studies for a variety of mental issues, now studies are coming out demonstrating its endotoxin (LPS) antagonism effects. As most forum users know, endotoxin exerts its effects...- haidut
- Thread
- alcoholism allopregnanolone alzheimer's antagonist cvd depression endotoxin epilepsy immune system inflammation lps ms multiple sclerosis pregnenolone ptsd schizophrenia sepsis tlr4 tnf
- Replies: 10
- Forum: Scientific Studies
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Endotoxin (and Baby Formula) May Be The Cause Of IBD And Brain Damage
It is a well-publicized fact that people with inflammatory bowel disease (IBD) such as Crohn's and ulcerative colitis (UC) struggle with severe cognitive and mood issues. They are also at a much greater risk of developing dementia than the general population, and at a much younger age too...- haidut
- Thread
- baby formula brain damage cognitive impairment crohn's endotoxin formula ibd inflammatory bowel disease lps mental illness nec necrotizing enterocolitis stress tlr4 uc ulcerative colitis
- Replies: 29
- Forum: Scientific Studies
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“NO” To Autophagy: Fat Does The Trick For Diabetes
“NO” to Autophagy: Fat Does the Trick for Diabetes During the progression from obesity to diabetes, a critical attribute is inability to maintain metabolic homeostasis under excessive energy and nutrient exposure, which triggers insulin resistance. Intensive research efforts have linked chronic...- paymanz
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- autophagy diabetes hyperinsulinemia inflammation insulin insulin sensitivity mitophagy nitric oxide obesity tlr4
- Replies: 0
- Forum: Articles & Scientific Studies
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Saturated Fat (palmitate) Does NOT Activate TLR4
We must have had hundreds of discussions on this topic on the forum. Some forum users strongly believe that saturated fat (SFA) increases inflammation by binding to and activating the endotoxin (LPS) receptor TLR4. Among all SFA, palmitate is the one most commonly blamed and has been...- haidut
- Thread
- disease endotoxin inflammation jnk lps obesity palmitate palmitic acid saturated fat sfa tlr4 vindicated
- Replies: 28
- Forum: Scientific Studies
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The Benefits Of Fasting Are Due To Lowering Endotoxin (LPS), Not Less Calories
As many of you know, the argument for/against fasting has been raging on the forum for several years at this point. While Ray has spoken several times favorably about potentially skipping a meal or two, he has repeatedly said that chronic fasting is not something he recommends due to its...- haidut
- Thread
- antagonist benefits caloric restriction cr diabetes endotoxin fasting inflammation lps microbiome obesity tlr4
- Replies: 39
- Forum: Scientific Studies
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Endotoxin Causes (liver) Steatosis, Insulin Resistance And Atherosclerosis
I know this study was in hepatitis C patients only, but there is nothing about Hep C that would invalidate this finding in the general population too. Quite a few people on the forum reported that when they tried to talk to their doctor about endotoxin and its possible role in their health...- haidut
- Thread
- atherosclerosis cvd endotoxemia endotoxin hepatitis inflammation insulin resistance liver lps steatosis tlr4
- Replies: 16
- Forum: Scientific Studies
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Pulmonary Fibrosis May Be Caused By Endotoxin (LPS)
Ray spoken and written at length about endotoxin (LPS) and its role in virtually all chronic conditions. Mianstream medicine vehemently denies that LPS is an issue, except possibly for people with liver disease. But in thoses cases, the claim is that endotoxin may cause fever and diarrhea but...- haidut
- Thread
- endotoxin fibrosis inflammation lps pulmonary fibrosis scleroderma systemic sclerosis tlr4
- Replies: 9
- Forum: Scientific Studies
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Osteoarthritis (OA) Is Driven By Endotoxin, Can Be Completely Reversed
Unlike rheumatoid arthritis (RA), its "cousin" known as osteoarthritis (OA) is not generally believe to be due to chronic inflammation. The official cause of OA is "unknown" (just like RA) but often cited factors include genetics, excess weight, and advanced age. The study below points the...- haidut
- Thread
- arthritis endotoxin gut permeability inflammation lipopolysaccharide lps osteoarthritis prebiotic tlr4
- Replies: 4
- Forum: Scientific Studies
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Pancreatic Cancer Driven By Bacteria/endotoxin; Antibiotics Can Prevent/treat
I just posted a seminal study showing that possibly ALL autoimmune conditions may be caused by a chronic low-grade infection. This infection stems from a gut bacteria, which has translocated from the gut to the liver/lymphs due to compromised gut barrier and lingers there chronically thus...- haidut
- Thread
- ampicillin antibiotics bacteria bifidobacterium cancer cause endotoxin gut gut permeability lps microbiome pancreas pancreatic cancer tlr tlr4 tlr6 translocation
- Replies: 15
- Forum: Scientific Studies
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Serotonin/endotoxin/PUFA As Primary Causes Of Depression And Diabetes; Can Be Easily Blocked
This is one of the unique studies that breaks away from the mainstream dogma that serotonin is the "happy hormone" and increasing it with drugs like SSRI can lead to nothing but goodness. The study not only directly states that past/current SSRI use is a risk for developing diabetes but show how...- haidut
- Thread
- 5-ht 5-ht3 5-htt diabetes endotoxemia endotoxin inflammation liver disease lps obesity pufa serotonin serotonin transporter sert tlr4
- Replies: 45
- Forum: Scientific Studies
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Without Endotoxin (TLR4), An HIV Infection May Not Cause AIDS
More than 3 years ago I posted a study showing that monkeys that are natural carriers of the simian version of HIV known as SIV, do not develop AIDS. It was only after being injected with endotoxin (even when attenuated) that these monkeys develop the wasting syndrome and oppostunistic...- haidut
- Thread
- aids diet endotoxin hiv infection inflammation lps siv tlr4 wasting syndrome
- Replies: 24
- Forum: Scientific Studies
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Endotoxin (from Low-grade Infection) As A Cause Of Crohn's, UC, And Other IBD
Not sure how many people on the forum know that Crohn's disease, which is a type of an inflammatory bowel disease (IBD), has recently been reclassified in some countries as infectious of origin and not as an autoimmune disease. The causative pathogen of Crohn's is thought to be a type of...- haidut
- Thread
- alkaline phosphatase bacteria crohn's endotoxin ibd infection recurring tlr4 uc ulcerative colitis
- Replies: 69
- Forum: Scientific Studies
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SSRI Drugs (Prozac) Worsen Prenatal Stress And May Contribute To Autism
I am posting this study because it may explain why the incidence of autism is much higher in male than in female offspring. As I posted in a few other threads before, serotonin is one of the likely direct causes of the autism pathology and it is of course elevated during chronic stress...- haidut
- Thread
- autism endotoxin exacerbate fluoxetine lps prenatal prozac serotonin ssri stress tlr4 worsen
- Replies: 3
- Forum: Scientific Studies
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The Brain Damage In Cases Of TBI May Be Partially Driven By Gut Bacteria
Traumatic brain injury (TBI) is one of the most common injuries sustained by soldiers on the battleield, as well as by various athletes (NFL, NHL, major league soccer, etc). Repeated TBI events or even a single TBI of sufficient severity can trigger what is commonly known as chronic traumatic...- haidut
- Thread
- cte endotoxin exacerbate gut flora gut permeability infection inflammation microbiome tbi tlr4
- Replies: 1
- Forum: Scientific Studies
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Endotoxin (LPS) Theory Of Atherosclerosis (CVD)
I posted a study more than year ago, which examined the role of NO in aging and disease. The Nitric Oxide (NO) Theory Of Aging One of the main endogenous stimulators of NO synthesis is endotoxin (LPS). It turns out that the connection between LPS and CVD has been studied for a long time in...- haidut
- Thread
- atherosclerosis causative cvd diabetes endotoxin inflammation insulin resistance lps obesity stress stroke tlr4
- Replies: 24
- Forum: Scientific Studies
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Lanosterol - Liquid Lanosterol For Lab/R&D
I guess most people on the forum who have heard of lanosterol know it in the context of treating cataracts. Lanosterol - Wikipedia There is a company out there who used to sell lanosterol as eye drops and it is insanely expensive - $100 for a meager 10mg lanosterol. Anyways, lanosterol is... -
Alcohol "addiction" Driven By Endotoxin (TLR4)
I posted a few threads in the past about addiction, and especially alcohol addiction being driven by high cortisol and low dopamine. This new study adds more pieces to the puzzle by implicating endotoxin in that process as well. Just as importantly, the study found that the desire to drink...- haidut
- Thread
- alcohol alcoholism curb cure drinking endotoxin naltrexone tlr4 treat
- Replies: 46
- Forum: Scientific Studies
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Candida Overgrowth Is A Major Factor In (alcoholic) Liver Damage / Cirrhosis
Over the last 5 years or so it has become very fashionable among many "naturopaths" to throw the diagnosis "Candida overgrowth" at every symptom of gut dysfunction people present with at the doctor. Peat has spoken about Candida overgrowth and how the fungus typically only becomes an issue in...- haidut
- Thread
- alcohol candida cirrhosis endotoxin glucans inflammation intestinal permeability liver disease lps tlr4
- Replies: 42
- Forum: Scientific Studies
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Endotoxin (LPS) Is The Cause Of Venous Malformations In The Brain (CNS)
As a former athlete I am keenly aware of the several conditions that are known to have much higher incidence in (even very young) athletes. Aside from cardiac arrest and kidney damage, other conditions with higher incidence in athletes include aneurysms and various other vascular disorders in...- haidut
- Thread
- aneurysm antibiotic brain ccm cerebral cavernous malformation endotoxin lps microbiome tlr4
- Replies: 10
- Forum: Scientific Studies
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Blocking The Endotoxin (TLR4) Receptor May Protect From Ebola Lethality
The connection between the "flu" and endotoxin has been explored at length by Peat. However, recent evidence has accumulated that quite a few other viruses and the terrible infections they cause may me mediated either by the endotoxin load they increase or by the viruses themselves activating...- haidut
- Thread
- antagonist ebola endotoxin infection lps therapeutic tlr4 virus
- Replies: 4
- Forum: Scientific Studies