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I know the topic of weed is controversial but by now the link between heavy and chronic marijuana use and the risk of psychotic conditions like schizophrenia has been well established. Peat mentioned a few times briefly that cannabis has anti-androgenic effects and should not be used chronically...
r J Pharmacol. 1976 Feb;35(2):309-13.
Antitussive activity of some naturally occurring cannabinoids in anesthetized cats.
Gordon R, Gordon RJ, Sofia D.
Experimental cough was elicited in pentobarbital-anesthetized cats by either electrical stimulation of the superior laryngeal nerve...