suppression

  1. haidut

    Pregnenolone (P5) Fully Prevents Testicular Atrophy Due To Steroid (ab)use Or High Estrogen

    I often get emails from bodybuilders, athletes and others who have used or currently use steroids and want to either protect themselves while using those steroids or want to recover after long-term usage. It is well-known that most performance enhancing steroids, including plain testosterone (T)...
    • haidut
    • Thread
    • atrophy estradiol estrogen gonads ovaries p5 pregnenolone suppression testicles testosterone
    • Replies: 86
    • Forum: Scientific Studies
  2. haidut

    Estrogen And Cortisol, Not Androgens, Suppress Immunity

    There is a very famous theory in reproductive biology still considered the dominant one in its field. Namely, males have to accept a trade-off between androgen levels and immunity. It is known as the immunocompetence handicap hypothesis (ICHH). Higher androgen levels, the theory goes, allow the...
    • haidut
    • Thread
    • aging androgen aromatase inhbitor atrophy cortisol dhea disease estrogen immunity progesterone suppression thymus
    • Replies: 1
    • Forum: Scientific Studies
  3. haidut

    PUFA Are Immunosuppressive, Fasting And Protein Restriction (possibly) Even More So

    Several great studies, which quickly illustrate the connection between PUFA, immune system, estrogen, cortisol, cancer and the protective role vitamin A/E play as well as their likely mechanism(s) of action. As I mentioned on one of the first podcasts with Danny Roddy, the role of PUFA as...
    • haidut
    • Thread
    • aging cancer disease fat immune system immunity inhbition pufa suppression toxic
    • Replies: 0
    • Forum: Scientific Studies
  4. Peatogenic

    Long-term Androsterone

    I feel that Androsterone has been a wonder drug for me, offering benefits to my mental health, strength, youthfulness, and libido. It seems to also have a toning effect on my body, removing excess water in face, chest, etc. My erections are also stronger. Definitely increased appetite I...
  5. haidut

    DHEA As A Cure For Cancer

    A fascinating study, which highlights once again not only the role of one of the "youth" steroids in human health but also demonstrates that the protective/therapeutic mechanisms of DHEA against cancer are due to increase in metabolism and ROS generation. The primary restrictive mechanism on ROS...
    • haidut
    • Thread
    • cancer cure dhea dhea-s g6pd g6pdh metabolism ros suppression treatment tumor
    • Replies: 63
    • Forum: Scientific Studies
  6. haidut

    Niacinamide Is Anti-estrogenic

    Yet another strong point for niacinamide. I am beginning to wonder if there is any condition or biomarker of disease that niacinamide cannot affect. Peat has written many times about the sirtuin genes and their promoter resveratrol. While there is already quite a bit of evidence that SIRT1...
    • haidut
    • Thread
    • antagonist estrogen fulvestrant hdac inhibition niacinamide sirt1 sirtuins study suppression
    • Replies: 36
    • Forum: Scientific Studies
  7. haidut

    Probiotics Powerfully Suppress The Immune System

    The article is actually kind of interesting in regards to the new HIV therapies being tried out. But what caught my eye is specifically this quote: http://www.aidsmap.com/Novel-immune-sup ... ge/2902377 http://journal.frontiersin.org/Journal/ ... 7/abstract "...The vaccine consisted of...
  8. haidut

    Casein Is A Potent Tumor Suppressor

    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507493/ "...Here, we identified the milk protein α-casein as a novel suppressor of tumor growth and metastasis. Briefly, Met-1 mammary tumor cells expressing α-casein showed a ~5-fold reduction in tumor growth and a near 10-fold decrease in...
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