stress

  1. Geronimo

    Stress Dysregulates Lung Function

    Anger, stress, dysregulation produces wear and tear on the lung How stress influences disease: Study reveals inflammation as the culprit I think we can all piece this together here.
  2. haidut

    Low Metabolism, Cellular Debris May Cause Huntington Disease (HD)

    Yet another study demonstrating the crucial role of oxidative metabolism (OXPHOS) in a chronic degenerative condition considered largely genetic in origin. Just as importantly, the study corroborates findings from other recent reports/experiments demonstrating that the presence of cellular...
  3. haidut

    Prenatal Stress Ups Serotonin, Which Causes Autism And Mental Disease In Offspring

    Another good study, which not only corroborates the causative role of elevated serotonin in a number of behavioral disorders in children (which extend into adulthood) but demonstrates the key role of endotoxin (LPS) in that process. Namely, the pregnant animals exposed to stress who had sterile...
  4. ScurveDream

    Money/finances To Achieve Health -- Or Health First To Then Achieve It?

    Seems a tough method forward for people. Some pursue resources and funds so they can reach a place of health or "betterment" of sorts -- others try and achieve "salvation" of some sort even with nothing but the clothes on their backs (if even). What approach usually is the more optimal one...
  5. ScurveDream

    Long Chins, Big Ears, Long/narrow Faces = GH, Estrogen?

    I notice some feature mix ups and combinations. Guys with stronger jaws (not sure about women though) tend to have larger ears, but there are guys with big ears and longer chins (downward protruding more than forward) that lack the same jaw types and facial broadness. Since the effects of GH...
  6. ScurveDream

    DHEA Or Pregnenolone To Combat Possible Caffeine-induced Stress?

    My bad if this has been spoken of here specifically since a quick glance of some terms did not give an immediate impression that it was. Basically, can something like DHEA and/or pregnenolone lessen/dampen the possible stress response from caffeine use? I read a lot here and on Ray's...
  7. haidut

    Reducing Stress May Reverse Greying Of Hair

    Just a few weeks ago I made a post about yet another study linking grey hair to increased stress. The mechanism of action described in that study was increased HPA activity and specifically elevated norepinephrine levels. Other studies have also implicated tryptophan/serotonin, which is still...
  8. haidut

    Long Work Hours Linked To Hypothyroidism

    The connection between stress and health issues is perhaps the best kept "public secret". As the saying goes, the only people who do not believe in the pathology of stress are doctors...and the dead. I would add to this category the profession of statisticians who publish studies like the one...
  9. haidut

    Stress Causes Grey Hair

    Not exactly news for most of my readers, but it is a popular topic for many people and, as usual, the response of most doctors is that the premature greying is genetically influenced and not much can be done about it. While the study below conclusively links greying to stress, I think the...
  10. haidut

    The Government Knows Stress Causes "learned Helplessness" / Depression

    I have had discussions with numerous psychiatrists about the concept of "learned helplessness" (LH) and its relation to chronic stress. All of those doctors flatly denied that LH is a concept relevant to humans and argued that it is nothing more than a useful model of depression in animal...
  11. haidut

    COVID-19/SARS May Be Due Simply To Serum PUFA And Its Peroxidation

    During the last podcast with Danny Roddy, Dr. Peat and I discussed the role of elevated free fatty acids (FFA) in the blood as facilitators of viral infection. I opined that the hydrophilic nature of PUFA circulating in the blood increases the permeability of cells and allows for easier viral...
  12. haidut

    Studies In Animals Often Use Stressful Methods That Produce Invalid Results

    Back in 2012, when I first started writing about the benefits of steroids such as pregnenolone, I often got emails quoting the study below as evidence that pregnenolone and related steroids amplify instead of mitigate the stress response (HPA axis). Neuroactive steroids modulate HPA axis...
  13. haidut

    Stress (cortisol) Can Cause ANY Autoimmune Condition By Disrupting Gut Barrier

    A great new study that is not afraid to point out the paradox between mainstream medicine's claims of beneficial effects of cortisol and the reality of "autoimmune" conditions more often than not being associated with elevated levels of CRH, ACTH and cortisol. The role of CRH as a causative...
  14. haidut

    How Chronic Stress (cortisol) Causes Disease

    Back in 2018 I did a post on a neat study that demonstrated how the presence of cellular (mitochondrial) fragments in the blood stream acts identically to the pituitary hormone ACTH and as such activates the HPA axis. The more cellular fragments are in the bloodstream the more intense the stress...
  15. haidut

    Long Work Hours (stress) At The Office Cause Hypertension And CVD

    Many of my readers surely are familiar with the saying "work hard, play hard". This mantra is at the core of the psychotic work culture of most "developed" countries and despite the assurances of doctors and public health officials that bad health is largely due to "bad luck" (e.g. genes) the...
  16. haidut

    Almost 40% Of Military Women (and Even More Military Males) Are Infertile

    I think this study should dispel some of the myths about what being "fit" really means, and that being truly healthy or "fit" often are quite divergent paths. Infertility is actually one of the most reliable indicators of poor systemic health and predictor of future chronic disease (in both...
  17. haidut

    Serotonin Causes Anhedonia. And Mental Illness In General

    As many of my readers know, anhedonia is one of the most pernicious symptoms of most mental disorders, and is perhaps the most resistant to therapy. It also happens to be one of the main triggers of attempted suicide, based on interviews with suicide survivors. I posted some threads in the past...
  18. haidut

    Down Syndrome (DS) Cognitive Handicap Is Due To (cellular) Stress, May Be Reversible

    If there is any disease that is currently considered incurable even in principles, it likely comes from the group of inherited/genetic disorders. Perhaps the most well-known one, due to rapidly rising incidence and thus publicity, is DS. Perhaps its most disabling aspect of DS is the cognitive...
  19. haidut

    Rats Can Drive Cars (to Lower Stress), Befriend Robot Rats And Help Them When In Trouble

    Official/pathological science keeps sternly warning us not to anthropomorphize and to think of animals as nothing but dumb, soul-less automatons. Yet, there has been no evidence discovered in over 100 years of pathological science reign to support such a view. To the contrary, the studies below...
  20. haidut

    SFA / MUFA Are Preferentially Oxidized, While PUFA Are Stored/accumulated

    Just a quick post in response to some of the hate mail I keep getting on a daily basis in regards to the body's discriminatory treatment of various fat types. According to various proponents of keto diets, fasting, etc the organism has no preference for one type of fat or another in terms of...
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