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My bad if this has been spoken of here specifically since a quick glance of some terms did not give an immediate impression that it was.
Basically, can something like DHEA and/or pregnenolone lessen/dampen the possible stress response from caffeine use?
I read a lot here and on Ray's...
article of september 2019:
Bone, not adrenaline, drives fight or flight response
When faced with a predator or sudden danger, the heart rate goes up, breathing becomes more rapid, and fuel in the form of glucose is pumped throughout the body to prepare an animal to fight or flee.
These...
Just weeks after the first study on the link between elevated estrogens (all types) and autism, a new study again demonstrated a link between elevated maternal estrogen (estradiol in this case) and risk of offspring autism...
A Fall in Plasma Free Fatty Acid (FFA) Level Activates the Hypothalamic-Pituitary-Adrenal Axis Independent of Plasma Glucose: Evidence for Brain Sensing of Circulating FFA
Endocrinology. 2012 Aug; 153(8): 3587–3592.
Published online 2012 Jun 1. doi: 10.1210/en.2012-1330
PMCID: PMC3404348...
One of the more controversial of Ray's statements is that chronic stress is the underlying cause of many/most chronic conditions, especially autoimmune ones. In several of his articles he describes the role tissue damage under the influence of cortisol and estrogen play in creating an immune...
Almost two years ago I posted a study showing that PUFA can stimulate cortisol release even in the absence of ACTH.
Pufa Stimulates Cortisol Production Even In The Absense Of Acth
However, that study above did not look at the effects of saturated fatty acids (SFA) and I keep getting emails...
Mitochondria affect stress responses
Cell's powerhouse plays role in mind-body interactions, with long-term health effects
Wallace postulates that the current study indicates that an important reason for our limited progress in understanding the genetic and biologic basis of psychology is our...
Sounds like a fairly obvious conclusion, but up until about 5 years ago mainstream medicine claimed that loneliness had no impact on our health. The key finding here is that loneliness upregulates BOTH norepinephrine and cortisol levels - i.e. triggers the stress response, especially in the...
Event the people who find that caffeine gives them a "stress response" or raises their blood pressure, cortisol, etc should be able to quickly adapt. This study shows complete adaptation to all parameters of the "stress response" induced by 250mg caffeine daily. The adaptation occurred in as...
Increased serotonin transporter gene (SERT) DNA methylation is associated with bullying victimization and blunted cortisol response to stress in childhood: a longitudinal study of discordant monozygotic twins.
Bullied twins had higher SERT DNA methylation at the age of 10 years compared with...
It is well known that clonidine lowers adrenalin, and Ray has written about it. It looks like clonidine is also able to restrain the other side of the sympathetic stress response - the ACTH, cortisol, hyperglycemia process. All studies below are in humans. So, it looks like clonidine may be a...