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steroidopenia

  1. haidut

    Oral pregnenolone as hormone replacement therapy (HRT) in humans

    As many of my readers know, the first step in steroid synthesis is the so-called "side-chain cleavage", which converts cholesterol into pregnenolone (P5). That step is known as the rate-limiting step in the steroid cascade, and its function depends on the redox status and ATP levels. In other...
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