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steroidogenesis
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F
RPF approved/peaty "PCT" protocol for testosterone base cycle?
I've decided I want to run testosterone base indefinitely for muscle building and libido purposes, but want to be careful that I have a way to recover my natural hormone production after cycle. I've run a steroid cycle before a few years back, and hoped to use SERMs to recover, as is...- feedandseed
- Thread
- bodybuilding estrogen antagonist pct pregnenolone progesterone steroid steroidogenesis testosterone
- Replies: 4
- Forum: Hormones
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Age-related steroid deficiency may be treatable with niacinamide
The study is actually about eye health, and the effects androgens play in it. However, the findings are not limited to the eyes and are in fact applicable for any other tissue/organ experiencing a decline in steroidogenesis with advancing age, which is basically all of them. As such, I am...- haidut
- Thread
- aging androgen dry eye eye hypogonadism meibomian nad niacinamide nicotinamide nicotinamide mononucleotide nicotinamide riboside nmn nr steroidogenesis
- Replies: 15
- Forum: Scientific Studies
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Next attempt to cure PFS.
Hello, I'm inquiring about a hormonal issue engendered by an 8-9 month long course of finasteride. Around 2 years after taking finasteride, I took human chloronic gonadotropin(earlier this year) which increased my male hormones, but also massively spiked my estrogen, to the point where I have...- fever257
- Thread
- 5ar finasteride hcg hormone post finasteride syndrome steroid hormones steroid production steroidogenesis
- Replies: 20
- Forum: Male Issues
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Growth hormone and thyroid hormones stimulate liver 5 alpha-reductase
https://pubmed.ncbi.nlm.nih.gov/2172247/ not sure if this study was posted- cupofcoffee
- Thread
- 5ar cortisol dht dihydrotestosterone growth hormone liver steroid steroid hormones steroidogenesis
- Replies: 2
- Forum: Thyroid and Hormones
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The skin as a steroidogenic organ
Here's a collection of studies on the skin as a steroidogenic organ mainly to show that hormones like pregnenolone have a different metabolization topically, compared to orally. "The cutaneous steroidogenic system can also have systemic effects, which are emphasized by significant skin...- Mauritio
- Thread
- androgen cholesterol lanolin lanosterol pregnenolone skin steroid steroid hormones steroidogenesis
- Replies: 275
- Forum: Cholesterol
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Low energy production (glucose metabolism) may cause andropause
As many of my readers know, aging men can also experience the equivalent of menopause and doctors informally call that state "andropause". Its official name is age-related hypogonadism and most of that hypogonadism is of the "secondary" type - i.e. the gonads appears to be in fine shape but for...- haidut
- Thread
- aging andropause energy glucose hypogonadism steroidogenesis testosterone
- Replies: 0
- Forum: Scientific Studies
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New Human Trial With An NAD Precursor
I just wanted to post this here, as it seems interest in raising NAD is high among pharma companies. While nicotinamide riboside is the most popular precursor used in the Western world, nicotinamide mononucleotide (NMN) is another one that has been used clinically. This clinical trial below...- haidut
- Thread
- aging human low dose mitochondria nad niacinamide nicotinamide mononucleotide steroidogenesis trial
- Replies: 15
- Forum: Scientific Studies
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PUFA Inhibit Progesterone Production And Thus Drive/cause Menopause
Peat wrote in a few of his articles that menopause is largely driven by a deficiency of progesterone and mentioned several anecdotes of women in their 50s and 60s getting their periods back after supplementing with large doses progesterone. In one of his articles he said that PUFA and estrogen...- haidut
- Thread
- andropause epa gonads hypogonadism inhibit menopause omega-3 progesterone pufa steroidogenesis steroids synthesis
- Replies: 7
- Forum: Scientific Studies
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H
Cholesterogenesis To Steroidogenesis: Role Of B2 In The Biosynthesis Of D
Cholesterogenesis to Steroidogenesis: Role of B2 in the Biosynthesis of D From Cholesterogenesis to Steroidogenesis: Role of Riboflavin and Flavoenzymes in the Biosynthesis of Vitamin D From Cholesterogenesis to Steroidogenesis: Role of Riboflavin and Flavoenzymes in the Biosynthesis of... -
Pregnenolone, Progesterone And DHEA Drop, Cortisol Rises In Aging
I posted a few times about the steroidal characteristics of aging. Many people think there is a drop in testosterone (T) in aging and that is what drives the frailty of aging both in men and women. However, numerous studies show that that total T does not decrease with aging. What does seem to...- haidut
- Thread
- adrenals aging cortisol dhea dht estradiol gonads pregnenolone progesterone steroidogenesis steroids testosterone
- Replies: 29
- Forum: Scientific Studies
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Effect Of Various Salt Intake On Male Rats Fertility , T , FSH , LH
Reproductive parameters and oxidative stress status of male rats fed with low and high salt diet Abstract BACKGROUND: Deficiency of minerals and micronutrients has been reported to impair the process of spermatogenesis. Historically, salt has been used by women on their husbands to increase...- paymanz
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- fertility salt steroidogenesis testosterone
- Replies: 0
- Forum: Articles & Scientific Studies
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Raising Serum Androgens Using DHEA, Pregnenolone, And Vitamin K
User testimony (4/26/2021): My Experiences With Raising Androgens Log (Pansterone, k2, magnoil) Many people use supplements like DHEA, pregnenolone, and progesterone with the goal of raising their androgens and lowering estrogen. While this approach works for raising tissue levels of steroids...- haidut
- Thread
- androgens androstenedione aromatase dhea dht gonads hypogonadism menaquinone pregnenolone serum steroidogenesis synthesis testosterone vitamin k vitamin k2
- Replies: 444
- Forum: Scientific Studies
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Nitrates / Nitrites Inhibit Androgen Synthesis By Raising NO
Ray had a separate newsletter and a radio show on the dangers of NO precursors like dietary nitrates / nitrites and supplements like arginine. It is a bit ironic that quite a few bodybuilders out there pay a lot of money for the so-called NO boosters and in reality get the exact opposite effect...- haidut
- Thread
- androgen synthesis inhibition nitrates nitric oxide nitrites steroidogenesis study
- Replies: 17
- Forum: Scientific Studies
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Testicular Steroidogenesis Decreased By Heat (Problem With Hot Baths?)
Testicular steroidogenesis is decreased by hyperthermia in old rats. - PubMed - NCBI "Hyperthermia significantly decreased the testicular testosterone level in old male rats and significantly lowered the StAR protein level. These data imply that frequent hot baths might impair testicular...- Dopamine
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- heat steroidogenesis study
- Replies: 8
- Forum: Scientific Studies
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PPI Drugs (anti GERD) Powerfully Inhibit Steroidogenesis
I have always been suspicious of PPI drugs. There are many reasons for it, including the falsified clinical trial data to conceal increased risk of gastric cancer, the idiotic premise that gastric acid increases with age, the kidney failure side effects, and the calcium/magnesium depletion being...- haidut
- Thread
- cholesterol gerd inhibition inhibitor ppi pregnenolone side cleavage side cleavage enzyme steroidogenesis steroids
- Replies: 3
- Forum: Scientific Studies
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Recovering Steroidogenesis Inhibited By Alcohol And Drugs
As many of you know, drugs like Finasteride are really bad not only because they cause a variety of CNS effects as a result of inhibiting 5-AR, but also because they systemically inhibit the entire steroid synthesis cascade. Toxins and alcohol do the same and currently there is no approved...- haidut
- Thread
- alcohol ethanol nad nad+ pregnenolone steroidogenesis testosterone
- Replies: 17
- Forum: Alcohol, Tobacco, Drugs
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Apigenin Increases Steroidogenesis
"Previous studies reported that the age-related decline in testosterone biosynthesis is associated with a decrease in the steroidogenic acute regulatory (StAR) protein which regulates the rate-limiting step of testosterone biosynthesis. To explore the possibility of delaying this decline using a...