ssri

  1. haidut

    SSRI Drugs Damage Bone By Increasing Adrenaline

    Over the last few years there have been a number of studies linking SSRI use with increased risk of fracture. Subsequent studies found this link to be definitively causal - i.e. SSRI drugs cause those fractures. However, the mechanism of action was officially ascribed to the medical...
    • haidut
    • Thread
    • adrenaline beta-blocker bone loss osteoporosis reverse serotonin ssri sympathetic
    • Replies: 9
    • Forum: Scientific Studies
  2. haidut

    Delirium In ICU Patients May Be Just Serotonin Syndrome

    I have several friends who are ER physicians and one of them works in the ICU as well. The topic of post-surgical delirium has come up many times and all of them vehemently denied that serotonin has anything to do with it. The current view is that the mechanism and cause is unknown and heredity...
    • haidut
    • Thread
    • delirium icu incompetence patients serotonin syndrome serotonin toxicity ssri
    • Replies: 5
    • Forum: Scientific Studies
  3. haidut

    The Darker Side Of Serotonin Finally Exposed - It Increases Anxiety And Suicide

    I guess the fact that such studies are finally starting to come out is a good sign. I don't think this will hurt Prozac sales in any way, but at least now doctors may start to discuss with patients the potential dangers of SSRI, which up until last year were considered to be pure myth. It still...
  4. allblues

    SSRIs And Male Fertility Markers

    Found this two-month rat study comparing 4 common SSRIs to placebo with regard to male fertility markers; The effect of sertraline, paroxetine, fluoxetine and escitalopram on testicular tissue and oxidative stress parameters in rats. - PubMed - NCBI All SSRIs adversely affected testicular...
  5. haidut

    SSRI During Pregnancy Causes Cognitive Dysfunction (autism) In Offspring

    I just posted a study that found a link between stress and elevated serotonin levels in pregnant women, which subsequently was tied to development of autism in the offspring. Stress Activates A Serotonin Gene In Pregnant Women And That Causes Autism Now, in agreement with that study a new one...
  6. haidut

    Most SSRI Ineffective In Teens, And Some Very Dangerous

    Not really surprising but at least the official evidence is piling up. Most antidepressants ineffective in teens, study finds "...Most antidepressants on the market are ineffective for children and teens with major depressive disorder, and some may be unsafe for young patients, according to...
  7. haidut

    SSRI Can Lead To Public Health Disaster

    The article's focus is UK but the same argument applies to pretty much any Western country as the SSRI are a mainstream depression drug in most of the Western world. As you can see, these drugs are often the cause for the exact same problems they are supposed to treat. What's worse, once a...
    • haidut
    • Thread
    • addictive anxiety bipolar disorder crisis public health ssri withdrawal
    • Replies: 6
    • Forum: Scientific Studies
  8. haidut

    SSRI Drugs Increase Stroke Mortality In People With Diabetes

    The study was done on people with diabetes and the presumption was that it was the diabetes that gave them the stroke, not the SSRI. I, personally, dispute that assumption and think that the SSRI was responsible for both the increased stroke incidence and increased mortality from that stroke, as...
    • haidut
    • Thread
    • clotting diabetes ischemia mortality serotonin ssri stroke
    • Replies: 3
    • Forum: Scientific Studies
  9. S

    Tianeptine Vs Escitalopram

    Influence of anxiety symptoms on improvement of neurocognitive functions in patients with major depressive disorder: A 12-week, multicenter, random... - PubMed - NCBI http://tinyurl.com/hyuogod
  10. P

    Dopaminergic Mechanism Of Antidepressant Action In Depressed Patients

    Dopaminergic mechanism of antidepressant action in depressed patients. - PubMed - NCBI Abstract Clinical studies have not yet determined a common mechanism of action for antidepressant drugs, which have primary sites of action on a variety of different neurotransmitter systems. However, a...
  11. haidut

    SSRI (Prozac) Drugs Cause Irreversible Bone Loss

    Ray has written about the detrimental effects of serotonin on bone health and how serotonin antagonist could be a potential treatment for osteoporosis. This study confirms Ray's points and shows that drug Prozac (and possible other SSRIs) causes irreversible bone loss. Selective Serotonin...
    • haidut
    • Thread
    • antagonist bone fluoxetine folate folic acid irreversible loss prozac serotonin ssri
    • Replies: 14
    • Forum: Scientific Studies
  12. J

    A Case Of Serotonin Syndrome Following Cyproheptadine Withdrawal

    A word of caution A Case of Serotonin Syndrome Following Cyproheptadine Withdrawal The user had "only" been taking 4mg twice daily for 3 weeks. (4mg is one pill, it is not a huge amount compared to what is used in many studies or to what some have used on this forum including myself).
    • jyb
    • Thread
    • case study cyproheptadine serotonin syndrome sertraline ssri
    • Replies: 6
    • Forum: Scientific Studies
  13. goodandevil

    Serotonin Uptake Inhibitors Useless For Fibromyalgia.

    AUTHORS' CONCLUSIONS: There is no unbiased evidence that SSRIs are superior to placebo in treating the key symptoms of fibromyalgia, namely pain, fatigue and sleep problems. SSRIs might be considered for treating depression in people with fibromyalgia. The black box warning for increased...
  14. haidut

    SSRI use during pregnancy doubles child autism risk

    Not really a surprise to the people on this forum, but I thought it is worth mentioning given the recent posts on maternal pregnancy stress and hypothyroidism increasing risk of autism or homosexuality. And this time the recommendation is to just "do more studies" but rather to replace SSRI...
  15. haidut

    High, Not Low, Serotonin Linked To Social Anxiety

    After decades of prescribing SSRI to treat anxiety, and especially "social" anxiety, evidence is finally being published in bastions of dogma like JAMA that anxiety disorders are likely caused by high levels of serotonin rather than low. This makes the prescription of SSRI one of the worst...
  16. haidut

    Blocking Serotonin Extends Lifespan By 40%, Triples Youthspan

    The amazing effects of blocking serotonin just keep piling on. I posted a study some time ago showing that anti-serotonin drugs like mianserin and cyproheptadine extended lifespan by 30%-40% while serotonergic drugs like SSRI shortened lifespan by as much as 80%! viewtopic.php?f=178&t=6451 Now...
    • haidut
    • Thread
    • lifespan pharmaceutical drugs serotonin ssri
    • Replies: 21
    • Forum: Articles
  17. haidut

    Antidepressants same as placebo - trials were "biased"

    This has been a long time coming. First, the official statement from one of the directors of APA saying the theory of serotonin's role in depression is backwards: viewtopic.php?f=75&t=5940 viewtopic.php?f=10&t=6298 And now, this one really drives the point home. Both on the ineffectiveness of...
  18. haidut

    Paxil - NOT safe and NOT effective

    It looks like 2015 is set become the year when big pharma finally owns up to the fiasco that its SSRI drugs are. Yet another study shows that Paxil, one of the most popular SSRI, is dangerous. Note how nobody is even suggesting that GSK somehow doctored the original research. When the recent...
  19. bluewren

    SSRI's And Youth Suicide

    More evidence of the danger of some anti depressants.... http://www.abc.net.au/news/2015-09-17/a ... ew/6783332
  20. haidut

    SSRI increase risk of violent crime

    Once again, the study apologetically tries to find an excuse for keeping SSRI in use, but the facts are unavoidable. SSRI use increases risk of violent crime. http://www.psypost.org/2015/09/study-fi ... rime-37607 "...The result was an overall association between SSRI use and violent...
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