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social defeat

  1. DDRB

    How to overcome social maladjustment (and learned helplessness)??

    I've had a lot of problems in my life, problems but the one that concerns me right now is social maladjustment. In fact the main problem is the 'cocktail effect', I see a lot of people who are even more maladjusted but who have friends because they seem basically "normal", I also have crazy...
  2. haidut

    Serotonin Causes Anhedonia. And Mental Illness In General

    As many of my readers know, anhedonia is one of the most pernicious symptoms of most mental disorders, and is perhaps the most resistant to therapy. It also happens to be one of the main triggers of attempted suicide, based on interviews with suicide survivors. I posted some threads in the past...
  3. haidut

    Energy Deficiency Due To Stress Causes Anxiety, Panic Disorders, And Subbordination

    This is a great study on so many levels. First, it directly demonstrates that chronic stress leads to mitochondrial dysfunction and reduced oxidative phosphorylation. Second, it demonstrates that glucocorticoids (cortisol) are a direct cause of this energy production downregulation. Third, it...
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