1. PopSocket

    2 years RP diet - Need your opinion - High SHBG, Low HDL, High LDL

    After almost 2 years on RP inspired diet I decided to check what is going on. I always had high SHBG and even though I switched to carbs (was on very high saturated fat diet / carnivore/keto for ~12 years and thought this is the reason) it is still 50% above upper range and barely went down/used...
  2. A.D.

    Raisin Bran for Testosterone & Libido?

    It seems like the perfect food before bed. Pros: • Wheat bran has Magnesium. • It's an Insoluble fiber which can lower estrogen. • The Raisins are good for Boron • Calcium in the Milk Here is what I'm worried about: Cons: • 80 grams of Raisin Bran has 9.5 grams of fiber. Can this raise...
  3. haidut

    SHBG may be a good test for liver (metabolic) health

    A very good study, which probably runs counter to the "mantra" most bodybuilders adhere to - i.e. they would say one must keep their SHBG low in order to increase levels of "free" steroids since, the claim goes, only free steroids are active and capable of influencing cells. If SHBG is high, the...
  4. DeadCatBounce

    What can cause 3x normal range for SHBG ?

    A friend of mine got his SHBG results sky high - 3 times the upper normal range. Normal to high T, very low free Testosterone (due to SHBG i guess) and non-existant Estrogen below the detectable limit. He has no symptoms though except being a hard gainer. He has no health issues and actually is...
  5. Cameron

    Androsterone and SHBG in training/supplementing androsterone would be of benefit in athletes

    “To determine how weight lifting training may affect serum and urinary androgens, we measured total serum testosterone (T), cortisol, sex hormone binding globulin (SHBG) and urinary testosterone, epitestosterone, androsterone, and etiocholanolone, in a group of 19 elite weight lifters after 20...
  6. P

    Effect Of Thyroid Supplementation On Testosterone And SHBG In Normal And Hypothyroid Persons

    Serum levels of total testosterone and sex hormone binding globulin in hypothyroid patients and normal subjects treated with incremental doses of L... - PubMed - NCBI Plasma testosterone (T) and sex hormone binding globulin (SHBG) were assayed in normal controls (N = 9) and hypothyroid...
  7. DaveFoster

    Progesterone Raises SHBG

    The effect of progesterone administration on sex hormone binding globulin binding capacity in women with severe premenstrual syndrome. - PubMed - NCBI Thirty-one women with severe premenstrual syndrome had low sex hormone binding globulin (SHBG) binding capacities 30.2 +/- 9.4 nmol DHT...
  8. P

    Relationship Between The Blood Concentration Of Several Metals &Endocrine Disorders Of Aging Males

    Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with m... - PubMed - NCBI Abstract Beyond 30 years of age, men experience a decline in the production of testosterone, yet only a few develop late-onset...
  9. Drareg

    Study On The Binding Of Dihydrotestosterone, Testosterone And Oestradiol With Sex Hormone Binding Gl

    These binding affinitys bring up the question of what is happening when we supplement DHT? Does it free up testosterone and estrogen,will testosterone convert to estrogen even though DHT issue oozed to suppress this? The body has probably signalled no more DHT? Nothing here breaks down the free...
  10. Drareg

    Sex Hormone-binding Globulin In Osteoporosis

    Sex hormone-binding globulin in osteoporosis. - PubMed - NCBI Abstract Sex hormone-binding globulin (SHBG) is a plasma glycoprotein that binds with high affinity to sex steroids, most notably 5alpha-dihydrotestosterone, testosterone, and 17beta-estradiol, thereby regulating their...
  11. Drareg

    Pre-diabetes And Serum Sex Steroid Hormones Among US Men

    Low circulating testosterone and SHBG yet high estraidol. SHBG has a preference to bind DHT,testosterone and lastly estraidol in that order for what I read? Abstract Several studies demonstrate a link between diabetes and sex steroid hormones, but the link with pre-diabetes remains elusive. In...
  12. Drareg

    SHBG Gene Promoter Polymorphisms In Men Are Associated With Serum Sex Hormone-binding Globulin, Andr

    This interesting in relation to the femur bone growth. SHBG gene promoter polymorphisms in men are associated with serum sex hormone-binding globulin, androgen and androgen metabolite levels, and hip bone mineral density. Abstract CONTEXT: SHBG regulates free sex steroid levels, which in...
  13. Drareg

    SHBG, Plasma, And Urinary Androgens In Weight Lifters After A Strength Training

    "Previous studies with different results have suggested that total and bioavailable testosterone levels are modified by physical exercise. Such changes may be related to modifications in cortisol levels and could be reflected in some urine androgens. To determine how weight lifting training may...
  14. haidut

    DHT Lowers Risk Of Diabetes In Older Males

    Most endocrinologists view DHT as an almost exclusively bad hormone. Aside from the its much publicized (and likely incorrect) role in prostate cancer and MPB, endocrinologists consider DHT as a causative agent in insulin resistance and even diabetes type II. Most of that misguided opinion...
  15. S

    Diet And Sex Hormone-binding Globulin

    Diet and sex hormone-binding globulin. - PubMed - NCBI
  16. D

    Excess Thyroid Increases Estrogen?

    After occasionally hearing in different threads/forums that excess thyroid can increase estrogen I looked it up and found the following studies: The interrelationships between thyroid dysfunction and hypogonadism in men and boys. Meikle AW1. Abstract .... Thyroid hormone is known to affect...
  17. N

    Progesterone Lowers SHBG

    This is a first in my research of experience of endocrine hormones. High SHBG may limit the expression of testosterone and dht. Drugs like Danazol and Winstrol can dramatically lower it, but the body usually responds by lowering T production - so a goal of increasing T by this mono therapy is...
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