sert

  1. haidut

    STUDY: high serotonin linked to dementia; MEDIA: low serotonin linked to dementia

    Once again, a level of misreporting that I am much more included to ascribe to malice than incompetence simply because most of the popular press outlets covering a specific scientific study get the study authors to proof-read the press article before publishing. So, for patently false press...
    • haidut
    • Thread
    • 5-ht alzheimer cognition dementia salt serotonin sert sodium
    • Replies: 1
    • Forum: Scientific Studies
  2. Mauritio

    Serotonin transporter gene variant linked to anxiety hostility and depression

    There is a suprsing amount of studies linking a specific variant of the serotonin transporter to higher neuroticism. Neuroticism, one of the big five traits in psychology, is defined as the proclivity to feel negative emotions like anxiety and depression. Women are higher in trait neuroticism...
  3. Mauritio

    Lack of liver steatosis in germ-free mice following hypercaloric diets, serotonin causative

    This is such an interesting study, once again underlining something RP has said for decades. Rats that have a bacteria-free gut (germ free) dont experience the same weight gain that they normally experience on a "western" a.k.a. high PUFA diet. Not only that, but feeding them high fructose...
  4. haidut

    SSRI drug use during pregnancy linked (again) to autism

    I don't think the topic needs much of an introduction. At this point, the only people who deny the causal link between SSRI use by pregnant or soon-to-become pregnant women and autism in their children are either pharma employees...or doctors who receive so much money from pharma companies to...
    • haidut
    • Thread
    • 5-ht autism autoimmunity inflammation prozac serotonin sert ssri
    • Replies: 2
    • Forum: Scientific Studies
  5. NewACC

    Platelet Serotonin Uptake Sites Increased in Drinkers of Ayahuasca

    https://pubmed.ncbi.nlm.nih.gov/7892432/ "An increased number of binding sites (Bmax) in the platelets of ayahuasca drinkers was found, while the dissociation constant (Kd) remained the same for both group."
    • NewACC
    • Thread
    • ayahuasca dmt psychedelic psychedelics serotonin serotonin antagonist serotonin transporter sert
    • Replies: 0
    • Forum: Scientific Studies
  6. haidut

    High (extracellular) serotonin causes Alzheimer's and depression

    The utter corruption of "journalism" is once again on full display in MSM. The actual scientific study is very clear in its statements/conclusions that a decrease in the levels of serotonin transporter (5-HTT) led to accumulation of beta-amyloid and onset of depression. Lower levels of 5-HTT -...
    • haidut
    • Thread
    • 5-ht 5-htt alzheimer dementia depression serotonin serotonin transporter sert
    • Replies: 22
    • Forum: Scientific Studies
  7. P

    Progesterone receptors and serotonin levels in colon epithelial cells from females with slow transit constipation (P4 lowers SERT)

    Abstract link to study Background: Females with slow transit constipation (STC) exhibit progesterone receptor (P4R) overexpression in colon muscle that impair their contractility. These studies examined whether these patients have an overexpression of P4R in epithelial cells and...
    • Peeno
    • Thread
    • 5ht constipation p4 progesterone sert
    • Replies: 3
    • Forum: Progesterone
  8. haidut

    Serotonin (and SSRI drugs) can cause anxiety and PTSD

    Yet another great study exposing just how much of a "happy hormone" serotonin really is. As usual, the popular press article does everything possible to avoid pointing the finger at serotonin and even engages in misdirection. For example, it says that SERT is the main target of drugs like...
  9. haidut

    PUFA And Serotonin Promote Each Other, And Likely Cause Mental Illness

    I neat new study that draws a direct parallel between PUFA-driven inflammation, serotonin and depression. As the study demonstrated, high levels of the PUFA arachidonic acid (AA) are highly correlated with lower density (expression) of the serotonin transported (SERT, 5-HTT), and the...
    • haidut
    • Thread
    • 5-ht 5-htt bipolar depression inflammation mental illness pufa serotonin serotonin transporter sert suicide
    • Replies: 4
    • Forum: Scientific Studies
  10. haidut

    Serotonin Excess, Not Dopamine Deficiency, May Be The Cause Of Parkinson

    One of the most paradigm-challenging studies I have seen this year and, unsurprisingly, mainstream media is pulling all sorts of tricks to avoid naming the culprit directly. Even the press release and the study abstract are worded in a convoluted way, talking about a "serotonin dysfunction"...
    • haidut
    • Thread
    • advance cause decade excess iatrogenic parkinson predict serotonin sert shaking ssri tremor
    • Replies: 26
    • Forum: Scientific Studies
  11. haidut

    Elevated Serotonin Increases Criminal Activity

    The study looked at correlations between ambient temperature and criminal activity and found that higher temperatures correlate with reduced SERT density and as such elevated serotonin. The SERT protein is the one that deactivates serotonin and it is a sodium dependent protein. Serotonin...
    • haidut
    • Thread
    • cause crime criminal activity criminal behavior drive promote psychosis serotonin sert violence
    • Replies: 58
    • Forum: Scientific Studies
  12. L

    Androgens Increases SERT, Estrogens Decreases It

    SERT aka serotonin reuptake transporter reduces serotonin levels. This study show that testosterone increases SERT levels whiles estradiol & anti-androgen decreases it. High-Dose Testosterone Treatment Increases Serotonin Transporter Binding in Transgender People. - PubMed - NCBI ...SERT...
  13. haidut

    Serotonin/endotoxin/PUFA As Primary Causes Of Depression And Diabetes; Can Be Easily Blocked

    This is one of the unique studies that breaks away from the mainstream dogma that serotonin is the "happy hormone" and increasing it with drugs like SSRI can lead to nothing but goodness. The study not only directly states that past/current SSRI use is a risk for developing diabetes but show how...
    • haidut
    • Thread
    • 5-ht 5-ht3 5-htt diabetes endotoxemia endotoxin inflammation liver disease lps obesity pufa serotonin serotonin transporter sert tlr4
    • Replies: 45
    • Forum: Scientific Studies
  14. haidut

    Tremor In Parkinson Disease (PD) Is Due To High Serotonin

    The non-motor signs/symptoms of PD (tremor, drooling, slurred speech, etc) have long been thought to be directly due to dopamine deficiency due to the death of the nigrostriatal dopamine neurons. The common treatment for those signs/symptoms and the motor symptoms as well is usually a dopamine...
    • haidut
    • Thread
    • excess parkinson pd serotonin serotonin transporter sert ssri tremor
    • Replies: 20
    • Forum: Scientific Studies
  15. haidut

    Colon Aging / Cancer? Due To Low NAD / High Serotonin; Niacinamide Reverses Both

    Peat has said many times that the impaired bowel regularity that occurs in aging, hypothyroidism and various pathologies is due to high NO and serotonin. He also said that while serotonin inhibits motility in the colon it increases it in the small intestine. Most doctors do not agree with that...
    • haidut
    • Thread
    • 5-ht4 aging colon colon cancer niacinamide nmn serotonin serotonin uptake sert tph tph2
    • Replies: 33
    • Forum: Scientific Studies
  16. allblues

    Serotonin Transporter Deficiency Drives Estrogen-dependent Obesity And Glucose Intolerance

    This 2017 study here is making me scratch my head. Serotonin transporter deficiency drives estrogen-dependent obesity and glucose intolerance So these people genetically deleted the serotonin transporter in a group of mice, and pharmacologically antagonized it with an SSRI in another group of...
  17. haidut

    Higher Serotonin Availability May Be The Cause Of Cognitive Impairment / Dementia

    Some of you may have seen this study in the news lately. However, it is being presented as the exact opposite as what my title says. The media titles all over the Internet proclaim that "John Hopkins study shows low serotonin causes dementia". However, if you look at the actual study you will...
    • haidut
    • Thread
    • alzheimer's cause cognitive impairment dementia serotonin serotonin transporter sert ssri
    • Replies: 8
    • Forum: Scientific Studies
  18. haidut

    Poverty Causes Depression By Increasing Serotonin Activity

    The conditions of learned helplessness and PTSD have many features in common and both of them have been linked to dysfunction of the monoaminergic system. There has been a lot of research over the last decade tying adverse life conditions in childhood to mood and memory problems as an adult...
    • haidut
    • Thread
    • depression methylation poverty serotonin sert slc6a4 stress
    • Replies: 53
    • Forum: Scientific Studies
  19. haidut

    Zinc Acts Similar To Tianeptine And Blocks SSRI Drug Effects

    Basically, the study says that zinc increases serotonin uptake, making it a "SERT" drug acting in a manner opposite to SSRI drugs. The study even compared zinc effects to some well-known SSRI drugs. I thought that was pretty cool, and a possible alternative for people with no access to...
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