serotonin

  1. tonto

    Is Serotonin An Upper Or A Downer?

    (my first post, love the site!) I found this article* a few months ago and thought others on this site would like it if it hasn't been shared before. Some highlight for me was the section on "the serotonin system and energy regulation", and the understanding by the authors that serotonin is...
  2. P

    Ondansetron Works For Diarrhea-Predominant Irritable Bowel Syndrome

    Ondansetron Works for Diarrhea-Predominant Irritable Bowel Syndrome - NEJM Journal Watch This 5-HT3 receptor antagonist improved stool consistency and symptoms, with a low frequency of severe constipation. Ondansetron is a 5-hydroxytryptamine 3 receptor antagonist (5-HT3RA) used for the...
  3. haidut

    Schizophrenia / Psychosis Linked To Traumatic Experience And Stress

    I have suspected this for a long time, but the official version to this day is that schizophrenia is primarily a gene-driven disease linked to a "misbehaving" cluster of about 300 genes. The fact that most of these genes are related to serotonin metabolism is considered, of course, irrelevant to...
    • haidut
    • Thread
    • epigenetics life experience psychosis schizophrenia serotonin stress trauma
    • Replies: 7
    • Forum: Scientific Studies
  4. Koveras

    Serotonin Can Be Metabolized To Nitric Oxide

    May explain one of the mechanisms of serotonin's inflammatory effect in the brain, gut, and elsewhere. 5-Hydroxytryptamine is biotransformed by CYP2C9, 2C19 and 2B6 to hydroxylamine, which is converted into nitric oxide. "There is circumstantial evidence suggesting that 5-hydroxytryptamine...
  5. haidut

    Anti-serotonin, Pro-dopamine Drug Approved For Psychosis And Bipolar Disease

    After more than 5 decades of claiming that psychosis conditions like schizophrenia are caused by excessive dopaminergic activity and depression is a deficiency of serotonin, big pharma is doing 180 degrees reversal. A new drug was just approved for treating bipolar disorder and schizophrenia in...
    • haidut
    • Thread
    • agonist antagonist bipolar disorder disease dopamine psychosis schizophrenia serotonin
    • Replies: 22
    • Forum: Scientific Studies
  6. haidut

    Cyproheptadine May Prevent And Treat HIV Infection

    A few months ago I posted a study showing cyproheptadine being potentially effective against Ebola and rabies viruses. Cyproheptadine may treat Ebola infection In another study, it was shown that the serotonin receptor is vital for infection and replication with viruses like JCV. The JCV uses...
  7. haidut

    Dmso Is Similar To Reserpine, Lowers Serotonin, Increases MAO-A

    I have suspected that DMSO has central effects given how powerfully sedating it can be for some people. This older study compares the effects of DMSO to the ancient tranquilizer reserpine, which Peat has written about before. This would make DMSO an effective serotonin lowering agent, an...
    • haidut
    • Thread
    • depression dmso mao-a methylene blue psychosis reserpine serotonin
    • Replies: 45
    • Forum: Scientific Studies
  8. haidut

    Amazing Medicinal Properties Of Beta-lapachone (β-lapachone)

    This thread is similar to the one I created for emodin and in support of the Lapodin supplement I released. Lapodin: Lapodin - Dietary Supplement With Beta-lapachone And Emodin | Ray Peat Forum Emodin: Amazing Medicinal Properties Of Emodin | Ray Peat Forum The purpose of this thread is to...
    • haidut
    • Thread
    • antibacterial antifungal antiviral beta-lapachone cancer cortisol cvd depression diabetes endotoxin estrogen inflammation lapachone nad napththoquinone neurological nitric oxide obesity serotonin β-lapachone
    • Replies: 22
    • Forum: Supplements
  9. haidut

    Amazing Medicinal Properties Of Emodin

    This thread is similar to the one I created for beta-lapachone and in support of the Lapodin supplement I released. Lapodin: https://raypeatforum.com/community/threads/lapodin-dietary-supplement-with-beta-lapachone-and-emodin.9423/ Beta-lapachone...
    • haidut
    • Thread
    • antibacterial antifungal antiviral cancer cortisol diabetes digestion emodin endotoxin estrogen inflammation nad neurological nitric oxide obesity scientific serotonin stress supplemental tnf
    • Replies: 44
    • Forum: Cascara Sagrada
  10. goodandevil

    Serotonin Uptake Inhibitors Useless For Fibromyalgia.

    AUTHORS' CONCLUSIONS: There is no unbiased evidence that SSRIs are superior to placebo in treating the key symptoms of fibromyalgia, namely pain, fatigue and sleep problems. SSRIs might be considered for treating depression in people with fibromyalgia. The black box warning for increased...
  11. michael94

    Lsd: Antagonizes Serotonin And Glutamate Excitation

    http://www.ncbi.nlm.nih.gov/pubmed/5492893
  12. C

    Help Me With My Dissertation On Serotonin Guys?

    Hello guys, been a while since ive been here, but ive been kinda busy with my education. Im doing a degree in herbal medicine, and am in my third year, which means dissertation. Ive been trying (and failing) to convince everyone on my course that serotonin is not really something you want to...
  13. michael94

    Serotonin Production In Adipose Tissue A Possible Target Of Obesity Drugs In The Future

    https://l.facebook.com/l.php?u=http%3A%2F%2Fwww.molcells.org%2Fjournal%2Fdownload_pdf.php%3Fdoi%3D10.14348%252Fmolcells.2015.0258&h=LAQEE-Yae ( will download full text as pdf )
  14. haidut

    High, Not Low, Serotonin Linked To Social Anxiety

    After decades of prescribing SSRI to treat anxiety, and especially "social" anxiety, evidence is finally being published in bastions of dogma like JAMA that anxiety disorders are likely caused by high levels of serotonin rather than low. This makes the prescription of SSRI one of the worst...
  15. haidut

    Blocking Serotonin Extends Lifespan By 40%, Triples Youthspan

    The amazing effects of blocking serotonin just keep piling on. I posted a study some time ago showing that anti-serotonin drugs like mianserin and cyproheptadine extended lifespan by 30%-40% while serotonergic drugs like SSRI shortened lifespan by as much as 80%! viewtopic.php?f=178&t=6451 Now...
    • haidut
    • Thread
    • lifespan pharmaceutical drugs serotonin ssri
    • Replies: 21
    • Forum: Articles
  16. S

    Dysregulated Dopamine Release From Serotonin Terminals Is The Prime Trigger Of Dyskinesia In The Rat

    Dopamine released from 5-HT terminals is the cause of l-DOPA-induced dyskinesia in parkinsonian rats
  17. S

    BDNF Decreases Extracellular Levels of Serotonin

    Influence of brain-derived neurotrophic factor (BDNF) on serotonin neurotransmission in the hippocampus of adult rodents.
  18. NathanK

    Shutting off serotonin turns lab rat study into an orgy

    This is an older 1970 study that I'm sure Ray has seen. I posted on the RPI FB group a week or two ago and thought I'd share: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1702805/ Researchers permanently shut down serotonin in adult male rats. Subsequent libido and "mounting" activity went...
  19. milk_lover

    According To A Study Done In 1988, Caffeine Can Increase Brain Serotonin Levels

    http://nutritionreviews.oxfordjournals. ... /46/10/366 I don't have an access to the full study. The abstract says the following: "High [d?]closes of caffeine produced increases in tryptophan and serotonin in brains of rats." Has anybody read the full study, checked if it was soundly designed...
    • milk_lover
    • Thread
    • brain caffeine serotonin supplemental
    • Replies: 11
    • Forum: Articles
  20. murdoc

    Limonene Reduces Serotonin During Stress

    Hi! This is my first post, but I have been following this forum for some months now. I came from Germany so English is not my mother tongue. I just wanted to share my findings about Limonene and its anti-stress properties. I was interested in essential oils due to their antimicrobial...
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