serotonin

  1. haidut

    Serotonin/endotoxin/PUFA As Primary Causes Of Depression And Diabetes; Can Be Easily Blocked

    This is one of the unique studies that breaks away from the mainstream dogma that serotonin is the "happy hormone" and increasing it with drugs like SSRI can lead to nothing but goodness. The study not only directly states that past/current SSRI use is a risk for developing diabetes but show how...
    • haidut
    • Thread
    • 5-ht 5-ht3 5-htt diabetes endotoxemia endotoxin inflammation liver disease lps obesity pufa serotonin serotonin transporter sert tlr4
    • Replies: 45
    • Forum: Scientific Studies
  2. haidut

    Tremor In Parkinson Disease (PD) Is Due To High Serotonin

    The non-motor signs/symptoms of PD (tremor, drooling, slurred speech, etc) have long been thought to be directly due to dopamine deficiency due to the death of the nigrostriatal dopamine neurons. The common treatment for those signs/symptoms and the motor symptoms as well is usually a dopamine...
    • haidut
    • Thread
    • excess parkinson pd serotonin serotonin transporter sert ssri tremor
    • Replies: 20
    • Forum: Scientific Studies
  3. haidut

    Serotonin / PUFA Drive Migraine

    The role of serotonin in migraines is becoming more recognized every day. Unfortunately, SSRI drugs are still being used to treat migraines, but more recent studies found that serotonin antagonists like cyproheptadine or mianserin are much more effective. The study below found that linoleic...
    • haidut
    • Thread
    • aspirin cyproheptadine inflammation migraines prostaglandins pufa serotonin sfa
    • Replies: 14
    • Forum: Scientific Studies
  4. haidut

    Cardenosine - Liquid Product For R&D

    Our new product is finally here and it is "all about the ATP". I mentioned quite a few times on the forum and over email that we plan on releasing an ATP product and people have been asking me about it for the last few months. It seems a very simple task at first but we thought that we can do a...
    • haidut
    • Thread
    • aging atp cancer cardenosine cortisol dopamine infection inflammation inosine ketoproline metabolism oxoproline p5p pyridoxal-5-phosphate pyroglutamate pyroglutamic acid serotonin succinate succinic acid vitamin b6
    • Replies: 408
    • Forum: IdeaLabs
  5. haidut

    Colon Aging / Cancer? Due To Low NAD / High Serotonin; Niacinamide Reverses Both

    Peat has said many times that the impaired bowel regularity that occurs in aging, hypothyroidism and various pathologies is due to high NO and serotonin. He also said that while serotonin inhibits motility in the colon it increases it in the small intestine. Most doctors do not agree with that...
    • haidut
    • Thread
    • 5-ht4 aging colon colon cancer niacinamide nmn serotonin serotonin uptake sert tph tph2
    • Replies: 33
    • Forum: Scientific Studies
  6. haidut

    Serotonin Is The Likely Cause Of Septic And Anaphylactic Shock

    I am hoping that as a result of this study, mainstream medicine will finally start to take the pathogenic role of peripheral serotonin more seriously. More importantly, this study points to a rather simple and safe way of treating two of deadliest acute reactions (sepsis and allergic shock)...
    • haidut
    • Thread
    • 5-ht anaphylaxis bacteria infection platelets sepsis serotonin shock virus
    • Replies: 7
    • Forum: Scientific Studies
  7. haidut

    Inosine As A Powerful Inhibitor Of Serotonin And Cortisol Synthesis

    As many of you know, I have been reading older Russian studies on many of the substances Peat talks about. He mentioned inosine in one of is articles, but only in relation to improving immunity and preventing dementia. The problem of Alzheimer's disease as a clue to immortality Part 1...
    • haidut
    • Thread
    • hypoxanthine inhibitor inosine mao-a mao-b serotonin synthesis
    • Replies: 40
    • Forum: Scientific Studies
  8. haidut

    Vitamin K (and Other Naphthoquines) Are Pro-dopamine And Anti-serotonin

    This is a pair of studies, which shows that 1,4-naphthoquinones stimulate serotonin uptake in platelets in a manner similar to other SSRE such as tianeptine and in opposition to SSRI drugs like Prozac (fluoxetine). The stimulation of serotonin uptake by vitamin K3 (menadione) and other similar...
    • haidut
    • Thread
    • dopamine mao-b menadione naphthoquinone rasagiline selegiline serotonin serotonin uptake vitamin k vitamin k3
    • Replies: 13
    • Forum: Scientific Studies
  9. haidut

    Chronic Fatigue Syndrome (ME/CFS) May Be Caused By Increased Serotonin Sensitivity

    Despite the denials of mainstream medicine that CFS exists as an organic disorder, many studies have been done on the etiology of the fatigue and how it often follows an acute illness, usually of "viral" origin. Due to the fact that the role of serotonin in inducing fatigue is well-known...
    • haidut
    • Thread
    • 5-ht2a cfe chronic fatigue syndrome depression expression increased inflammation myalgic encephalopathy receptors serotonin
    • Replies: 95
    • Forum: Scientific Studies
  10. haidut

    SSRI Drugs (Prozac) Worsen Prenatal Stress And May Contribute To Autism

    I am posting this study because it may explain why the incidence of autism is much higher in male than in female offspring. As I posted in a few other threads before, serotonin is one of the likely direct causes of the autism pathology and it is of course elevated during chronic stress...
    • haidut
    • Thread
    • autism endotoxin exacerbate fluoxetine lps prenatal prozac serotonin ssri stress tlr4 worsen
    • Replies: 3
    • Forum: Scientific Studies
  11. haidut

    Paternal Use Of SSRI Increase Risk For ADHD In His Children

    By now even the general public has gotten a wind of just how bad the SSRI drugs are. But most of the studies demonstrating negative effects from SSRI use are focused on the health of the patient taking them or the health of the baby whose mother is taking SSRI while pregnant or during...
    • haidut
    • Thread
    • adhd children father increase offspring paternal risk serotonin ssri use
    • Replies: 4
    • Forum: Scientific Studies
  12. Koveras

    Vitamin A May Be A Viable Therapy For Autism (human Study)

    Haidut has made several posts previously on autism, including on the potential therapeutic role of vitamin D and the potential causative role of serotonin. Vitamin D May Be A Viable Therapy For Autism (human Study) Children Conceived In Winter Have Much Higher Risk Of Autism Gut Dysbiosis May...
  13. haidut

    SSRI Drugs May Cause Serious Lung Disease And Fibrosis

    The study tries to downplay the risk by claiming that it is only relevant to "old, frail people". However, the specific lung issue linked to SSRI - bronchiectasis - is almost never found as an independent disease but rather almost always as a symptoms of cystic fibrosis. Given serotonin's...
    • haidut
    • Thread
    • 5-ht2b bronchiectasis cystic fibrosis lung damage lung disease serotonin snri ssri
    • Replies: 14
    • Forum: Scientific Studies
  14. haidut

    Bonobos Are Altruistic (without Payback And Without Encouragement)

    I have posted before studies in regards to the link between metabolism, energy and highly valued human qualities like altruism, and helpfulness. As has been confirmed in humans, egalitarian beliefs, altruism and generally friendly behavior towards complete (genetic) strangers requires good...
    • haidut
    • Thread
    • altruism bonobo encouragement energy metabolism payback serotonin thyroid unselfish
    • Replies: 75
    • Forum: Scientific Studies
  15. haidut

    SSRI Make Organisms Demented, Violent & Homicidal, Even At Low Doses

    I posted a few studies on the now proven causal link between SSRI use and violent, psychotic behavior. SSRI increase risk of violent crime This new study found that the profoundly negative effect of SSRI on behavior is evident even in crabs, and even when they were exposed to very low...
    • haidut
    • Thread
    • aggressive behavior dementia fluoxetine homicide prozac serotonin ssri violence
    • Replies: 39
    • Forum: Scientific Studies
  16. haidut

    Serotonin Causes Liver Cancer And Metastases In Colon Cancer

    The role of serotonin in fibrosis is well-known despite the public lies thrown around by Big Pharma. I opsted about the behind-the-scenes acquisition of the serotonin antagonist terguride, which Pfizer is now hoping to be able to treat ANY fibrotic condition (as shown by a recently filed FDA...
    • haidut
    • Thread
    • 5-ht cause colon cancer fibrosis liver cancer metastases serotonin
    • Replies: 13
    • Forum: Scientific Studies
  17. haidut

    SSRI Use In Children Dramatically Increases Risk Of Diabetes In Adulthood

    The bad news for SSRI just keep on piling. Given serotonin's role as a master metabolic inhibitor this findings is not really surprising. There are a number of clinical trials underway with serotonin synthesis (TPH) inhibitors as treatment of obesity, insulin resistance and diabetes II. As of...
    • haidut
    • Thread
    • adulthood children chronic use diabetes high dose increase long-term use risk serotonin ssri
    • Replies: 3
    • Forum: Scientific Studies
  18. P

    Low Carb Diet,FFAs, High Free Tryptophan, Serotonin ,fatigue

    Also the question of "does a high fat meal increase free fatty acid levels?" The answer is yes!it does. Low-Carbohydrate-High-Fat Diet: Can it Help Exercise Performance? Low-carbohydrate-high-fat (LCHF) diets have been used as a means of weight loss and control of symptoms in several...
  19. P

    High Carb Meal If Not Accompanied By Protein , Can Increase Serotonin

    Of curse it is after a fasting state. Carbohydrate ingestion and brain serotonin synthesis: relevance to a putative control loop for regulating carbohydrate ingestion, and effects of as... - PubMed - NCBI The ingestion of a meal of carbohydrates by fasting rats rapidly increases brain...
  20. haidut

    Cocaine "addiction" May Be Driven By Serotonin

    Another study on addiction and its mechanisms, but this one focuses on cocaine which is the second most highly abused drug after alcohol, at least in the US (excluding weed). This new study shows that blocking the serotonin receptor 7 (5-HT7) blocked the cocaine abuse behavior. This would...
    • haidut
    • Thread
    • 5-ht7 abuse addiction antibiotics charcoal cocaine cyproheptadine metergoline serotonin
    • Replies: 2
    • Forum: Scientific Studies
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