sarcopenia

  1. haidut

    HUMAN STUDY: Vitamin B3 ups muscle/bone mass/strength, lowers fat, improves glucose control

    The study is epidemiological and it did not distinguish between the various forms of vitamin B3 available through the diet or supplements. However, it was well-controlled and its findings match the known biochemical effects of vitamin B3, which the study authors cite themselves as the likely...
    • haidut
    • Thread
    • diabetes fat insulin muscle niacin niacinamide nicotinamide sarcopenia vitamin b3
    • Replies: 13
    • Forum: Scientific Studies
  2. cs3000

    Hesperidin in 1 glass of orange juice reverses sarcopenia, lowers inflammation, & restores IGF-1 (age related muscle loss)

    Cool research as OJ is commonly accessible, nice effect on restoring igf-1 lowering inflammation and reversing muscle loss in aging (and probably myelin repair for brain function too), and its effect is in already aged mice so can be taken later in life for this health boost 1 250ml glass of...
    • cs3000
    • Thread
    • age related muscle aging atrophy igf-1 m1 macrophage muscle loss myelin orange juice sarcopenia
    • Replies: 13
    • Forum: Scientific Studies
  3. Limon9

    MTOR Increases With Aging/Sarcopenia, (Partial) Inhibition Restores Muscle Mass

    This was a nice experiment which upsets the naive axis of anabolism and catabolism commonly-associated with the mTOR (mammalian target of rapamycin). Its activation is not sufficient to maintain muscle mass, and partially inhibiting it can unexpectedly restore muscle. Common medical advice is...
  4. haidut

    Muscles starve/waste in the absence of vitamin D

    As turns out, yet again, vitamin D is far from being the simple "bone vitamin" as most TV/online commercials would have us believe. It is actually a (seco)steroid and has already been implicated in a host of metabolic and immune process affecting virtually every disease. Recently, I posted a few...
    • haidut
    • Thread
    • cholecalciferol energy glucose glycogen muscle sarcopenia vitamin d wasting
    • Replies: 3
    • Forum: Scientific Studies
  5. haidut

    Muscle weakness / wasting linked to poor mitochondrial function

    A study that once again illustrates the central principle of bioenergetics - structure and function cannot be separated. They are interdependent at every level. In this specific case, the "structural" pathology is muscle weakness and wasting (sarcopenia, cachexia, etc). Most doctors, when...
    • haidut
    • Thread
    • atp atrophy cachexia metabolism mitochondria muscle weakness oxphos sarcopenia
    • Replies: 4
    • Forum: Scientific Studies
  6. haidut

    Vitamin D deficiency impairs muscles by lowering energy production

    Perhaps this study below will put some of the arguments against vitamin D supplementation to rest. It demonstrated up to 40% reduction of energy production in the muscles of animals deficient in vitamin D, in spite of unchanged number/size/density of mitochondria inside the cells. In addition...
    • haidut
    • Thread
    • cholecalciferol energy mitochondria muscle oxphos sarcopenia vitamin d vitamin d3
    • Replies: 2
    • Forum: Scientific Studies
  7. haidut

    DHT restores anabolism / vitality / sexuality even in 90+ y.o. males

    A great study, a true blast from the (better) past, when androgenic steroids and especially DHT were not considered the devil reincarnate, but were commonly used for all types of ailments, including the broad physiological and psychological symptoms of aging such as sarcopenia (muscle loss)...
    • haidut
    • Thread
    • anabolism androgen dht euphoria libido osteoporosis sarcopenia sexuality stanolone vitality
    • Replies: 42
    • Forum: Scientific Studies
  8. haidut

    Intermittent Fasting (IF) Ineffective And May Even Be Dangerous

    I have no doubt the findings of this study will quickly get dismissed by the massive industry that has formed around the idea that ANY weight loss is a good thing, and, just as importantly, if you lose weight while torturing yourself (in this with fasting) somehow the "gains" are even more...
    • haidut
    • Thread
    • dangerous diet fasting ineffective intermittent fasting muscle loss sarcopenia
    • Replies: 7
    • Forum: Scientific Studies
  9. haidut

    Cholesterol And SFA Are Anabolic; PUFA/MUFA Akin To Chemical Castration

    A pair of interesting study and a commentary in the highly respected Journals of Gerontology. Namely, higher cholesterol intake is associated with much higher lean muscle mass accrual as a result of weight lifting. Interestingly, higher protein intake was not. Even more interestingly, and much...
    • haidut
    • Thread
    • anabolic androgens anticatabolic castration cholesterol eggs mufa muscle pufa sarcopenia saturated fat sfa
    • Replies: 28
    • Forum: Scientific Studies
  10. haidut

    Glycine Is Directly Anabolic AND Anticatabolic For The Muscle

    I posted a few interesting studies about glycine in the past. Among the interesting properties are lowering cortisol, increasing DHT synthesis, improving insulin sensitivity, and serving as a biomarker of stress. Glycine Powerfully Lowers Cortisol Glycine Strongly Upregulates 5-alpha Reductase...
    • haidut
    • Thread
    • anabolic anti-catabolic glycine inflammation mtor muscle protein synthesis sarcopenia
    • Replies: 64
    • Forum: Scientific Studies
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