sarcopenia

  1. haidut

    Muscle weakness / wasting linked to poor mitochondrial function

    A study that once again illustrates the central principle of bioenergetics - structure and function cannot be separated. They are interdependent at every level. In this specific case, the "structural" pathology is muscle weakness and wasting (sarcopenia, cachexia, etc). Most doctors, when...
  2. haidut

    Vitamin D deficiency impairs muscles by lowering energy production

    Perhaps this study below will put some of the arguments against vitamin D supplementation to rest. It demonstrated up to 40% reduction of energy production in the muscles of animals deficient in vitamin D, in spite of unchanged number/size/density of mitochondria inside the cells. In addition...
  3. haidut

    DHT restores anabolism / vitality / sexuality even in 90+ y.o. males

    A great study, a true blast from the (better) past, when androgenic steroids and especially DHT were not considered the devil reincarnate, but were commonly used for all types of ailments, including the broad physiological and psychological symptoms of aging such as sarcopenia (muscle loss)...
  4. haidut

    Intermittent Fasting (IF) Ineffective And May Even Be Dangerous

    I have no doubt the findings of this study will quickly get dismissed by the massive industry that has formed around the idea that ANY weight loss is a good thing, and, just as importantly, if you lose weight while torturing yourself (in this with fasting) somehow the "gains" are even more...
  5. haidut

    Cholesterol And SFA Are Anabolic; PUFA/MUFA Akin To Chemical Castration

    A pair of interesting study and a commentary in the highly respected Journals of Gerontology. Namely, higher cholesterol intake is associated with much higher lean muscle mass accrual as a result of weight lifting. Interestingly, higher protein intake was not. Even more interestingly, and much...
  6. haidut

    Glycine Is Directly Anabolic AND Anticatabolic For The Muscle

    I posted a few interesting studies about glycine in the past. Among the interesting properties are lowering cortisol, increasing DHT synthesis, improving insulin sensitivity, and serving as a biomarker of stress. Glycine Powerfully Lowers Cortisol Glycine Strongly Upregulates 5-alpha Reductase...
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