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redox

  1. haidut

    "Reductive" stress harms cells, mitochondria protect by increasing metabolism

    Finally a study that provide me with some "ammo" during my arguments with people I know who work in the medical profession. A common topic in such arguments is the mainstream medical idea that it is almost impossible to have too much antioxidants and too little oxidation. In fact, to many...
    • haidut
    • Thread
    • metabolism mitochondria oxidation redox reduction stress sulfhydryl thiol
    • Replies: 23
    • Forum: Scientific Studies
  2. haidut

    Niacinamide + pyruvate may treat glaucoma (human study)

    Some excellent results from a human clinical trial. Namely, a combination of 3g niacinamide and 3g (calcium) pyruvate daily demonstrated significant therapeutic effect in patients with already established glaucoma. I can't access to actual study link on JAMA, but I suspect the mechanism of...
    • haidut
    • Thread
    • energy glaucoma niacinamide pyrucet pyruvate redox vitamin b3
    • Replies: 10
    • Forum: Scientific Studies
  3. Hans

    An optimal metabolism: a look at the furnace within

    What should a true metabolism look like? What should we even look at? I dived a bit deep on this one and hopefully it provides answers for some. I'm discussing redox couples, such as NAD/NADH, GSH/GSSG and cysteine/cystine and how they affect energy production, ROS, hormone and neurotransmitter...
  4. haidut

    Low, Not High, Metabolism Creates Oxidative Stress

    A hugely popular tenet of the "rate of living" theory is that the higher the metabolic rate the more reactive oxygen species (ROS) an organism produces. ROS elevation has already been implicated in a host of chronic disease including diabetes, CVD, cancer, neurological conditions and even mental...
    • haidut
    • Thread
    • electron acceptor metabolism oxidation oxidative stress oxphos redox reduction ros
    • Replies: 6
    • Forum: Scientific Studies
  5. haidut

    Alcohol Causes Liver (and Other Organ) Damage By Lowering NAD/NADH Ratio

    A neat little study, which demonstrates once again the crucial role of energy and optimal redox status in a public health issue that has now reached catastrophic proportions. Namely, alcohol-related morbidity and mortality. Those have always been an issue in any developed country but since the...
  6. haidut

    Vitamin K May Treat Leukemia

    Another great study demonstrating both the therapeutic potential of vitamins as well as the metabolic/redox nature of cancer. As I mentioned in some of my podcasts, vitamin K2 (MK-4) is currently in clinical trials for treating/preventing a number of different cancers, especially liver cancer...
    • haidut
    • Thread
    • leukemia menaquinone mk-4 redox ros stem cells treat vitamin c vitamin k vitamin k2 vitamin k3
    • Replies: 2
    • Forum: Scientific Studies
  7. haidut

    Pyrucet - Liquid (ethyl) Pyruvate/Aceatoacetate Mix

    As many forum users know, I have been interested in the Randle Cycle (glucose/fat competition for oxidation) for quite some time. The topic of limiting fatty acid oxidation (FAO) and promoting glucose oxidation is pretty central to the metabolic theory of health. Peat has written many times on...
    • haidut
    • Thread
    • acetoacetate brain dementia endotoxin ethyl acetoacetate ethyl pyruvate fao fatty acid oxidation glucose oxidation gssg heart attack idealabs metabolism nad/nadh oxidation pdh pyruvate redox sepsis stroke
    • Replies: 553
    • Forum: IdeaLabs
  8. haidut

    High-dose Vitamin C Is Making A Comeback As A Treatment For Cancer

    It look like Linus Pauling may have the last laugh after all. The studies below show that high-dose IV therapy with vitamin C dramatically increases survival of several highly lethal cancers (e.g. pancreatic). Even the lead author is in disbelief and says the results are unheard of...
    • haidut
    • Thread
    • advanced ascorbic ascorbic acid cancer dehydroascorbic high-dose lung menadione methylene blue neuroblastoma ovarian oxidized pancreatic quinone redox ros treatment vitamin c vitamin k
    • Replies: 63
    • Forum: Scientific Studies
  9. haidut

    High Metabolism And/Or Progesterone Can Regrow Amputated Limbs

    Another great example of "synchronicity" (Synchronicity - Wikipedia) happened today. Two separate but related studies, with similar organisms, popped up today in my mailbox. One of them (at UCDavis) shows that the redox status in favor of oxidation, and thus high reactive oxygen species (ROS)...
    • haidut
    • Thread
    • amputated amputation dhea hydrogen peroxide limbs metabolism oxidation progesterone redox regeneration regrow ros uncoupling
    • Replies: 54
    • Forum: Scientific Studies
  10. haidut

    Low Dose DHEA Powerfully Shifts The Redox Status Towards Oxidation

    A great study, which shows that low-dose DHEA in the range discussed here on the forum (about 15mg daily) not only completely reversed the reductive stress seen in very old mammals but put the aging animals in an even more oxidized state than their very young counterparts. This study matches...
    • haidut
    • Thread
    • aging cancer dhea g6pd g6pdh gsh gssg oxidation redox shift
    • Replies: 22
    • Forum: Scientific Studies
  11. haidut

    Niacinamide Can Treat Alcoholic Liver Disease

    As many forum users have probably heard on the news, alcohol abuse is now a leading cause of death in young people under 35. It is projected to soon surpass drug overdose as a cause of death in this demographic. Millennials are dying of alcohol-related liver disease at increasing rates The...
    • haidut
    • Thread
    • alcohol alcoholism cirrhosis liver liver disease liver steatosis nad nad/nadh niacinamide nicotinamide riboside nr prevent redox
    • Replies: 3
    • Forum: Scientific Studies
  12. haidut

    The Warburg "effect" Is, In Fact, A Direct Cause Of Cancer

    This is yet another recent study showing that medicine may finally be getting on the right track. Similar to the human study with doxycycline and breast cancer I just posted, confirms again what has been known and fraudulently suppressed for almost a century. Namely, the Warburg "effect" is as...
    • haidut
    • Thread
    • cancer cause development initiation lactate lactic acid oxidation progression redox reduction tumor warburg effect
    • Replies: 165
    • Forum: Scientific Studies
  13. haidut

    Methylene Blue (MB) May Allow Creating Near-perfect (redox) Batteries

    Interesting study on using the redox properties of MB as a way to store electrons and then extract them as needed - i.e. the primary mechanism behind any modern battery. https://onlinelibrary.wiley.com/doi/abs/10.1002/celc.201801097 This bright blue dye is found in fabric: Could it also power...
    • haidut
    • Thread
    • batteries efficiency electricity electrons flow mb methylene blue properties redox
    • Replies: 9
    • Forum: Scientific Studies
  14. haidut

    Niacinamide May Treat (acute) Kidney Failure (AKI) - Human Study

    It seems modern medicine is slowly starting to recognize the role of energy in organ health, and more specifically the role of NAD/NADH ratio in variety of diseases long thought to be mostly mechanism in origin. A few months ago, I posted a study on raising NAD levels with nicotinamide riboside...
    • haidut
    • Thread
    • acute kidney injury aki creatinine kidney disease kidney failure nad nad+ nad/nadh niacinamide redox status
    • Replies: 5
    • Forum: Scientific Studies
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