redox

The study below is one perhaps the most comprehensive review published to date, challenging the medical dogma that cancer is a genetic/mutation disease. As the study aptly explains, the evidence, spanning as far back as Otto Warburg's original work on this disease, is overwhelmingly in support...

One of the few studies out there that not only links cancer with impaired OXPHOS, but demonstrates directly the role of reductive stress (exemplified by the NAD/NADH ratio) in cancer's appetite for fats as fuel required for the cancer survival and proliferation/metastasis. It also once again...

Finally a study that provide me with some "ammo" during my arguments with people I know who work in the medical profession. A common topic in such arguments is the mainstream medical idea that it is almost impossible to have too much antioxidants and too little oxidation. In fact, to many...

Some excellent results from a human clinical trial. Namely, a combination of 3g niacinamide and 3g (calcium) pyruvate daily demonstrated significant therapeutic effect in patients with already established glaucoma. I can't access to actual study link on JAMA, but I suspect the mechanism of...

What should a true metabolism look like? What should we even look at? I dived a bit deep on this one and hopefully it provides answers for some. I'm discussing redox couples, such as NAD/NADH, GSH/GSSG and cysteine/cystine and how they affect energy production, ROS, hormone and neurotransmitter...

A hugely popular tenet of the "rate of living" theory is that the higher the metabolic rate the more reactive oxygen species (ROS) an organism produces. ROS elevation has already been implicated in a host of chronic disease including diabetes, CVD, cancer, neurological conditions and even mental...

A neat little study, which demonstrates once again the crucial role of energy and optimal redox status in a public health issue that has now reached catastrophic proportions. Namely, alcohol-related morbidity and mortality. Those have always been an issue in any developed country but since the...

Another great study demonstrating both the therapeutic potential of vitamins as well as the metabolic/redox nature of cancer. As I mentioned in some of my podcasts, vitamin K2 (MK-4) is currently in clinical trials for treating/preventing a number of different cancers, especially liver cancer...

As many forum users know, I have been interested in the Randle Cycle (glucose/fat competition for oxidation) for quite some time. The topic of limiting fatty acid oxidation (FAO) and promoting glucose oxidation is pretty central to the metabolic theory of health. Peat has written many times on...

It look like Linus Pauling may have the last laugh after all. The studies below show that high-dose IV therapy with vitamin C dramatically increases survival of several highly lethal cancers (e.g. pancreatic). Even the lead author is in disbelief and says the results are unheard of...

Another great example of "synchronicity" (Synchronicity - Wikipedia) happened today. Two separate but related studies, with similar organisms, popped up today in my mailbox. One of them (at UCDavis) shows that the redox status in favor of oxidation, and thus high reactive oxygen species (ROS)...

A great study, which shows that low-dose DHEA in the range discussed here on the forum (about 15mg daily) not only completely reversed the reductive stress seen in very old mammals but put the aging animals in an even more oxidized state than their very young counterparts. This study matches...

As many forum users have probably heard on the news, alcohol abuse is now a leading cause of death in young people under 35. It is projected to soon surpass drug overdose as a cause of death in this demographic. Millennials are dying of alcohol-related liver disease at increasing rates The...

This is yet another recent study showing that medicine may finally be getting on the right track. Similar to the human study with doxycycline and breast cancer I just posted, confirms again what has been known and fraudulently suppressed for almost a century. Namely, the Warburg "effect" is as...

Interesting study on using the redox properties of MB as a way to store electrons and then extract them as needed - i.e. the primary mechanism behind any modern battery. https://onlinelibrary.wiley.com/doi/abs/10.1002/celc.201801097 This bright blue dye is found in fabric: Could it also power...

It seems modern medicine is slowly starting to recognize the role of energy in organ health, and more specifically the role of NAD/NADH ratio in variety of diseases long thought to be mostly mechanism in origin. A few months ago, I posted a study on raising NAD levels with nicotinamide riboside...