redox homeostasis

  1. Hans

    An optimal metabolism: a look at the furnace within

    What should a true metabolism look like? What should we even look at? I dived a bit deep on this one and hopefully it provides answers for some. I'm discussing redox couples, such as NAD/NADH, GSH/GSSG and cysteine/cystine and how they affect energy production, ROS, hormone and neurotransmitter...
  2. haidut

    Estrogen As The Main Cause Of Cancer And Its Progression

    I think many of the forum users here know about the infamous study that generated a lot of controversy on "scientific" forums like Reddit. It basically showed that the Warburg Effect (overproduction of lactate) is not just an effect but a direct cause of cancer. So, as the top rated comment on...
    • haidut
    • Thread
    • cancer estrogen estrogen receptor fatty acid oxidation glycolysis hif hif-1 hypoxia lactate lactic acid mitochondria nad/nadh pdh pdk pyruvate randle cycle redox homeostasis warburg cause warburg cycle warburg effect
    • Replies: 18
    • Forum: Scientific Studies
  3. haidut

    Inosine Increases NAD/NADH Ratio And Reduces Systemic Inflammation

    Yet another great study on inosine. It shows that a HED of just 8mg/kg administered just twice daily increased the NAD/NADH ratio by a whopping factor of 15 (see attached screenshot). While inosine itself is neither a precursor to NAD (like niacinamide) nor is it an oxidizing agent, I think its...
    • haidut
    • Thread
    • inflammation inosine nad nad/nadh nadh raio redox homeostasis sepsis
    • Replies: 69
    • Forum: Scientific Studies
  4. haidut

    Riboflavin As The Next Generation Prebiotic Supplement

    This is a very good study IMO because it highlight that, as Ray has said many times, the microbial balance in the colon depends on the redox state of the organism. So, the solution to microbiome imbalance is probably not to ingest cupsfuls of bacteria but to improve the oxidative state of the...
    • haidut
    • Thread
    • microbiome prebiotic redox homeostasis riboflavin vitamin b2
    • Replies: 9
    • Forum: Scientific Studies
  5. P

    Dietary lipids modify redox homeostasis and steroidogenic status in rat testis.

    http://www.ncbi.nlm.nih.gov/pubmed/18549927 OBJECTIVE: The present study explored the effect of dietary oils on lipid composition, antioxidant status, and the activity of the main steroidogenic enzymes in the testis. METHODS: Forty Wistar rats were randomly assigned to one of four groups (n =...
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