pufa

  1. haidut

    Delirium (and Dementia/AD) Is Caused By Inability To Oxidize Glucose

    Ray has written about the metabolic origins of Alzheimer disease (AD) and I posted quite a few studies on the links between AD and PUFA metabolites as well as insulin resistance in the brain. I even mentioned on one of Danny Roddy's shows that there is a proposal by NIH to reclassify AD as...
    • haidut
    • Thread
    • ad alzheimer's delirium dementia ffa glucose insulin metabolism niacinamide pufa
    • Replies: 7
    • Forum: Scientific Studies
  2. haidut

    PUFA Is Vital For Cancer Progression; Restricting PUFA Can Be Therapeutic

    I don't think the findings of this study will come as a surprise to forum members but I think it is important to post it here as it is one of the few studies that points directly the finger at PUFA and calls it out by name. It is also the first study I have seen stating that reducing PUFA...
    • haidut
    • Thread
    • angiogenesis cancer cox diet omega-6 pufa restriction seh
    • Replies: 1
    • Forum: Scientific Studies
  3. haidut

    Low-dose Aspirin As Treatment For Kidney Disease / Failure

    Just wanted to post here as diabetes is perhaps the most common chronic disease in the world and many diabetes sufferers have kidney disease, which is considered irreversible. However, as this clinical trial states (and as Peat said as well), the kidney damage seems to be due to inflammation...
    • haidut
    • Thread
    • aspirin cox diabetes inflammation kidney disease kidney failure pufa treatment
    • Replies: 20
    • Forum: Scientific Studies
  4. haidut

    Another Study Links PUFA To Alzheimer Disease (AD)

    I posted some studies a few months ago, which showed that PUFA metabolites are elevated in patients with AD, and that blocking PUFA metabolism can reverse the pathology (in an animal model). Increased Pufa Oxidation May Be Biomarker For Alzheimers Blocking PUFA Metabolism May Reverse Alzheimer...
    • haidut
    • Thread
    • alzheimer's dha disease epa metaboic omega-3 pathology pufa
    • Replies: 5
    • Forum: Scientific Studies
  5. Drareg

    Inhibition Of Sperm Motility And Agglutination Of Sperm Cells By Free Fatty Acids In Whole Semen

    Interesting....... "The effects of a serial dilution of linoleic acid on human spermatozoa in whole semen was tested on 21 semen samples obtained from 11 normal volunteers. The minimal concentration of linoleic acid required to stop the movement of at least 75% of the moving sperm ranged from 1...
    • Drareg
    • Thread
    • free fatty acids infertility linoleic acid linolenic acid pufa sperm motility study
    • Replies: 6
    • Forum: Scientific Studies
  6. haidut

    PUFA Is Estrogenic And Androgen/Progesterone Antagonist

    As Peat mentioned many times and I discussed on Danny Roddy's shows, PUFA is a powerful endocrine disruptor. As such, it has direct effects on steroids and expression of steroids receptors in cells that go beyond its metabolism into the inflammatory mediators (even though those amplify the...
    • haidut
    • Thread
    • androgen antagonist arachidonic arachidonic acid disruptor endocrine estrogenic progesterone pufa
    • Replies: 2
    • Forum: Scientific Studies
  7. haidut

    Inhibition Of PUFA Metabolism (LOX) Trigger Immediate Apoptosis In Prostate Cancer

    These studies show that PUFA has both direct (linoleic) and secondary (through LOX) stimulating effect on prostate cancer growth, independently of any hormones. Inhibiting the LOX-5 pathway led to immediate growth arrest and apoptosis of prostate cancer cells. The important message for both...
    • haidut
    • Thread
    • apoptosis arachidonic growth immediate linoleic lox prostate cancer pufa
    • Replies: 18
    • Forum: Scientific Studies
  8. R

    Unsaturated Fats Role In Non-alcoholic Fatty Liver Disease

    At 2 minutes and 3 seconds
    • ReSTART
    • Thread
    • efa deficiency liver disease nafld pufa
    • Replies: 5
    • Forum: Fats
  9. M

    Soybean Oil Consumption: 10 G Per Year In 1909 Vs. 11.6 Kg Per Year In 1999

    I needed some numbers on PUFA consumption and found this study: Blasbalg et al. (2011) Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century Here, a few excerpts: "[...] To our knowledge, no estimate of changes in the n23 or n26 tissue status...
  10. Constatine

    Vitamin K2 Protective Against Pufa

    Medicines and Vegetable Oils as Hidden Causes of Cardiovascular Disease and Diabetes. - PubMed - NCBI BACKGROUND: Positive associations have been observed between cardiovascular disease (CVD) and type 2 diabetes mellitus (DM), but their causal relationship has not been clarified. Nevertheless...
  11. J

    Low Fat Vs Saturated Fat To Reduce PUFA Stored In Tissue: What Is The Best Strategy?

    I am a bit confused by the constant back and forth regarding PUFA depletion techniques (no fat) versus adequate saturated fat in ones diet. I understand self experimentation is the best way but am eager to hear some feedback from those who feel one is superior.
    • Jsaute21
    • Thread
    • diet low-fat diet pufa saturated fat
    • Replies: 6
    • Forum: Fats
  12. P

    Excess Linoleic Acid Increases Collagen I/III Ratio And “Stiffens” The Heart Muscle Following High F

    Excess Linoleic Acid Increases Collagen I/III Ratio and “Stiffens” the Heart Muscle Following High Fat Diets Abstract Controversy exists on the benefits versus harms of n-6 polyunsaturated fatty acids (n-6 PUFA). Although n-6 PUFA demonstrates anti-atherosclerotic properties, survival...
  13. Elie

    Study Concluded Replacing Dairy Fat With PUFA Calories Decreases CVD Incidence. Legit?

    Here is the abstract. Wonder if anyone has access to full text. I'd like to read the methodology. Dairy fat and risk of cardiovascular disease in 3 cohorts of US adults. - PubMed - NCBI Abstract BACKGROUND: Few prospective studies have examined dairy fat in relation to cardiovascular disease...
    • Elie
    • Thread
    • cvd dairy pufa study
    • Replies: 15
    • Forum: Diet
  14. haidut

    DHEA (and Other Androgens) Deplete EFA (PUFA) And Increase SFA

    A human study and as such very relevant. The dose of DHEA used was high (200mg), but androgens derived from DHEA have the same (and even more potent) effects in much lower doses, so low-dose DHEA should have similar (if not even better) effect. Yet another indication that androgens are...
    • haidut
    • Thread
    • androgens cholesterol dhea efa efa deficiency pufa reduction study
    • Replies: 10
    • Forum: Scientific Studies
  15. P

    Prolonged Niacin Treatment Leads To Increased Adipose Tissue Polyunsaturated Fatty Acid Synthesis

    This regards niacin. I don't know if would also apply to niacinamide, hence posting it here to get opinions. http://www.jlr.org/content/early/2014/10/15/jlr.M051938.full.pdf
  16. tonto

    "Unsaturated Fats Linked To Longer Healthier Life" - Harvard Gazette

    I haven't read the JAMA article referenced, but wondering what people think of this... Unsaturated fats linked to longer, healthier life Consuming greater amounts of unsaturated fats is associated with lower mortality, according to a study from Harvard T.H. Chan School of Public Health. In a...
    • tonto
    • Thread
    • lifespan longevity pufa
    • Replies: 48
    • Forum: Cholesterol
  17. tyw

    Endotoxin And Fat Consumption

    I wanted to state a couple of opinions regarding endotoxin in the context of 3 papers: (a) Dietary oil composition differentially modulates intestinal endotoxin transport and postprandial endotoxemia (Mani et. al., 2013) (b) High Fat Intake Leads to Acute Postprandial Exposure to Circulating...
  18. Dan W

    Effects Of Beef Production Method And Breed On Fat Content

    Here's an interesting study by Kraft et al (no relation to the mac-and-cheese empire, I presume): Extensive Analysis of Long-Chain Polyunsaturated Fatty Acids, CLA, trans-18:1 Isomers, and Plasmalogenic Lipids in Different Retail Beef types SFA content: PUFA content: I conclude from it...
    • Dan W
    • Thread
    • beef diet fat pufa study
    • Replies: 6
    • Forum: Meat
  19. O

    40 Yr-old Study On Fats Resurfaces In BMJ

    I jsut got sent this link, makes interesting reading, especially some of the comments... This study 40 years ago could have reshaped the American diet. But it was never fully published.
  20. haidut

    Eating PUFA Instead Of Butter Increases Overall Death Rates And CVD

    This is actually a human study and the sad part is that the study was actually done 50 years ago. Why was this data kept unpublished for so long is hard to explain but at least the truth is coming out. Note how the popular press title is worded carefully to avoid casting PUFA in completely...
    • haidut
    • Thread
    • cvd death heart attack increases linoleic acid pufa risk study
    • Replies: 2
    • Forum: Scientific Studies
Back
Top Bottom