ptsd

  1. C

    Is Propranolol Unique Or Can Other Beta Blockers Be Used For PTSD, Bad Memories etc...?

    There are lots of potential applications for this lipophilic and non-selective beta blocker. Can any other beta blockers be used or is it special? Metoprolol seems to be similar (although more selective and less lipophilic). Could it probably be substituted and work as well?
  2. haidut

    Elevated serotonin (5-HT) and norepinephrine (NE) drive nightmares in PTSD

    More than a quarter of all military/veteran personnel are estimated to have some form/level of PTSD, regardless of whether those soldiers have seen combat or not (e.g. Coast Guard members also have high rates of PTSD). Despite the obvious link to severe stress, medicine continues to claim that...
    • haidut
    • Thread
    • 5-ht nightmares norepinephrine ptsd serotonin sleep ssri stress
    • Replies: 3
    • Forum: Scientific Studies
  3. haidut

    Serotonin (5-HT) drives fear and conditions such as anxiety/PTSD

    Conversely, blocking 5-HT or lowering its synthesis can probably cure most fear-based conditions such as generalized anxiety disorder (GAD), PTSD, psychotic conditions (e.g. schizophrenia), etc. At least, those are the findings of the study below, which demonstrated that animals completely...
  4. D

    Need advice for bad ptsd & anxiety

    Hey everybody, This might be a little long winded, but I am currently fighting daily demons of ptsd & anxiety which is slowly killing me. My sleep is bad, I'm constantly in fight or flight which is ruining my stomach and I'm constantly angry. Ive been chain smoking tobacco & weed to get short...
  5. A

    Post-Traumatic Stress Disorder as an Endothelial Disease: Insights From COVID-19

    SARS-CoV-2 virus, the etiologic agent of COVID-19, has affected almost every aspect of human life, precipitating stress-related pathology in vulnerable individuals. As the prevalence rate of posttraumatic stress disorder in pandemic survivors exceeds that of the general and special populations...
  6. C

    Info about/experience with Strattera/Atomoxetine?

    I haven't been able to find any articles Ray has about Strattera/Atomoxetine/Norepinephrine Reuptake Inhibitors. I'd like to know what people may know about this, and potential substitutes/alternatives. I was diagnosed with ADHD in my early 20s and have been on and off ADHD meds for over 15...
  7. Mr Joe

    Combo High Dose (B1 + Cypro + B3) + T3 for recovery

    2 Years ago Symptoms : All day Anxiety, Depression Emergency state. Any bad thought would cause belly contraction and a cycle of stress diffucult to calm. Sleepness, GERD intense headaches when doing mental effort. I am understanding now that all of these could be symptoms of very low metabolism...
    • Mr Joe
    • Thread
    • anxiety cortisol cyproheptadine high-dose metabolic disorder ptsd serotonin stress thiamine vitamin b1
    • Replies: 12
    • Forum: Mental Issues
  8. haidut

    Serotonin (and SSRI drugs) can cause anxiety and PTSD

    Yet another great study exposing just how much of a "happy hormone" serotonin really is. As usual, the popular press article does everything possible to avoid pointing the finger at serotonin and even engages in misdirection. For example, it says that SERT is the main target of drugs like...
  9. haidut

    Stress (cortisol) Can Cause ANY Autoimmune Condition By Disrupting Gut Barrier

    A great new study that is not afraid to point out the paradox between mainstream medicine's claims of beneficial effects of cortisol and the reality of "autoimmune" conditions more often than not being associated with elevated levels of CRH, ACTH and cortisol. The role of CRH as a causative...
    • haidut
    • Thread
    • autoimmune cause cortisol endotoxin inflammation leaky gut lps ptsd stress
    • Replies: 6
    • Forum: Scientific Studies
  10. md_a

    How Chronic Fear Results In Hypoxia In Tissues And Cancer In Humans Through Bohr Effect

    How Chronic Fear Results In Hypoxia in Tissues and Cancer in Humans through Bohr Effect Professor Sir Sorush Niknamian; Dr. Somayeh Zaminpira Fear is a number of chain reactions in the brain that occurs when one encounters a potentially harmful stimulus. The amygdala is the part of the brain...
  11. haidut

    Serotonin Causes The Startle Response, And Likely PTSD As Well

    As my readers know, I have posted quite a few threads in the past on the topic of PTSD. It is a condition that affects up to 30% of current/former military members, and is considered a condition of unknown cause and without treatment. Current treatment options consist of mostly symptom...
    • haidut
    • Thread
    • 5-ht cause drive mental disorder mental illness ptsd serotonin startle startle response trauma
    • Replies: 20
    • Forum: Scientific Studies
  12. haidut

    Chronic Stress (adversity) Lowers Dopamine And Causes Mental Illness

    The evidence for the role of chronic stress in virtually every health condition doctors have a name for just keeps on accumulating. Unfortunately, even in this latest study the scientists keep insisting that there is some mysterious and unquantifiable difference between chronic stress...
    • haidut
    • Thread
    • adversity anxiety cause chronic stress cortisol depression disease dopamine mental disorder mental illness pathology psychosis ptsd schizophrenia serotonin suicide
    • Replies: 6
    • Forum: Scientific Studies
  13. haidut

    Estrogen Is A Stress Hormone, It Can Both Trigger And Potentiate The Effects Of Stress

    I was quite surprised to see this article in WebMD - a website that is bastion of mainstream medicine. It regularly promotes dogmas related serotonin, estrogen, oxytocin, growth hormone, etc and the myriad of "benefits" these substances bestow upon humans. However, a bit of truth apparently...
    • haidut
    • Thread
    • cause depression estradiol estrogen female hormone mental illness potentiate ptsd stress trigger
    • Replies: 11
    • Forum: Scientific Studies
  14. haidut

    Insects Can Feel Both Acute And Chronic Pain, Can Even Develop Insect-PTSD

    Probably not many forum users know it, but to this day surgery on babies or other painful procedures is often performed without anesthesia. The rationale for this horrific torture is that the nervous system of babies is not developed yet, so they don't feel pain. It takes a special kind of...
    • haidut
    • Thread
    • acute animals chronic feel gaba glycine inhibitory insects neuropathic pain ptsd
    • Replies: 4
    • Forum: Scientific Studies
  15. haidut

    Blocking Stress (adrenaline) Just Once Cures PTSD And Maybe Any Mental Disorder

    This is a remarkable study, which once again implicates extreme stress in the pathology of mental health disorders, specifically anxiety and PTSD. Just a few days ago I posted a study showing a high cortisol (C) / testosterone (T) ratio is likely causative in PTSD. People with high C/T ratio...
    • haidut
    • Thread
    • adrenaline anxiety beta blocker cause cure fear mental disorder mental health mental illness propranolol ptsd stress trauma treat
    • Replies: 96
    • Forum: Scientific Studies
  16. haidut

    High Cortisol And Low Testosterone Likely Drive PTSD

    As the article below states, 20%+ of service members come back with PTSD. It is a devastating mental condition that makes patients not only unable to participate meaningfully in society but often drives them to violent and homicidal/suicidal behavior. Given the roles of cortisol and serotonin in...
    • haidut
    • Thread
    • acute cause chronic cortisol drive elevated high ptsd stress trauma
    • Replies: 4
    • Forum: Scientific Studies
  17. haidut

    Pregnenolone Is A Potent (functional) Endotoxin (TLR4) Antagonist

    It seems that pregnenolone is finally starting to look exciting to the medical industry. In addition for its intensive studies for a variety of mental issues, now studies are coming out demonstrating its endotoxin (LPS) antagonism effects. As most forum users know, endotoxin exerts its effects...
    • haidut
    • Thread
    • alcoholism allopregnanolone alzheimer's antagonist cvd depression endotoxin epilepsy immune system inflammation lps ms multiple sclerosis pregnenolone ptsd schizophrenia sepsis tlr4 tnf
    • Replies: 10
    • Forum: Scientific Studies
  18. haidut

    PTSD / Trauma Is Contagious, Can Be Transmitted Via Odor/pheromones

    This is an amazing study, which goes a long way in confirming what has been anecdotally known for centuries - bad experiences affect not only the individual experiencing them but everybody else this traumatized individual is in closed contact with. With one exception - psychopaths - who are...
    • haidut
    • Thread
    • contagious cortisol crh estrogen infectious oxytocin ptsd stress transmit trauma
    • Replies: 73
    • Forum: Scientific Studies
  19. haidut

    Intrusive / Unwanted Thoughts Due To Low GABA Signalling

    Peat has mentioned GABA quite a few times in his articles and its role as the chief inhibitory signal in the body, protecting both brain cells and peripheral tissues/organs from excitotoxicity caused by PUFA, glutamate, estrogen, stress, etc. But the role of GABA is especially prominent in the...
    • haidut
    • Thread
    • anxiety depression gaba intrusive thoughts psychosis ptsd schizophrenia unwanted thoughts
    • Replies: 47
    • Forum: Scientific Studies
  20. T

    Blocking PTSD With Doxycycline

    With likely implications around learned helplessness. "We find that recall of threat memory, measured with fear-potentiated startle 7 days after acquisition, is attenuated by ~60% in individuals who were under doxycycline during acquisition... Our findings support an emerging view that...
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