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protein synthesis

  1. haidut

    PUFA Is Directly Catabolic (without Cortisol/estrogen), SFA Is Anabolic

    I posted a few studies about PUFA potentiating the stress response and cortisol synthesis, even without the typical elevations of ACTH present in organic stress reactions. Saturated fats block that pro-stress effects of PUFA...
  2. haidut

    Inosine Increases ATP And Reverses NAFLD (and Likely Other Liver Disease)

    As I mentioned in another recent thread on inosine and serotonin/cortisol, many pathologies are simply signs/symptoms of inefficient ATP synthesis and restoring proper synthesis or replenishing ATP levels through precursors often reverses the pathology. These two studies below show that fatty...
  3. haidut

    Glycine Is Directly Anabolic AND Anticatabolic For The Muscle

    I posted a few interesting studies about glycine in the past. Among the interesting properties are lowering cortisol, increasing DHT synthesis, improving insulin sensitivity, and serving as a biomarker of stress. Glycine Powerfully Lowers Cortisol Glycine Strongly Upregulates 5-alpha Reductase...
  4. haidut

    The Anabolic Effects Of Pregnenolone

    I posted a few studies showing pregnenolone has anti-cortisol and anti-estrogen effects, which make it anti-catabolic by definition. However, older studies referred to pregnenolone as an anabolic steroid and some of them examined its anabolic effects. While pregnenolone was not as potent as...
  5. haidut

    Even protein distribution in meals is healthier than a bolus

    This may sound rather obvious, but until at least 2010 the consensus "expert" opinion was that protein was protein no matter how and when you consume it. In fact, some "nutritionists" were advocating eating most of the protein at night. A high dose of protein will drastically lower blood sugar...
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