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  1. haidut

    Finasteride causes gut inflammation, high serotonin, low dopamine; allopregnanolone may treat

    A great new study, which goes a long way towards explaining the dreaded post-finasteride syndrome (PFS). Currently, medicine does not recognize PFS as a formal disease and in fact attempts to gaslight the patients with PFS into believing they are simply mentally ill and in need of SSRI drugs...
  2. W

    Progesterone inhibits 5ar?

    Whenever I took progesterone I felt anxious for several days, then I came across this article today: --- Effects of the anti-androgen finasteride on 5 alpha-reduction of androgens in the presence of progesterone in human gingival fibroblasts: modulatory actions of the alkaline phosphatase...
  3. B

    Need help with some serious medical issues after from clomid and hcg blood pressure going crazy

    So update, I know it's been a LONG time and also want to tell everyone that I'm cured from PFS great news. But with that being said I'm come into cross with a lot of health problems from that point as was really looking for some help. My course 6 months of hcg per protocol and finished with a...
  4. haidut

    AlloP - Liquid Allopregnanolone For Lab/R&D

    Just a quick announcement that we have replaced the 5α-DHP in our store with allopregnanolone. The main reason for switching over to allopregnanolone is that we always wanted to provide that steroid right from the start, however we could not find a lab willing to synthesize it. Thus, 5α-DHP...
  5. Hans

    PFS: 3a and 3b-HSD theory

    In this Friday's newsletter, I postulated the theory that it might not necessarily be the 5-AR type 1 or 2 enzymes that are defective, but rather 3a and 3b-HSD. I quote from the newsletter: "Most people think that PFS is caused by downregulated 5AR, but a lot of people actually have normal DHT...
  6. fever257

    HCG And Proviron - Are They Safe?

    Hello, I need to inquire about the safety of two separate drugs/steroids that I'm inclined to take. Both of these would be to optimize hormonal issues engendered by 5-AR blocking via finasteride. I'm positive that I need to push my system artificially with a drug in order to heal my hormones...
  7. S

    DHT And Reversing Androgen-receptor Deficiency

    I'll make this thread as short as I can: A few years ago, I ran gear stupidly and developed what seems to be identical to Post-finasteride syndrome (deca is notorious for causing problems). I've read Proviron/DHT creams seem to reverse the problem. The problem is, I can't seem to find any...