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p4

  1. haidut

    Cells preferentially accumulate Pregnenolone (P5), Progesterone (P4), and DHEA

    A study not directly dealing with disease, though its findings are probably relevant for all diseases. It demonstrates that in addition to the so-called "active transport", which we have been told is the dominant mechanism in steroid absorption and intracellular relevance, there also exists a...
    • haidut
    • Thread
    • androgens cortisol dhea estrogen intracellular p4 p5 pregnenolone progesterone uptake
    • Replies: 2
    • Forum: Scientific Studies
  2. P

    Progesterone receptors and serotonin levels in colon epithelial cells from females with slow transit constipation (P4 lowers SERT)

    Abstract link to study Background: Females with slow transit constipation (STC) exhibit progesterone receptor (P4R) overexpression in colon muscle that impair their contractility. These studies examined whether these patients have an overexpression of P4R in epithelial cells and...
    • Peeno
    • Thread
    • 5ht constipation p4 progesterone sert
    • Replies: 3
    • Forum: Progesterone
  3. haidut

    Pregnenolone Is As Potent As Progesterone As An (irreversible) Aromatase Inhibitor

    Progesterone does not need an introduction here and most people are likely aware of its antiestrogenic effects. A few years ago, I posted a thread with an old French study showing that a 500mg daily dose pregnenolone completely blocked estrogen's effects - an effect identical to what...
    • haidut
    • Thread
    • aromatase aromatase inhibition estradiol estrogen fsh irreversible p4 p5 pregnenolone progesterone
    • Replies: 32
    • Forum: Scientific Studies
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