oxidative metabolism

  1. Hgreen56

    Has Anyone Ever Actually Heard Dr Peat Recommend A High Carb Diet?

    Has anyone ever actually heard Dr Peat recommend a high carb diet? The only time I've ever heard him questioned about optimal macro ratios, he said he doesn't know, and that 33/33/33 might be good. That's hardly high carb. In fact, the only time I've heard him use the words "high carb," is when...
  2. haidut

    Morphostasis Theory Of Immunity Confirmed - Body Treats Heart Attack Like Viral Infection

    Peat has touched upon his views of the immune system in several articles, mostly related to autoimmune disease. In his view, the role of the immune system is not so much to "attack" foreign pathogens that threaten the organism, but is more akin to sanitation workers who clean up trash and other...
  3. haidut

    Children Have More Energy And Recover Faster Than Elite Endurance Athletes

    While endurance exercise is hardly the healthiest form of physical activity, triathlon runners are known for their ability to quickly clear lactate out of the blood and metabolite it back into glucose. The ability to handle lactate is good metric of metabolic health and the pyruvate/lactate...
  4. haidut

    Inosine Powerfully Stimulates Mitochondriogenesis, Oxidative Metabolism & Cell Differentiation

    Yet another absolutely great study on inosine. It shows that not only can inosine replenish ATP (as shown in the previous studies I posted) but it can inhibit excessive glycolysis, lower lactate, and dramatically improve oxidative metabolism - effects which are key driver of cell differentiation...
  5. haidut

    Palmitic Acid (palmitate) Strongly Increases Oxidative Metabolism

    This is yet another thread as a follow up on the recent posts about plamitic acid inhibiting fatty acid oxidation and having therapeutic roles in cancer, diabetes and all other disease characterized by elevated/abnormal fatty acid metabolism. Palmitic Acid (palmitate) Is A Fatty Acid Oxidation...
  6. S

    Fibroblasts Shuttle Glutamate, Arginine Into Cancer Cells And Promote Glycolysis

    Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism Cancer-associated fibroblasts release exosomes that both deliver nutrients to cancer cells and inhibit oxidative phosphorylation. Exosomes from fibroblasts can supply an amino acid called glutamine and other...
  7. P

    Some Pentoxifylline Studies

    Pentoxifylline Reverses Oxidative Mitochondrial Defect in Claudicating Skeletal Muscle The effect of pentoxifylline on filterability of normal red blood cells and their adhesiveness to cultured endothelial cells - Springer Pentoxifylline Neuroprotective Effects Are Possibly Related to Its...
  8. haidut

    MitoLipin - Liquid Saturated Phosphatidylcholine (PC) Mix

    Ray has written extensively about the mitochondria and its crucial role in health. The structure and contents of the mitochondria undergo extensive change as part of the aging process and one of the most important constituents of mitochondria is the lipid cardiolipin (CL). CL is crucial for the...
  9. haidut

    Aging Tied To Loss Of Oxidative Capacity; Stress Has Same Effect

    In yet another confirmation of Ray's metabolic theory of everything (TOE), this study found that aging is associate with a shift from oxidative to reductive state in the cell. More importantly, the study found that stress has the same effects as the aging process - i.e. stress is a form of...
  10. haidut

    Low Dose DHEA Robustly Increases Oxidative Metabolism

    I posted another study recently that showed low doses DHEA treatment increased T and DHT levels in rats and had the same beneficial effects as exercise. The human equivalent dose used was <15mg per day. These studies shows that a low dose DHEA dramatically improves oxidative metabolism in liver...
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