omega-6

  1. Lewis Acid

    Dr. Chris Knobbe - 'Diseases of Civilization: Are Seed Oil Excesses the Unifying Mechanism?'

    Nothing new for this group - nice to see more recognition of the PUFA topic; a decent presentation as well. Dr. Chris Knobbe is an ophthalmologist and Associate Clinical Professor Emeritus, formerly of the University of Texas Southwestern Medical Center, in Dallas, Texas. He is also the...
  2. haidut

    Glucocorticoids may increase inflammation in the long run

    Glucocorticoids (both bioidentical and synthetic) are some of the most widely used drugs in the clinical setting, as well as in outpatient treatment for all sorts of ailments - i.e. autoimmune conditions, joint pain, post-operative inflammation, asthma, and even infectious diseases such as...
  3. haidut

    PUFA promote torpor / hibernation, decrease lifespan

    Not many studies on this topic, but here is one that will hopefully satisfy my critics who keep complaining that there is no evidence for the anti-metabolic, pro-hibernation effects of PUFA. Apparently, PUFA is sought after by hibernating animals (but even they consume it within very tightly...
  4. haidut

    PUFA are potent immunosuppresive agents

    Just a quick post for all those PUFA/fish-oil lovers who keep sending me hate-mail about the "incredibly beneficial" omega-3, and even omega-6 (e.g. some athletes/bodybuilders tout arachidonic acid as a natural "anabolic agent"). As the study below discusses, all PUFA, but especially omega-3...
  5. haidut

    PUFA May Be A Major Factor In Sterility

    Just minutes ago I made a post about PUFA driving obesity, inflammation, and liver damage in diabetes II patients. The omega-6 fatty acid DLGA (a metabolite of linoleic acid) was the main pathological factor examined in that study. Now, a new study study demonstrates that DLGA may also cause...
  6. haidut

    PUFA Increases Risk Of All Cancers, Especially Prostate

    The bad news for PUFA just keep on coming. There seems to be no health pathology that PUFA does not promote, even indirectly. The study below demonstrates that BOTH omega-3 and omega-6 increase risk of ANY cancer and death from it, but specifically the risk of aggressive prostate cancer. It is...
  7. haidut

    Diet (PUFA) Causes Inflammatory Bowel Disease (IBD)

    Rates of inflammatory bowel diseases (IBD) such as ulcerative colitis (UC) have been steadily increasing and predominantly so in the youngest cohorts studied. The official cause of UC is of course "unknown" even though the public health authorities do admit that an environmental agent is most...
  8. haidut

    PUFA Is A Cancer "sensitizer"

    A neat study, which demonstrates that in addition to its direct carcinogenic effects, PUFA is also a cancer "sensitizer" - i.e. is triggers the development of cancer in the presence of less-than-healthy chemicals that are relatively harmless by themselves. This sensitizing role of PUFA seems to...
  9. haidut

    PUFA Increases Risks Of Skin Cancers

    As the study says - not total fat but its composition in the diet is what drives (skin) cancer risk. And as expected, PUFA "shines" once again. What is particular good about this study is that it exposes both omega-6 and omega-3 as cancer-promoting. Omega-3 has been the defense of last resort...
  10. haidut

    PUFA May Drive Obesity, Insulin Resistance, Liver Issues In Diabetes II Patients

    Yet another study where the message is clear - there is nothing "essential" about the PUFA we are bombarded with from all directions be that diet, medical interventions, household products, etc. What makes this study particularly relevant is that PUFA ingestion actually is promoted as one of the...
  11. haidut

    America’s Favorite Oil Causes Diabetes, Obesity, Autism, And Liver / Brain Disease

    A series of shockingly direct studies that do not shy away from pointing the finger at the real villain in modern public health history - PUFA, and more specifically the "essential" linoleic acid (LA). As the studies demonstrate, soy oil has strikingly detrimental effects on metabolic health and...
  12. haidut

    PUFA Enhance Glucocorticoid (cortisol) Signalling

    I posted some studied in the past on the estrogenic and pro-cortisol effects of PUFA, as well as the pro-androgen effects of SFA. One of those studies showed that PUFA increases cortisol synthesis even in the absence of ACTH, which suggests that they may have pituitary hormonal-like effects...
  13. haidut

    PUFA As The Main Cause Of Cardiovascular Disease (CVD) And Organ Failure

    Some more evidence on the role of PUFA as a big factor in CVD. While the evidence is not widely discussed on mainstream media, and a few saboteur attempt against coconut oil have recently been published, nonetheless a few "runaways" do make it to front page news and we have posted them on the...
  14. haidut

    Elevated PUFA In Blood Drive Metabolic Syndrome And Diabetes

    Some good evidence on the role of PUFA and inflammation in obesity and diabetes. The findings that FFA are elevated in obese people is not surprising and even mainstream medicine has wisened up to that fact. The surprising (for the authors) part was that unsaturated fats were involved in the...
  15. haidut

    PUFA Is Essential For Cancer, Aspirin And/or Blocking Estrogen Therapeutic

    While this study is not something that will come as surprising to the forum members, I decided to post it because it directly points the finger at BOTH omega-6 and omega-3 unsaturated fats as causes of GI and pancreatic cancers. While the study includes the standard "disclaimer" that omega-3...
  16. haidut

    PUFA Is Directly Catabolic (without Cortisol/estrogen), SFA Is Anabolic

    I posted a few studies about PUFA potentiating the stress response and cortisol synthesis, even without the typical elevations of ACTH present in organic stress reactions. Saturated fats block that pro-stress effects of PUFA...
  17. haidut

    PUFA Required/essential For Cancer; Stearic Acid Is A PUFA Antagonist & Anti-cancer

    Two studies showing that PUFA (linoleic) acid is essential for cancer development. As the studies show, cancer cells accumulate large quantities of oleic acid and the saturation index (SI) - i.e. ratio of stearic/oleic acids in erythrocytes (RBC) is very low in cancer. This SI can also be used...
  18. haidut

    The Carcinogenic And Estrogenic Effects Of PUFA

    Yet another study, which I decided to post because it is one of the few studies that directly points the finger at PUFA (and linoleic acid in particular - the nemesis of user @Travis) as the cause of breast, colon, prostate and other cancers. It also provides evidence for greatly increase serum...
  19. haidut

    PUFA Is Vital For Cancer Progression; Restricting PUFA Can Be Therapeutic

    I don't think the findings of this study will come as a surprise to forum members but I think it is important to post it here as it is one of the few studies that points directly the finger at PUFA and calls it out by name. It is also the first study I have seen stating that reducing PUFA...
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