obesity

  1. Mauritio

    Low Dopamine D2 receptor density leads to obesity and insulin resistance , D2 agonism may treat

    These studies show that the Dopmine D2 receptors are strongly involved in obesity and insulin resistance . 1. (Brain dopamine and obesity - PubMed) "Striatal dopamine D2 receptor availability was significantly lower in the ten obese individuals (2.47 [SD 0.36]) than in controls (2.99 [0.41]...
  2. Hans

    The high sugar model did not prove to be a good model of obesity

    Excess sugar consumption doesn't necessarily make you fat, if you have sufficient nutrients to use the carbs. "but the daily caloric intake was higher in the HS group in relation to the C and HFHS groups (HS: 92 ± 2.0 vs. C: 79.2 ± 2.6 and HFHS: 77.3 ± 1.7 kcal/day, p < 0.05)." And yet...
  3. haidut

    Glycine (and leucine) can treat fatty liver (NAFLD and NASH)

    A great new study that demonstrates the strong protective effects of glycine, alone or in combination with leucine, on preventing/treating various forms of fatty liver disease, as well as the obesity that often accompanies these conditions. One of the strong points of the study is that it also...
    • haidut
    • Thread
    • diabetes glycine inflammation leucine liver nafld nash obesity pufa
    • Replies: 3
    • Forum: Scientific Studies
  4. Tristan Loscha

    (EU) Committee for Medicinal Products for Human Use (CHMP) Assessment report: EnCyzix (Enclomifene)

    Treatment of hypogonadotropic hypogonadism (secondary hypogonadism) in adult men aged ≤60 years with a body mass index (BMI) ≥25 kg/m2 which has been confirmed by clinical features and biochemical tests in patients which have not responded to diet and exercise
    • Tristan Loscha
    • Thread
    • clomiphene enclomiphene hypogonadotropic hypogonadism luteinising hormone marketing authorisation obesity oestradiol serm tamoxifen testosterone
    • Replies: 3
    • Forum: Hormones
  5. haidut

    Obesity "paradox" Strikes Again - Protection Against COVID-19

    I suspect this one will not go down will with the "lean is always good" crowd, which consists predominantly of members of the medical profession. Aside from all the health risks of obesity for pretty much any chronic disease, the news over the last 6 months have been replete with warning from...
    • haidut
    • Thread
    • coronavirus covid-19 infection mortality obesity paradox protective virus
    • Replies: 9
    • Forum: Scientific Studies
  6. Hans

    The One Gut Bacterium You Have To Boost (and Here’s How)

    There is so much controversy over gut bacteria and if we should lower it or boost it or try to modulate it. Well, we have a gut microbiota whether we like it not, so we have to make the best of it. Lowering gut bacteria with antibiotics can be very helpful, but is rarely a long term solution...
  7. Drareg

    Obesity And COVID 19 Increased Risk Of Adverse Outcomes

    Most of the deaths from covid19 outside vulnerable groups were obese patients. This study is pretty damning, it seems this politically correct body positive PR campaign needs to stop, I’m not saying we need to shame people but we sure don’t need to glorify obesity. If governments genuinely...
  8. lvysaur

    Thymus Function: Higher In The Young/fat/female/Asian

    Population Distributions of Thymic Function in Adults: Variation by Sociodemographic Characteristics and Health Status http://www.self.gutenberg.org/articles/eng/mongoloid
    • lvysaur
    • Thread
    • asian east asian immunity obesity overweight persistence thymus
    • Replies: 12
    • Forum: Scientific Studies
  9. haidut

    Levothyroxine (T4) Monotherapy Often Ineffective For Hypothyroidism

    As most of my readers know, the currently approved therapy for hypothyroidism is levothyroxine (T4). While technically T3 and combined T4/T3 therapy are also approved by FDA, the former is only used in severe cases of myxedema and the latter is considered obsolete and a remnant of the days when...
    • haidut
    • Thread
    • fail hypothyroidism ineffective levothyroxine metabolic rate monotherapy obesity t4
    • Replies: 2
    • Forum: Scientific Studies
  10. haidut

    PUFA Makes Girls Fat / Lazy / Diabetic And Exercise Futile

    Just a few minutes ago I made a post about PUFA (from nuts) increasing risk of diabetes. I just came across another very similar study below. It found that PUFA consumption, in both mice and humans, makes them fat and highly sedentary while also increasing their diabetes risk. MUFA and SFA had...
  11. haidut

    PUFA May Drive Obesity, Insulin Resistance, Liver Issues In Diabetes II Patients

    Yet another study where the message is clear - there is nothing "essential" about the PUFA we are bombarded with from all directions be that diet, medical interventions, household products, etc. What makes this study particularly relevant is that PUFA ingestion actually is promoted as one of the...
    • haidut
    • Thread
    • diabetes fatty liver insulin resistance obesity omega-3 omega-6 promote pufa
    • Replies: 0
    • Forum: Scientific Studies
  12. Mauritio

    Serotonin Causes Obesity, Diabetes, Fibrosis,liver Damage ,increases Endotoxin And NO

    Inspired by this thread Serotonin/endotoxin/PUFA As Primary Causes Of Depression And Diabetes; Can Be Easily Blocked I was reading a few more recent studies on the detrimental effect of serotonin on ones health. It seems clear that by now it is known in medicine, that blocking it is highly...
    • Mauritio
    • Thread
    • diabetes endotoxin fibrosis nitric oxide no obesity serotonin tlr4 tph tph inhibitor
    • Replies: 7
    • Forum: Scientific Studies
  13. haidut

    Vitamin D Reduces Blood Sugar And Body Fat In Obese Women

    A neat study, albeit lasting much longer (about 1.5 years) than most other intervention studied with vitamin D. What makes this study particularly interesting is that it only used high doses vitamin D (60,000 IU once weekly) initially until blood levels rose into the normal range. It did not...
    • haidut
    • Thread
    • blood glucose cholecalciferol fat loss improve insulin resistance obesity prediabetes vitamin d vitamin d3
    • Replies: 2
    • Forum: Scientific Studies
  14. haidut

    Pre-natal Viagra Use Causes Offspring Hypertension And Maternal Diabesity

    The study looks weird at first glance - why would pregnant women take Viagra? After all, it is a drug initially developed for treating hypertension and erectile dysfunction (ED) in men. Well, the same misguided idea of using nitric oxide (NO) promoting drugs like Viagra to induce vasodilation...
    • haidut
    • Thread
    • cause diabetes hypertension obesity pah prenatal pulmonary arterial hypertension sildenafil viagra
    • Replies: 2
    • Forum: Scientific Studies
  15. haidut

    The Keto Diet Works Only For A Week, Then It Causes Obesity And Diabetes

    A great study that goes a long way towards dispelling the currently dominant dietary fad - the keto diet, as well as various other functionally equivalent diets such as Paleo, Warrior, intermittent fasting, etc. As the study unequivocally demonstrates, the reductions in blood sugar and weight...
    • haidut
    • Thread
    • cause cortisol diabetes diet drive keto low-carb obesity paleo
    • Replies: 35
    • Forum: Scientific Studies
  16. haidut

    America’s Favorite Oil Causes Diabetes, Obesity, Autism, And Liver / Brain Disease

    A series of shockingly direct studies that do not shy away from pointing the finger at the real villain in modern public health history - PUFA, and more specifically the "essential" linoleic acid (LA). As the studies demonstrate, soy oil has strikingly detrimental effects on metabolic health and...
    • haidut
    • Thread
    • autism cause corn oil diabetes nafld obesity omega-3 omega-6 parkinson pufa soy oil soybean oil
    • Replies: 0
    • Forum: Scientific Studies
  17. haidut

    Progesterone May Treat Diabetes, Obesity, And Metabolic Syndrome

    Interesting new study, which adds more to the already existing mountain of evidence for the benefit of progesterone in a variety of conditions of metabolic origin. While the study does not mention any specific doses, it is known that the receptor (PGRMC2) whose activation the study found to be...
    • haidut
    • Thread
    • diabetes heat heme metabolism mitochondria obesity pgrmc2 progesterone therapeutic treat
    • Replies: 6
    • Forum: Scientific Studies
  18. haidut

    Despite Striking Increase In Dieting And Exercise, Obesity Is Skyrocketing

    Maybe it takes a study like the one below to finally wake the public health authorities from their century-long slumber. I doubt there is a person alive today living in the Western world who has not been raised by the mantra "eat less and move more" as the single proven way to lose weight...
    • haidut
    • Thread
    • caloric restriction diet dieting exercise failure fasting obesity unsuccessful
    • Replies: 54
    • Forum: Scientific Studies
  19. haidut

    Endotoxin Has A G.E.L.D.I.N.G Effect, Causes Obesity And Hypogonadism

    A very interesting study proposing that the decline in gonadal function seen in obese/diabetic men is due to chronically elevated endotoxin levels in such people. The study calls this phenomenon (G)ut (E)dotoxin (L)eading to a (D)ecline (I)n (G)onadal function (GELDING) due to the remarkable...
    • haidut
    • Thread
    • castration diet endotoxin gelding high-fat hypogonadism inflammation leydig lps obesity tlr tlr4
    • Replies: 34
    • Forum: Scientific Studies
  20. haidut

    Serotonin (due To Bacteria) Is The Master Regulator Of Metabolism, Insulin Sensitivity, And Weig

    Over the last year I posted a number of studies demonstrating strong link between serotonin and chronic conditions such as obesity, insulin resistance, and even diabetes. Augmented capacity for peripheral serotonin release in human obesity...
    • haidut
    • Thread
    • 5-ht bacteria colon diabetes gut inflammation insulin resistance microbiome obesity pathological serotonin sibo tph
    • Replies: 31
    • Forum: Scientific Studies
Back
Top Bottom