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  1. A

    Niclosamide, a salicylic acid derivative, may treat vascular calcification

    https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8811128 Vascular calcification is a cardiovascular disorder with no therapeutic options. We recently reported that o-octanoyltransferase (CROT) suppression can inhibit vascular calcification in vivo and in vitro through amelioration of...
  2. A

    Niclosamide may be a therapeutic candidate for ALS

    Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron loss in the brain and spinal cord; however, its etiology is unknown, and no curative treatment exists. TAR DNA-binding protein 43 (TDP-43), encoded by TARDBP, is a genetic mutation observed in 2-5% of familial ALS...
  3. LadyRae

    Niclosamide for fat loss/ uncoupling

    Does anyone have any experience utilizing Niclosamide for fat loss via mitochondrial uncoupling? It is purported to have a similar action to DNP without the risks.... Thanks!
  4. haidut

    Type 2 Diabetes Can Be Treated By Mitochondrial Uncoupling

    The article claims that Type 2 diabetes is caused by fatty liver, and taking drugs that increase mitochondrial uncoupling can reverse the disease course. Aspirin, caffeine, saturated fat, etc should do the job of uncoupling just as well. http://news.rutgers.edu/research-news/a ... DIMWGeSz95...