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Serum endotoxin level is a reliable biomarker of liver disease
It looks like the interest in gut-derived pathogenic substances is steadily increasing in the medical field. After claiming for decades (and still doing so) that liver disease is either genetic in origin or driven mostly by sugar (especially fructose) consumption, now studies like the one below...- haidut
- Thread
- endotoxin fibrosis inflammation liver lps nafld nash tlr4
- Replies: 12
- Forum: Scientific Studies
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Activating FXR decreases PUFA in the liver
Very interesting study showing that activating the Farnesoid X Receptor results in lower levels of MUFA and PUFA in the liver. (Farnesoid X receptor - Wikipedia) Lowers levels of MUFA are brought on by downregulating genes like SCD1. "Elevated expression levels of SCD1 is found to be... -
Bromantane reduces liver fibrosis by 60%, kidney fibrosis by 50%
This study shows that Bromantane significantly and impressively reduced liver fibrosis by up to 60% in a mouse model and is now in stage 2 clinical trials for treating NASH and chronic kidney fibrosis. I've repeatedly seen stated that those dosages aren't used in humans ,but that's actually not...- Mauritio
- Thread
- bromantane dopamine fibrosis kidney fibrosis ladasten liver fibrosis nafld nash np-160
- Replies: 18
- Forum: Scientific Studies
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Oral testosterone + vitamin E may treat NAFLD, NASH, cirrhosis in humans
Several years ago, I posted a few studies from the 1970s demonstrating very high cure rates of advanced cirrhosis in humans with a combination treatment of testosterone (T) and vitamin B1 (thiamine). Not bad for a condition modern medicine tells us is incurable and the only option the patient...- haidut
- Thread
- cirrhosis liver nafld nash testosterone tocopherol vitamin e
- Replies: 7
- Forum: Scientific Studies
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Glycine (and leucine) can treat fatty liver (NAFLD and NASH)
A great new study that demonstrates the strong protective effects of glycine, alone or in combination with leucine, on preventing/treating various forms of fatty liver disease, as well as the obesity that often accompanies these conditions. One of the strong points of the study is that it also...- haidut
- Thread
- diabetes glycine inflammation leucine liver nafld nash obesity pufa
- Replies: 3
- Forum: Scientific Studies
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Glycine Ameliorates NAFLD By Modulating FAO, Glutathione Synthesis, And The Gut Microbiome
Altered the title to make it fit. Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome Full text ABSTRACT Nonalcoholic fatty liver disease (NAFLD) including nonalcoholic steatohepatitis (NASH) has reached epidemic...- Ras
- Thread
- fatty acid oxidation glutathione glycine inflammation microbiome nafld nash
- Replies: 0
- Forum: Amino Acids
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Blocking Serotonin Treats Fatty Liver Disease (NAFLD / NASH)
The bad news for serotonin just keeps on coming. Just minutes ago I posted about serotonin turning people into violent criminals, and being the actual cause of depression instead of its cure (as FDA and Big Pharma would have you believe). Now, the study below adds another pathology that is...- haidut
- Thread
- 5-ht 5-ht2 cause fatty liver hepatic nafld nash serotonin
- Replies: 2
- Forum: Scientific Studies
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Vitamin E Can Treat/cure Severe Fatty Liver Disease (NASH) In Humans
As many of my readers know, currently there is an epidemic of the condition known as non-alcoholic fatty liver disease (NAFLD). By some estimates, more than 30% (100mil) of people living in the US have NAFLD and in about 25% of those the condition will progress to the more severe form known as...- haidut
- Thread
- cure disease liver nafld nash reverse tocopherol treat vitamin e
- Replies: 19
- Forum: Scientific Studies
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Epidemic Of NAFLD And NASH In Young People
Yet another sad reminder of just how much the health of the average person has declined over the last 20 years. They truly are becoming the "new old". The "Young" Have Now Become The Old If these trends are not reversed or at least slowed down, we may start seeing people in their 20s filing for...- haidut
- Thread
- cirrhosis disease fibrosis liver nafld nash steatosis young
- Replies: 11
- Forum: Scientific Studies
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Vitamin E Lowers Mortality, Transplantation Need In Liver Disease Patients
Good study on the protective effects of vitamin E on progression of the liver disease known as NASH, which usually leads to cirrhosis and eventually a need for liver transplant. It is nice to see Big Pharma opening up to treatment with vitamins, but it is probably due to the failure of their...- haidut
- Thread
- cirrhosis fatty liver liver disease lower mortality nash reduce tocopherol transplantation vitamin e
- Replies: 1
- Forum: Scientific Studies
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Liver Disease Is Caused By Low ATP Driven By Fat (PUFA) Oxidation
I posted a study several months ago on the ability of inosine to prevent/reverse liver disease, and how liver damage caused by various toxins was due to lower ATP levels in the liver. Inosine, being both a metabolite and precursor of ATP, is able to restore ATP levels and as such to...- haidut
- Thread
- atp cardiolipin cirrhosis fao fas fatty acid oxidation fatty acid synthesis liver liver disease mitochondrial dysfunction nafld nash peroxidation pufa
- Replies: 25
- Forum: Scientific Studies