Due to excessive bot signups along with nefarious actors we are limiting forum registration. Keep checking back for the register link to appear. Please do not send emails or have someone post to the forum asking for a signup link. Until the current climate changes we do not see a change of this policy. To join the forum you must have a compelling reason. Letting us know what skills/knowledge you will bring to the community along with the intent of your stay here will help in getting you approved.
This is just just another angle showing how stress hormones and PUFA affect the whole body negatively.
Increased Blood-brain-barrier permeability(leaky brain) is linked to many diseases :
"Blood–brain barrier dysfunction contributes to pathology in a range of neurological conditions including...
Just a few days ago I posted the groundbreaking study on metabolic derangement in ALS - i.e. it is a diseased characterized by increased FAO, which wastes glucose. Simply increasing dietary glucose was able to greatly restrain the pathology...
As many forum users may have noticed, there has been a dramatic increase in celebrities announcing they or a loved one have been diagnosed with multiple sclerosis (MS). The condition affects the central and peripheral nervous system and can lead to profound muscle weakness requiring the use of...
It seems that pregnenolone is finally starting to look exciting to the medical industry. In addition for its intensive studies for a variety of mental issues, now studies are coming out demonstrating its endotoxin (LPS) antagonism effects. As most forum users know, endotoxin exerts its effects...
A few years ago I posted a study showing that 1.2g aspirin daily greatly ameliorated fatigue in MS patients and was considered safe enough even at that high dose to be recommended for daily use.
Sunlight And Aspirin Can Treat Multiple Sclerosis (MS)
However, those studies did not look at...
A few users ( @aguilaroja ) posted recent case studies showing that biotin in doses as "low" as 10mg daily can interfere with lab test results and produce false positives for a number of conditions. Perhaps the most widely publicized interference is related to thyroid lab tests. Several people...
As most of the forum users know, MS is a chronic demyelination disease for which there is officially no cure. However, it is know that pregnant women experience complete remission and the condition exacerbates post-pregnancy, which emphasizes the protective role of progesterone and the...
The link between sunlight exposure and incidence of MS is well-known and strongly pointed to a metabolic origin of the disease as early as the 1960s. It led to a few underpowered trials with low dose vitamin D, which did not find much benefit. However, a recent trial with a higher dose (10,000...
It has been shown that progesterone rapidly metabolizes into more saturated metabolites such as 5α-Dihydroprogesterone (5α-DHP) and tetrahydroprogesterone (also known as allopregnanolone or Allo). The enzyme 5-AR is the one responsible for the saturation, just as it is responsible for the...
I must have gotten over 500 emails over the last year angrily reproaching me for talking negatively on the Danny Roddy shows about the "beneficial" gut flora in humans. I even got a few angry phone calls from actual MD professionals saying that the "science" behind beneficial effects of the...