mitochondria

  1. haidut

    Red Light Therapy For Parkinson Disease (PD) Begins Human Trials

    A few weeks ago, I posted about a human study demonstrating reversal of age-related vision decline by staring at a red light for just a few minutes a day. The mechanism of action proposed in that study had to do with improved mitochondrial function and energy production. Now, it seems another...
  2. RealNeat

    Cell Free Mitochondria?

    Researchers Find Cell-Free Mitochondria Floating in Human Blood what do we suppose is the reasoning behind this? Does it in some way expand upon, microvesicles, exosomes, cell to cell communication? Or is it just remnants of the "life cycle" of a blood cell.
  3. S

    Starting Anti Glycolytic Kettlebell Training

    Using Pavel's The Quick and the Dead. Not too sure what to put in log here, so here goes: Age 53 Sex M Weight 248 Height 5'11" Waking temp: 98.2 - 98.8 Health and stats steadily improving over last 8 months of Peating. This type of trainingg is supposed to increase ATP and mitochondrial...
  4. haidut

    Low Metabolism, Cellular Debris May Cause Huntington Disease (HD)

    Yet another study demonstrating the crucial role of oxidative metabolism (OXPHOS) in a chronic degenerative condition considered largely genetic in origin. Just as importantly, the study corroborates findings from other recent reports/experiments demonstrating that the presence of cellular...
  5. noqcks

    Neurometabolic Mechanisms For Memory Enhancement And Neuroprotection Of Methylene Blue

    Posting some interesting information from this paper. Read the full paper if you are interested in the hypothesized reason MB is helpful for memory. ---- Mechanism of Action "MB not only has great affinity for nervous tissue, it has also been recognized as one of the most potent...
  6. Tristan Loscha

    Monocyte Mitochondrial Function In Calcium Oxalate Stone Formers

    Monocyte Mitochondrial Function in Calcium Oxalate Stone Formers Urology. Author manuscript; available in PMC 2017 Jul 1. Published in final edited form as: Urology. 2016 Jul; 93: 224.e1–224.e6. Published online 2016 Mar 10. doi: 10.1016/j.urology.2016.03.004 PMCID: PMC4914421 NIHMSID...
  7. haidut

    Cardiolipin Supplementation May Reverse Signs Of Aging

    One of the key features of aging is the decline in mitochondrial function (metabolism), and that fact is widely recognized even by mainstream medicine. However, doctors still claim that the relationship between metabolic decline and aging has not be elucidated and a causative link cannot be...
  8. haidut

    Mad Cow Disease May Be A Mitochondrial/metabolic Issue

    Peat has mentioned the Creutzfeldt-Jacob disease (CJD) / BSE in several of his articles and interviews and has explained how environmental stress, estrogen, PUFA, ionizing radiation, etc can cause metabolic derangements resulting in the same brain damage so characteristic of this pathology. The...
  9. haidut

    Aspirin Protects Mitochondria From Inflammation And Aging

    The good news about aspirin just never seem to stop. While the anti-inflammatory effects of aspirin are well-known, mainstream medicine like to explain them away with the limited (and frankly primitive) mechanism of COX inhibition alone. If aspirin happens to achieve some other beneficial health...
  10. haidut

    Restoring Metabolism Prevents / Reverses "permanent" Nerve Damage

    Yet another study demonstrating the crucial role cellular metabolism plays in pathological processes. While most of my posts deal with beneficial effects of improving OXPHOS on various chronic diseases, the study below demonstrates that the same may be true in acute pathologies such as traumatic...
  11. haidut

    Restoring Energy Production In Immune Cells Is Therapeutic In Cancer

    The title of the popular press article is kind of the reverse of mine - i.e. cancer cells evade treatment by blocking energy production in immune cells (T-cells). However, my title still holds since the actual study did show that restoring energy production in T-cells restores the effectiveness...
  12. haidut

    Exposure To Fluoride Actually Damages Teeth, Even At Low Concentrations

    Most adults are familiar with the much-publicized (and advertised) claims of public health authorities about the purported benefits of fluoride exposure for dental health. The official story is that by adding fluoride to tap water, people's teeth are exposed to "low" concentration of fluoride...
  13. haidut

    Some ALS Cases May Be Cured By Vitamin B2 (riboflavin)

    A rather fascinating case study/report, which, despite its misleading and convoluted description, suggests yet again that motor neuron diseases such as Amyotropic Lateral Sclerosis (ALS) are nothing but severe mitochondrial/energetic dysfunction that can often be remediated quite easily. This is...
  14. haidut

    Low Dose Lithium May Stop Alzheimer’s Disease (AD) In Its Tracks

    This study was sent to me by one of my Twitter followers. In some of my past interviews/podcasts, I did mention isolated published case studies, as well as anecdotal medical reports of even advanced cases of AD getting rapidly reversed by micro-dosing regimens using lithium salts such as...
  15. haidut

    How Chronic Stress (cortisol) Causes Disease

    Back in 2018 I did a post on a neat study that demonstrated how the presence of cellular (mitochondrial) fragments in the blood stream acts identically to the pituitary hormone ACTH and as such activates the HPA axis. The more cellular fragments are in the bloodstream the more intense the stress...
  16. haidut

    Increasing Metabolism May Reverse Alzheimer Disease (AD) And General Aging

    Yet another study demonstrating the remarkable parallels between the decline in function (metabolism) and the structural abnormalities that occur not only in specific pathologies such as AD but also in the generalized degradation known as "aging". FDA currently does not recognize aging as a...
  17. haidut

    Progesterone May Treat Diabetes, Obesity, And Metabolic Syndrome

    Interesting new study, which adds more to the already existing mountain of evidence for the benefit of progesterone in a variety of conditions of metabolic origin. While the study does not mention any specific doses, it is known that the receptor (PGRMC2) whose activation the study found to be...
  18. haidut

    Aging Likely Caused By Decreased Respiration / Metabolism, Not Genetic Mutations

    It looks like after a century of utter idiotism in biology and medicine, those two disciplines may finally be getting on the right course. Despite the fact that the "rate of living" theory is still the dominant theory of aging in the halls of academia, a new generation of scientists is emerging...
  19. haidut

    Blue Light Accelerates Aging And Reduces Lifespan By More Than 50%

    In one of his interviews, Peat mentioned that red light exposure may be the most fundamental protective factor in nature, and that a deficiency of it (as commonly seen in Western lifestyles) may be the main driver of systemic aging and the diseases associated with it. The study below provides...
  20. haidut

    Energy Deficiency Due To Stress Causes Anxiety, Panic Disorders, And Subbordination

    This is a great study on so many levels. First, it directly demonstrates that chronic stress leads to mitochondrial dysfunction and reduced oxidative phosphorylation. Second, it demonstrates that glucocorticoids (cortisol) are a direct cause of this energy production downregulation. Third, it...
Back
Top Bottom