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mitochondria
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Infrared/red light applied to the skull can treat Alzheimer's/dementia...
...and improve cognition even in healthy people! The mechanism of action is the familiar effects of red/infrared light on stimulating mitochondrial function, and especially complex IV, while also decreasing chronic inflammation. The regimen was light exposure for 6min, twice a day, for 4 weeks...- haidut
- Thread
- alzheimer atp dementia infrared mitochondria oxphos red light
- Replies: 10
- Forum: Scientific Studies
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Science shows that humans are only 6,000 years old (mtDNA)
View: https://youtu.be/iWshBFUXYNs At the timestamp 8:04 (8 minutes and 4 seconds) the presentation is given that based on the evolutionary rate of the mitochondrial clock of women, the first woman lived about 6,000 years ago, which aligns with the written words of the King James Bible. The...- Twohandsondeck
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- mitochondria mitochondrial clock mutation salvation
- Replies: 20
- Forum: Meditation, Mindfullness, Religion, Spirituality
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How lipolysis may damage organs such as the heart
It is well-known in endocrinology, and especially among doctors specializing in diabetes, that excessive lipolysis is highly detrimental not only for the overall progression of metabolic diseases like diabetes, but also for most of the organs of the patient. Lipolysis is known to be elevated in...- haidut
- Thread
- adipocytes debris fibrosis heart lipolysis mitochondria ros
- Replies: 0
- Forum: Scientific Studies
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Cellular "memory" of stress can be passed on for 50+ generations
There was a study that came out 2-3 years ago showing that when animals were exposed to a toxin, often the negative effects did not even manifest in the directly exposed organism but manifested in their offspring and were passed on for more than 14 generations. The study below now demonstrates...- haidut
- Thread
- brain epigenetic generations inherited mitochondria neurons stress
- Replies: 8
- Forum: Scientific Studies
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Intense exercise causes mitochondrial damage even in elite athletes
Hopefully, this post won't be interpreted as trying to bash exercise. Its goal is to simply draw attention to the fact that intense exercise can be detrimental even for elite athletes. While the damage the study observed was temporary, it is now known that (just like ionizing radiation) the...- haidut
- Thread
- athlete damage endurance exercise fatigue mitochondria overtrain running
- Replies: 11
- Forum: Scientific Studies
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Damaged mitochondria may cause 90%+ of Parkinson Disease (PD) cases
More evidence that yet another "incurable" condition is little more than energy deficit (due to mitochondrial dysfunction) in disguise. In this case the mitochondrial dysfunction was caused by accumulation of mitochondrial debris inside the cell, which has been repeatedly shown by other studies...- haidut
- Thread
- damage dementia mitochondria oxphos parkinson stress
- Replies: 9
- Forum: Scientific Studies
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Aging is an energy deficiency problem, taking cardiolipin may reverse it
Yet another study demonstrating that "aging" is nothing but a phenotype characterizing an organism with declining energy production. Since most of the cellular energy is produced in the mitochondria, another way of stating the same is that aging (and any specific disease for that matter) is a...- haidut
- Thread
- aging cardiolipin disease energy lifespan mitochondria oxphos
- Replies: 8
- Forum: Scientific Studies
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COVID-19 is an energy deficiency disease
Yet another seemingly non-metabolic disease turns out to be nothing but energy deficiency in disguise. Apparently, the SARS-CoV-2 virus selectively disables so-called complex I of the electron transport chain (ETC), and as such the overall OXPHOS process. Such inhibition is known to reliably...- haidut
- Thread
- complex i covid-19 electron transport chain energy etc mitochondria oxphos sars-cov-2
- Replies: 5
- Forum: Scientific Studies
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Loss of mitochondrial function (OXPHOS) induces de-differentiation (cancer)
The study only focuses on the lymphatic system and its cells, but the principle is general and has been observed in other organ/tissue cells. The most obvious example is cancer - no matter which organ it occurs in, the tumor is composed of de-differentiated cells not unlike the stem cells from...- haidut
- Thread
- cancer differentiation electron transport chain etc loss mitochondria oxphos
- Replies: 0
- Forum: Scientific Studies
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Mitochondrial dysfunction may be the cause of anemia
Despite anemia being a pretty common condition, I still don't think medicine has a good idea what causes anemia (putting aside the more obvious reasons such as chronic bleeding and dietary iron deficiency). In one of the KMUD interviews Peat opined that in his opinion true iron deficiency...- haidut
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- anemia coq10 energy epo mitochondria rbc vitamin k
- Replies: 2
- Forum: Scientific Studies
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Muscle weakness / wasting linked to poor mitochondrial function
A study that once again illustrates the central principle of bioenergetics - structure and function cannot be separated. They are interdependent at every level. In this specific case, the "structural" pathology is muscle weakness and wasting (sarcopenia, cachexia, etc). Most doctors, when...- haidut
- Thread
- atp atrophy cachexia mitochondria muscle weakness oxphos sarcopenia
- Replies: 4
- Forum: Scientific Studies
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Vitamin D deficiency impairs muscles by lowering energy production
Perhaps this study below will put some of the arguments against vitamin D supplementation to rest. It demonstrated up to 40% reduction of energy production in the muscles of animals deficient in vitamin D, in spite of unchanged number/size/density of mitochondria inside the cells. In addition...- haidut
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- cholecalciferol energy mitochondria muscle oxphos sarcopenia vitamin d vitamin d3
- Replies: 2
- Forum: Scientific Studies
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Cool coffee video
View: https://youtu.be/rNbWDnUMaEk This video talks a lot about the key reasons Peat and others in the bioenergetic community think coffee is so valuable. Well done.- Outdoctrination
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- caffeine coffee cortisol endotoxin mitochondria stress hormones
- Replies: 2
- Forum: Coffee
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Metabolic (energy) deficiency may be the cause of Parkinson Disease (PD)
The dogma that PD is just a simple dopamine deficiency manifesting in genetically vulnerable individuals is quickly becoming untenable. It is well-known among clinicians that administering dopamine precursors such as L-Dopa, or selective dopamine agonists such as pramipexole has limited...- haidut
- Thread
- deficiency energy mitochondria parkinson pd ros
- Replies: 25
- Forum: Scientific Studies
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Mitochondrial debris leaking in bloodstream may cause autoimmune disease
This has been a recurring topic in my posts, and I am glad to see that more and more scientists are starting to take seriously the idea that chronic stress may be the ultimate cause of most/all "autoimmune" conditions. The whole idea of the immune system suddenly starting to attack an...- haidut
- Thread
- autoimmune debris dna mitochondria mitophagy rna tlr7
- Replies: 2
- Forum: Scientific Studies
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Inhibiting respiration/metabolism reliably causes bipolar disorder
Just a quick post on a study, which claims to have established a reliable method for inducing bipolar disorder in an animal model. This reliable method consists simply of administering a low-dose of a mitochondrial inhibitor. More specifically, an inhibitor of complex I of the electron transport...- haidut
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- bipolar disorder depression etc mania mitochondria oxphos
- Replies: 0
- Forum: Scientific Studies
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Glucose + vitamin B3 combo synergistic for treating mitochondrial disease
A very interesting study, which demonstrates the unique synergy between glucose and vitamin B3 in treating deficiencies of function in Complex I & II of the electron transport chain (ETC). Deficiencies on those metabolic steps are the most common causes for the wide varieties of debilitating...- haidut
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- disorder electron transport chain glucose mitochondria niacinamide synergy vitamin b3
- Replies: 11
- Forum: Scientific Studies
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Keto (low-carb) diet causes heart fibrosis, blocks mitochondrial biogenesis
The bad news for the low-carb / keto community keep piling on. There are a number of posts on this blog about studies demonstrating insulin resistance, diabetes, obesity and even sarcopenia as a result of low-carb diets or their close mimetic known as intermittent fasting. Now, the study below...- haidut
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- fao ffa fibrosis heart keto ketone low-carb mitochondria sirt7 sirtuin
- Replies: 17
- Forum: Scientific Studies
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Why Omega 3 should be avoided and what to use/do instead
Since there are so many discussions and confusion on this forum around omega 3s, I thought I do a deep dive and write this article. If there are so many studies showing that it's good and has so many benefits, how can it be bad...- Hans
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- cardiolipin dha epa fish oil immunosuppression lipid peroxidation mitochondria omega 3
- Replies: 20
- Forum: Articles & Scientific Studies
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Dying Organs Restored to Life through mitochondrial transplant
https://www.nytimes.com/2018/07/10/health/mitochondria-transplant-heart-attack.html