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metastasis
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Most cancers overproduce cortisol, and it accelerates their growth
This post is right on the heels of the one I just did on cortisol stimulating its own production and driving cardiovascular disease, obesity, diabetes, etc. The study below demonstrates that most tumor types known to medicine overexpress the rate-limiting enzyme for cortisol synthesis known as...- haidut
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- cancer cortisol feedback glucocorticoid immunity tumor
- Replies: 3
- Forum: Scientific Studies
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Fasting/exercise/lowcarb/keto may promote cancer (melanoma) metastasis
Quite the title for this post, but I think the evidence from the study below is clear. Namely, chronic activation of the so-called "master metabolic sensor" AMPK is a key mechanism through which melanoma cells rewire their metabolism from higher into lower OXPHOS, change their physical structure...- haidut
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- ampk cancer exercise fao fasting fission lowcarb melanoma mitochondria oxphos paleo
- Replies: 29
- Forum: Scientific Studies
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Evaluation Of The Role Of Melatonin In The Metastasis Of Papillary Thyroid Carcinoma
Article in Chinese; Abstract available in Chinese from the publisher] Fan L1, Xiong YP1, Liu HT1, Min X1, Tang YQ1, Zhang ZY1. Author information 1 Department of Otolaryngology Head and Neck Surgery，First Affiliated Hospital of Nanchang University，Nanchang，330006，China. Abstract in English...- S.Seneff
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- carcinoma melatonin study thyroid
- Replies: 1
- Forum: Scientific Studies
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Blocking Cystine, And Thus Glutathione (GSH) Synthesis, Kills Cancer Stem Cells
Yet another study that adds to the evidence that cancer is a metabolic disease, driven by excessive reductive stress. I posted a few other threads on the role of glutathione precursors in cancer, and specifically on the role of cysteine in melanoma. In the body, cysteine gets converted into...- haidut
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- cancer cysteine cystine glutathione growth nac spread stem cells uptake
- Replies: 82
- Forum: Scientific Studies
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SIRT1 Is A Key Promoter Of Leukemia And Other Blood Cancers
SIRT1 (one of the sirtuin genes) is currently one of the stars in the nutritional/medical blogosphere. As far as back as 2004, SIRT1 was promoted as a key regulator of longevity and activating this gene was marketed as one of the most reliable ways of increasing lifespan. Resveratrol was lauded...- haidut
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- accelerate cancer drive fao fatty acid oxidation hematologic leukemia malignancy promote sirt1 sirtuin sitruins
- Replies: 23
- Forum: Scientific Studies
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Cancer Transmitted By Organ Transplant, Curable If Immune System Is Intact
This is a fascinating study that shows organ donation from a person with undiagnosed breast cancer resulted in cancer developing in the organ recipients. This suggests that even in the case of localized tumors, the rest of the body is already in "cancer mode" and seemingly healthy...- haidut
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- cancer donor immune system immunosuppression organ recipient survival transmit transplant
- Replies: 0
- Forum: Scientific Studies
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Fatty Acid Oxidation (FAO) Makes Cancer Therapy-resistant, Niacinamide May Help
Yet another study that shows FAO playing a crucial role in cancer progression. As many forum users know, anti-angiogenic therapies are one of the cornerstones of current cancer treatments. This therapy typically uses the so-called VEGF inhibitors to block the formation of new blood vessels in...- haidut
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- angiogenesis cancer cpt1 fatty acid oxidation hypoxia inhibitor lipolysis mildronate niacinamide progression tumor vegf
- Replies: 0
- Forum: Scientific Studies
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It's Official - Cancer Surgery Drives Metastasis, Aspirin Can Prevent Them
The appearance of metastases has long been considered one of the most mysterious and important aspects of cancer due to the fact that metastases can occur even in organisms where the primary tumor has been completely removed and the rest of the organism has been completely isolated form the...- haidut
- Thread
- aspirin cancer drives immune system lethal nsaid progression surgery
- Replies: 9
- Forum: Scientific Studies
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Dietary Fat And Its Oxidation Drives Cancer Metastasis
Yet another study that discover cancer cells love for fat. As I posted in a few other threads, cancer cells actually need fat (preferably PUFA) for metastasis and survival, and use sugar for ATP generation. Achilles Heel Of Cancer Found - Its Addiction To Fat Cancer Cells Addicted To Fat And Use...- haidut
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- cancer cd36 cell fat inhibitor lipid preference
- Replies: 32
- Forum: Scientific Studies
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Niacinamide Fully Prevents Breast Cancer Metastasis
In yet another winning day (as Trump likes to say) for niacinamide, this study shows that the metastatic process of breast cancer is controlled by the NAD/NADH ratio, and NAD precursors like niacinamide can be effective chemotherapeutic agents. The human equivalent dose was 3g - 3.5g daily for a...- haidut
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- breast cancer nad nad+ nadh niacinamide prevention
- Replies: 3
- Forum: Scientific Studies