metabolism

  1. sladerunner69

    Intense Exercise Damages Cells In Ways That Cumulatively Impair Metabolism

    "Intense exercise damages cells in ways that cumulatively impair metabolism."-Dr. Raymond Peat Anyone believe this is true and what exactly does he believe is intense exercise? Marathon running? bicycling? What about weight training like heavy squats and deadlifts?
  2. haidut

    Vitamin B2 (FAD) (not Light) May Control The Circadian Clock

    Hopefully this won't spur another war on words as the previous discussion on the circadian clock. This study found that the coenzyme FAD (a derivative of riboflavin) control the circadian clock in a light-independent manner. To make the matters even more "metabolic" so to speak, the levels of...
    • haidut
    • Thread
    • circadian circadian rhythm clock cryptochrome fad glucose light metabolism riboflavin vitamin b2
    • Replies: 26
    • Forum: Scientific Studies
  3. haidut

    Epigenetic Changes Can Be Passed Down For At Least 14 Generations

    The phenomenon of inheritance is a solidly established fact in medicine. The fact that having relatives who had chronic disease increases one's own risk for developing those diseases is one of the main arguments of the pro-genetic crowd given as a reason to pursue genetic explanation of...
    • haidut
    • Thread
    • disease environmental epigenetic generation genes heritability inheritance metabolism pathology
    • Replies: 5
    • Forum: Scientific Studies
  4. haidut

    More Dietary Salt Increases Urea Synthesis And Energy Requirements

    The salt recommendations mentioned by Peat in some of his articles have been the source of much controversy. He has given accounts of people with various conditions recovering when they increased their salt intake to 1-2 tablespoons daily. I also posted studies showing that when sodium intake is...
    • haidut
    • Thread
    • atp homeostasis hunger metabolism osmolyte rmr salt sodium thirst urea
    • Replies: 68
    • Forum: Scientific Studies
  5. haidut

    Children Notice/learn Everything, Adults Have Selective/focused Attention

    I think the most important finding of the study is that adults are actually capable of noticing and remembering a lot more, but they have to be told to pay attention to everything, otherwise they stay focused on one thing. This focused-by-default is likely the result of years of damaging...
    • haidut
    • Thread
    • adults attention children flexible focused inflexible information learning metabolism remembering
    • Replies: 17
    • Forum: Scientific Studies
  6. haidut

    Exposure To EMF May Cause ALS

    I am posting this not so much because the link is strong but because the official message is that EMF is "completely benign" and cannot cause any disease because there is no known mechanism of action for it. That is of course a lie, and I posted a Q&A on Reddit that occurred a few years ago in...
    • haidut
    • Thread
    • als causative electric shock electrical fields electromagnetic radiation emf metabolism mitochondria neurodegenerative
    • Replies: 19
    • Forum: Scientific Studies
  7. haidut

    Lifespan / Longevity May Be Tied To Environmental Conditions

    While I do not agree with the main assertions of the author on "rate of living" theory, he does make a few very important points, including the vital importance of mitochondria and metabolism for evolution and lifespan. Also, he lists a few examples of species where lifespan doubled simply...
    • haidut
    • Thread
    • adversity evolution lifespan longevity metabolic rate metabolism mitochondria ros
    • Replies: 0
    • Forum: Scientific Studies
  8. haidut

    Metabolism May Be Older Than Life Itself And Can Start Spontaneously

    If this is indeed true I am not sure how can modern medicine continue to deny the primary role of metabolism in the human organism. The picture so far suggests that metabolism appeared first, then RNA and finally DNA. The same group published two studies. The first one showed that glycolysis can...
    • haidut
    • Thread
    • catalyst cell glycolysis krebs cycle life metabolism precedes primordial quinones radicals spontaneous
    • Replies: 8
    • Forum: Scientific Studies
  9. haidut

    CFS/ME Once Again Confirmed As A Metabolic Disorder

    I posted previously about recent research indicating that CFS/ME is likely due to hypometabolism caused by environmental stress. CFS Is Likely Hypometabolism Triggered By Environmental Stress The earlier studies found lower activity of the enzyme PDH, which is the rate-limiting step for entrance...
    • haidut
    • Thread
    • atp cfs chronic fatigue syndrome citric acid cycle environmental krebs cycle low me metabolic metabolism pdh
    • Replies: 13
    • Forum: Scientific Studies
  10. haidut

    Optimal Dose Of Niacinamide For Stimulating Respiration

    As many of you know, the Wikipedia page has a warning not to take more than 3g daily as it may elevate liver enzymes. I traced the warning to a few studies with high dose niacinamide using 4g - 6g daily for conditions like HIV and arthritis. However, they did not provide an explanation on why...
    • haidut
    • Thread
    • concentration dose liver metabolism nad niacinamide optimal respiration
    • Replies: 26
    • Forum: Scientific Studies
  11. haidut

    Chronic Fasting / Famine Can Cause Diabetes And The Adaptation Is Hereditary

    Yet another study that shows why chronic fasting is not likely to lead to good long term outcomes for your health. While it can be argued that famine is not the same as fasting, the level of caloric restriction required to see the benefits reported in animal studies comes pretty close to what...
    • haidut
    • Thread
    • diabetes epigenetic famine fasting hereditary hyperglycemia metabolism offspring
    • Replies: 7
    • Forum: Scientific Studies
  12. haidut

    Children Conceived In Winter Have Much Higher Risk Of Autism

    Not sure why the study considers January to May to be winter months, but this is yet another study that links maternal metabolism (and serotonin) to autism. The official explanation is increased flu infection and lower vitamin D levels in the winter. While these may be contributing factors, I...
    • haidut
    • Thread
    • autism conceiving conception disabilities dyslexia flu hypothyroidism maternal metabolism serotonin vitamin d winter
    • Replies: 4
    • Forum: Scientific Studies
  13. J

    "Higher Metabolism, Temperature And Pulse And Lower TSH Associated With Higher Mortality"

    WTF is this??? Higher metabolism, temperature and pulse and lower TSH associated with higher mortality
    • Jarman
    • Thread
    • metabolism mortality peatarian reviews (bukowski) pulse temperature tsh
    • Replies: 156
    • Forum: Ray Peat Topics
  14. haidut

    Androsterone Is A Potent Agonist / Activator Of The Farnesoid X Receptor (FXR)

    The so-called Farnesoid X Receptor (FXR) is a very interesting nuclear receptor inside the cell. It has a multitude of functions, but one of the main functions includes sensing and controlling the levels and synthesis of bile acids. As I mentioned in a few other posts, nuclear receptors...
    • haidut
    • Thread
    • activator agonist androsterone bile acid farnesoid fxr liver metabolism mitochondria study
    • Replies: 42
    • Forum: Scientific Studies
  15. haidut

    Androsterone - Liquid Androsterone For Lab/R&D

    Edit (10/6/2022): Androsterone seems to be indeed a very effective precursor to DHT in-vivo, as demonstrated by the test results discussed in the thread below. https://raypeatforum.com/community/threads/idea-labs-hair-test-for-androgens.47974/post-856197 EDIT: Since I keep getting questions...
    • haidut
    • Thread
    • anabolic androgenic androsterone anti-adrenaline antidepressant antidiabetic antiestrogen metabolism mimetic neurosteroid surrogate thyroid
    • Replies: 1,961
    • Forum: IdeaLabs
  16. haidut

    Androsterone - The Forgotten But Potent Thyroid Mimetic

    Androsterone is one of the 5-AR derived androgens and is a downstream metabolite of DHT. While modern medicine has almost completely forgotten about it, androsterone was well-known and widely used in the 1950s and 1960s under the commercial name Atromid - the most potent cholesterol and...
    • haidut
    • Thread
    • androsterone cholesterol hypothyroidism metabolism myxedema pyrogenic thyroid thyromimetic triglycerides
    • Replies: 18
    • Forum: Scientific Studies
  17. haidut

    Slower Metabolism In Puberty, Not Lifestyle, Causes Teen Obesity

    Ray has written about how children have fast metabolism and are much harder to make obese than adults. He also wrote that delaying puberty has beneficial effects on health and metabolism, largely due to the delay of getting adrenals involved in metabolism. In adults, adrenals are usually in...
    • haidut
    • Thread
    • adrenals metabolism obesity puberty ree rmr slowdown teen
    • Replies: 0
    • Forum: Scientific Studies
  18. haidut

    Red Light Treats PTSD By Upregulating Cytochrome C And Brain Oxygenation

    The US military has been pouring a lot of money into PTSD research, and especially non-chemical treatments. The official estimates, which are likely downsized due to political concerns, are that about 25% - 30% of combat veterans suffer from some stage of PTSD. The prescribed SSRI drugs are...
    • haidut
    • Thread
    • brain cytochrome c energetics hemoglobin lllt metabolism oxygenation ptsd red light study
    • Replies: 16
    • Forum: Scientific Studies
  19. haidut

    Human Pregnancy Length Controlled By Metabolism Speed, Not Pelvic Shape

    Ray has written in several of his articles that human pregnancy is controlled primarily by the amounts of progesterone produced by the mother while pregnant. When the baby reaches a size that the metabolism of the mother and hence the production of progesterone cannot maintain any longer, labor...
    • haidut
    • Thread
    • duration energetic gestation human metabolism pregnancy progesterone
    • Replies: 27
    • Forum: Scientific Studies
  20. haidut

    Fluoride In Tap Water Could Be A Causative Factor In Diabetes

    While the public health authorities continue their mantra on the "benefits" of fluoride for teeth and bone health, there are quite a few research groups that have been producing solid evidence to the contrary. As many of you know, fluoride is a proven thyroid inhibitor. As such, it is expected...
    • haidut
    • Thread
    • antagonist diabetes fluoride inhibitor metabolism tap water thyroid
    • Replies: 32
    • Forum: Scientific Studies
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