metabolism

  1. haidut

    Niacinamide May Be A Viable Treatment For Parkinson Disease (PD)

    It looks like the pharma industry is experiencing a resurgence in the search for metabolic therapies with patented chemicals. There must have been at least 50 different studies in 2017 alone with the NAD precursor nicotinamide riboside (NR) for conditions ranging from cancer, to glaucoma, to...
  2. haidut

    Children Have More Energy And Recover Faster Than Elite Endurance Athletes

    While endurance exercise is hardly the healthiest form of physical activity, triathlon runners are known for their ability to quickly clear lactate out of the blood and metabolite it back into glucose. The ability to handle lactate is good metric of metabolic health and the pyruvate/lactate...
  3. haidut

    Serotonin Causes Obesity And Diabetes In Humans

    This study is presented as groundbreaking and unexpected but in fact big pharma has been quietly working on anti-serotonin therapy for obesity/diabetes for more than a decade. I think the importance of this study is the admission that serotonin causes obesity/diabetes in humans, as one of the...
  4. haidut

    Topical Stearic Acid Is Metabolized Into Longer Chain SFA

    This seems like a very interesting study, but is in French and not available from PubMed. So, I am hoping @burtlancast would be able to obtain it and maybe translate the relevant fractions. The study shows that dietary stearic acid is both incorporated into cell lipids and metabolized further...
  5. haidut

    Chemicals Used In Packaging, Carpets And Utensils (Telfon) Are Endocrine Disruptors

    Whenever a news articles contains the phrase "endocrine disruptor" most people automatically think of chemicals like BPA, BPS and other related plasticisers. BPA and its related chemicals are known thyroid antagonists, estrogen agonists and androgen antagonists. The material commonly known as...
  6. haidut

    Environment (diet), Not Genetics, Mainly Shapes Gut Bacteria Composition

    As many forum users know, studying the microbiome is the current hot topic in biochemistry and imbalances in the microbiome are used to explain everything from depression, to CVD, to cancer. A major argument advanced in the microbiome analysis field is that genes are the main driver of the...
  7. haidut

    Biotin Can Actually Raise T4 And Lower TSH

    A few users ( @aguilaroja ) posted recent case studies showing that biotin in doses as "low" as 10mg daily can interfere with lab test results and produce false positives for a number of conditions. Perhaps the most widely publicized interference is related to thyroid lab tests. Several people...
  8. haidut

    Cardenosine - Liquid Product For R&D

    Our new product is finally here and it is "all about the ATP". I mentioned quite a few times on the forum and over email that we plan on releasing an ATP product and people have been asking me about it for the last few months. It seems a very simple task at first but we thought that we can do a...
  9. haidut

    Stearic Acid Increases Mitochondrial Function, May Treat Parkinson Disease (PD)

    I posted recently about the ability of dietary stearic acid to reduce abdominal fat accumulation by more than 70%. This study provides some insight as to what the mechanism of action behind that anti-obesity effect may be. The study below found that when stearic acid was fed at a dose of 10% of...
  10. haidut

    Methylene Blue Is A Potent Anti-inflammatory, With Possibly The Broadest Spectrum

    Some bold statements in this study, which combined both in vitro and in vivo models. The HED for methylene blue (MB) was just 0.15mg/kg, which is in the range of 10mg-15mg doses that showed great effectiveness in treating mental disorders like depression and psychosis. As you can see from the...
  11. haidut

    Naked Mole Rats Do Not Age

    Many forum users are familiar with the naked mole rat. Peat has mentioned them a few times and we have a few other posts about them on the forum. They are highly resistant to cancer, and while the mainstream medical view is that this is due to their special genes the much more likely explanation...
  12. haidut

    "Normal" TSH Above 2 As A Cause Of Unexplained Infertility

    As most of the people on this forum know, Peat has spoken many times about the optimal values of TSH and has said that its value should be as close to 0 as possible. I posted a study some time ago showing that "normal" TSH levels above 2 are associated with a number of health issues that baffle...
  13. haidut

    Allopregnanolone Levels Are Low In Both Obese And Anorectic Females

    This new study is one of the few that puts the spotlight on the role of hormones (and thus metabolism) in weight disorders. Most doctors and dieticians believe that being obese or anorectic is simply an issue of eating too much or too little. However, multiple human studies have shown that it is...
  14. haidut

    Bonobos Are Altruistic (without Payback And Without Encouragement)

    I have posted before studies in regards to the link between metabolism, energy and highly valued human qualities like altruism, and helpfulness. As has been confirmed in humans, egalitarian beliefs, altruism and generally friendly behavior towards complete (genetic) strangers requires good...
  15. haidut

    Human Study Confirms Alzheimer As A Metabolic Condition (brain Diabetes)

    Over the last 3 years I posted quite a few studies on Alzheimer disease (AD) and have discussed it at length in the Danny Roddy podcasts. Among the most successful interventions are niacinamide and methylene blue (MB) both of which are in human clinical trials, thyroid and aspirin. Alzheimer...
  16. haidut

    Lanosterol - Liquid Lanosterol For Lab/R&D

    I guess most people on the forum who have heard of lanosterol know it in the context of treating cataracts. Lanosterol - Wikipedia There is a company out there who used to sell lanosterol as eye drops and it is insanely expensive - $100 for a meager 10mg lanosterol. Anyways, lanosterol is...
  17. haidut

    In The Beginning There Was Metabolism, And Metabolism Said Let There Be Life

    I posted a thread long time ago about how the emergence of life was unavoidable given the basic physical laws of our Universe. https://raypeatforum.com/community/threads/the-emergence-of-life-was-virtualy-guaranteed.3071/ The same author (England) has since conducted a number of simulations and...
  18. haidut

    Even Wikipedia Says That Water Inside The Organism Has Structure

    Peat and Ling have written at length about the effects of various substances on water structure both inside and outside the cell and how that affects tissue oxygenation and metabolism. However, the idea is considered heretical in scientific circles. I have a few friends who are doctors or work...
  19. haidut

    More Intelligent People Live Longer

    Ray has written many times about the links between metabolism and intelligence, and metabolism and longevity. The mainstream view if that both traits (intelligence and longevity) are genetic and unrelated. Previous studies that found correlation between intelligence and lifespan ascribed it to...
  20. haidut

    Delirium (and Dementia/AD) Is Caused By Inability To Oxidize Glucose

    Ray has written about the metabolic origins of Alzheimer disease (AD) and I posted quite a few studies on the links between AD and PUFA metabolites as well as insulin resistance in the brain. I even mentioned on one of Danny Roddy's shows that there is a proposal by NIH to reclassify AD as...
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