metabolic rate

Just a quick post in regards to a study that found the drug donepezil - commonly used to "treat" Alzheimer's Disease (AD) - may improve mitochondrial function in muscles. While the findings of the study in regards to donepezil are debatable and not particularly interesting, buried inside the...

A great study, which once again puts metabolism in the spotlight. Many studies have tried to discover the main biological differences between children and adults and so far none of them have discovered a "smoking gun". At the same time, multiple studies have demonstrated that children are much...

A study that will certainly generate controversy in the low-carb blogosphere, but the findings are hard to dispute. Namely, feeding a diet for 15 weeks, in which 74.3% of the calories come from carbs in the form of starch was clearly obesogenic, caused insulin resistance and elevated blood...

Peat's central premise is that a high metabolic rate will improve chances of longevity. This is in direct contrast to the mainstream premise. (Just look up "metabolic rate longevity") to get an idea of this. I'm trying to gather up evidence for the idea that a higher metabolic rate gives us a...

This article is not all about bashing fat burners, but elaborates on the concept of metabolic rate, fat and glucose oxidation and common misconceptions when it comes to fat burners. https://men-elite.com/2021/03/05/the-only-thing-fat-burners-burn-is-your-wallet/ Let me know your thoughts.

Excess sugar consumption doesn't necessarily make you fat, if you have sufficient nutrients to use the carbs. "but the daily caloric intake was higher in the HS group in relation to the C and HFHS groups (HS: 92 ± 2.0 vs. C: 79.2 ± 2.6 and HFHS: 77.3 ± 1.7 kcal/day, p < 0.05)." And yet...

We examined the impacts of aspirin and metformin on the life history of the cricket Acheta domesticus (growth rate, maturation time, mature body size, survivorship, and maximal longevity). Both drugs significantly increased survivorship and maximal life span. Maximal longevity was 136 days for...

As most of my readers know, the currently approved therapy for hypothyroidism is levothyroxine (T4). While technically T3 and combined T4/T3 therapy are also approved by FDA, the former is only used in severe cases of myxedema and the latter is considered obsolete and a remnant of the days when...

Very cool study done in the 50’s. https://www.jstage.jst.go.jp/article/jjphysiol1950/2/0/2_0_303/_pdf

A few very interesting studies came out in 2018 showing that niacinamide may be very helpful for (pre)-eclampsia, as well as prevent miscarriages and birth defects. Keep in mind that according to mainstream medicine, eclampsia is untreatable and the approach is to have the baby delivered ASAP...

Whenever a news articles contains the phrase "endocrine disruptor" most people automatically think of chemicals like BPA, BPS and other related plasticisers. BPA and its related chemicals are known thyroid antagonists, estrogen agonists and androgen antagonists. The material commonly known as...

Low carbohydrate diet induces metabolic depression: a possible mechanism to conserve glycogen. - PubMed - NCBI Long-term studies have found low carbohydrate diets are more effective for weight loss than calorie restricted diets in the short-term, but equally or only marginally more effective...

Very much opposite to what ray says! Phosphate supplementation prevents a decrease of triiodothyronine and increases resting metabolic rate during low energy diet. - PubMed - NCBI Abstract Thirty overweight women participated in 8 week slimming program consisting of a self-controlled...

While I do not agree with the main assertions of the author on "rate of living" theory, he does make a few very important points, including the vital importance of mitochondria and metabolism for evolution and lifespan. Also, he lists a few examples of species where lifespan doubled simply...

"Eighty-one females were divided into three groups: adults (<65 yr old; n = 26), aged subjects (age range 66–94; n = 27), and long-lived subjects (>95 yr old; n = 28) volunteered for the study." "Indirect calorimetry parameters for each age group are reported in Table 3. Long-lived subjects had...

Maybe the metabolic rate is not so important after all. Mathematician/biologist Lloyd Demetrius suggested that the most important factor involved in duration of life is not metabolic rate or oxidative stress, but metabolic stability. "Evolutionary biologist Lloyd Demetrius believes that...

The type of behavior scientists consider risky is usually the exact behavior children and young adults seem so suited for - i.e. willingness to explore and learn even in the face of danger. This is yet another study to show that openness to new experiences, desire to explore novel environments...

How much of an increase in basal metabolic rate can we reasonably expect from eating the Peat way? If my bmr is 1000-1200 calories a day, how is eating this diet going to change that?