1. Y

    New Study: Vitamin D causes melanoma

    Circulating vitamin D concentration and risk of 14 cancers: a bidirectional Mendelian randomization study ...The MR analysis showed no causal relationship between circulating vitamin D concentrations and most types of cancer, except for a causal relationship with melanoma skin cancer (MSC) (odds...
  2. J

    Aspirin inhibits Melanin production.

    I came across the following diagram. Should we be concerned with our higher uses of aspirin. Perhaps the benefits outweigh the negatives. My apologies for the poor formatting and if this has been discussed already. Should this be of concern considering : - melanin absorbs heavy metals ( New...
  3. haidut

    Fasting/exercise/lowcarb/keto may promote cancer (melanoma) metastasis

    Quite the title for this post, but I think the evidence from the study below is clear. Namely, chronic activation of the so-called "master metabolic sensor" AMPK is a key mechanism through which melanoma cells rewire their metabolism from higher into lower OXPHOS, change their physical structure...
  4. haidut

    Doxycycline can CURE melanoma in humans

    A great study and perhaps the first that confirmed in humans the already well-known anti-cancer effects of the tetracycline antibiotic family. Considering the almost complete ban on the word "cure" scientific journals have bestowed on cancer-related publications using non-mainstream therapies...
  5. Mauritio

    Vitamin E succinate decreases melanoma size by 650% in vivo

    I have already posted a study about vitamin E succinate (VES) beeing able to decrease liver carcinoma by 77% (Vitamin E Succinate Very Effective Against Liver Carcinoma ,acetate Form Increases It) There have previously been studies on VES and melanoma in vitro and they all showed decreases in...
  6. haidut

    Melanoma Defined By Increased Fatty Acid Synthesis And Unsaturation

    Yet another study implicating dysregulated fatty acid, instead of glucose, metabolism in cancer cells. Namely, the expression and activity of the enzyme fatty acid synthase (FASN) is increased in melanoma cells. Another interesting finding of the study is the increased unsaturation of the...
  7. haidut

    Anti-histamines May Prevent, Treat Melanoma

    About 2 years ago I did a post discussing the hypothesis that melanoma is an endocrine tumor, similar to breast cancer - i.e. driven by estrogen. In fact, if one has the time to dig into the published literature on all known malignancies, it quickly becomes apparent that virtually all cancers...
  8. haidut

    Vitamin D May Stop Melanoma Growth

    A great study that corroborates my recent post on avoiding sunlight being as bad for health as smoking a pack of cigarettes a day. After all, without sunlight there won't be much vitamin D synthesis and supplementation is not effective for many people due to variety of factors including excess...
  9. haidut

    PUFA/Statins Promote UV Damage & Skin Cancer (melanoma), Cholesterol Is Protective

    Several people asked Peat over email about the dangers of sun exposure. He responded by saying that the main danger is the lipid (PUFA) perodixation caused by the UV lights and that taking some aspirin, vitamin E, or niacinamide greatly reduces the damage. The study below confirms that PUFA may...
  10. haidut

    Aspirin May Help Treat Melanoma

    A few months ago, a study made the rounds on social media and even this forum, claiming that aspirin actually increased risk of melanoma. Peat published a separate newsletter just to address that study. And now, this study below shows that aspirin actually may help treat Stage 2 and 3 melanomas...
  11. haidut

    Melanoma Is An Endocrine Tumor Like Breast Cancer - Driven By Estrogen

    Peat has said this a number of times in his articles, but to this day the mainstream view is that melanoma and all other skin cancers are driven by overexposure to sunlight. The fact that melanoma rates have skyrocketed over the last 20 years (perfectly coinciding with increased sunscreen use)...
  12. haidut

    Niacinamide May Prevent Melanoma

    About 2 years ago an Australian study hit frontpage news. It found that ingesting 1g niacinamide daily significantly reduced the risk of non-melanoma skin cancers. Vitamin B3 Prevents And Reverses Skin Cancer Now, a new study and a review found that the same dose of niacinamide may work for...
  13. haidut

    Estrogen Darkens Skin Color, Progesterone Lightens It

    It has been known since ancient Greek times that during pregnancy skin color in women changes drastically. Doctors have long suspected that hormones are involved but until now the mechanism was not known. This study shows that estrogen and progesterone are involved in skin color changes...
  14. haidut

    Pregnenolone For Protection Against Melanoma

    Ray has written a few times on the topic of "moles" and how he treated his with DHEA, T3 and progesterone. While he did not mention pregnenolone, I always wondered if it would have a similar effect as animal studies with pregnenolone noted lack of melanoma in treated animals subjected to UV...
  15. haidut

    NAC (cysteine) Increases Melanoma Spread

    Another point for Peat and his articles on how antioxidants can be pro-tumorigenic. The free radicals generated through high metabolism is what keeps some cancers in check. NAC (cysteine) blocks the effects of those free radicals. In addition, NAC also suppresses the thyroid so that may be...
  16. S

    Citrus Consumption and Risk of Cutaneous Malignant Melanoma

    Citrus Consumption and Risk of Cutaneous Malignant Melanoma
  17. haidut

    Melanoma Needs Glutamine To Grow And Dies Without It

    In support of Ray's opinion on amino acids like glutamine and arginine fueling cancer growth, this study found that melanoma cancer needs glutamine for its growth and without a steady supply of glutamine the cancer dies. So, glutamine and arginine restriction / depletion seem to be viable...
  18. haidut

    Coffee (caffeine) protects against melanoma

    The study supports once again Peat's statements, and even though it looked at coffee usage, it is likely that caffeine is the protective substance since decaffeinated coffee did not have much effect. The mechanism of action may be caffeine's effects of increasing levels of cAMP, which leads to...
  19. charlie

    Aspirin Vs. Melanoma: Study Suggests Headache Pill

    Aspirin Vs. Melanoma: Study Suggests Headache Pill Prevents Deadly Skin Cancer Source Rest of story at link above.